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中华肺部疾病杂志(电子版) ›› 2020, Vol. 13 ›› Issue (02) : 261 -264. doi: 10.3877/cma.j.issn.1674-6902.2020.02.029

短篇论著

长链非编码RNA SNHG16表达水平与肿瘤患者预后关系的Meta分析
刘娅1, 李才弘1, 刘长路1, 刘代顺1,()   
  1. 1. 563000 贵州,遵义医科大学
  • 收稿日期:2020-01-13 出版日期:2020-04-25
  • 通信作者: 刘代顺
  • 基金资助:
    遵义市科技局基金项目(2018.164)

Meta analysis of the relationship between expression level of long-chain non-coding RNA SNHG16 and prognosis of cancer patients

Ya Liu1, Caihong Li1, Changlu Liu1   

  • Received:2020-01-13 Published:2020-04-25
引用本文:

刘娅, 李才弘, 刘长路, 刘代顺. 长链非编码RNA SNHG16表达水平与肿瘤患者预后关系的Meta分析[J/OL]. 中华肺部疾病杂志(电子版), 2020, 13(02): 261-264.

Ya Liu, Caihong Li, Changlu Liu. Meta analysis of the relationship between expression level of long-chain non-coding RNA SNHG16 and prognosis of cancer patients[J/OL]. Chinese Journal of Lung Diseases(Electronic Edition), 2020, 13(02): 261-264.

表1 纳入研究的基本特征及评分
第一作者及发表年限 国家 肿瘤类型 研究涉及类型 例数 肿瘤分期或分级 LncRNA SNHG16高表达人数及表达率(%) 最长随访时间(月) 多因素分析 结局指标 HR(95%CI) 检测方法 NOS评分(分)
Han2017[11] 中国 NSCLC R 66 TNM Ⅰ-Ⅱ/Ⅲ-Ⅳ 33(50.0) 60 Yes OS/DFS Report qRT-PCR 8
Lin2019[12] 中国 HCC R 88 TNM Ⅰ-Ⅱ/Ⅲ-Ⅳ 37(42.0) 60 Yes OS SC qRT-PCR 8
Zhu2018[13] 中国 cervical cancer R 78 Grade Ⅰ-Ⅲ 22(28.2) 60 Yes OS SC qRT-PCR 8
Han2019[14] 中国 NSCLC R 66 TNM Ⅰ-Ⅱ/Ⅲ-Ⅳ 33(50.0) 80 Yes OS/DFS Report qRT-PCR 8
Li2019[15] 中国 CRC R 56 NA 28(50.0) 48 No OS SC qRT-PCR 7
Liao2019[16] 中国 osteosarcoma R 96 TNM Ⅰ-Ⅱ/Ⅲ-Ⅳ 48(50.0) 60 Yes OS SC qRT-PCR 8
Liu2019[17] 中国 PC R 46 TNM Ⅰ-Ⅱ/Ⅲ-Ⅳ 25(54.3) 60 No OS SC qRT-PCR 7
Lu2018[18] 中国 glioma R 48 Grade Ⅰ-Ⅳ 25(52.1) 60 Yes OS/PFS Report qRT-PCR 7
Peng2019[27] 中国 bladder cancer R 275 Grade G1-G3 187(86.0) 50 Yes CSS SC qRT-PCR 8
Wang2019[19] 中国 osteosarcoma R 56 TNM Ⅰ-Ⅱ/Ⅲ-Ⅳ 33((50.8) 60 No OS SC qRT-PCR 8
Zhong2019[20] 中国 HCC R 108 BCLC ABC 57(52.8) 60 No OS/DFS SC qRT-PCR 8
Cao2017[21] 中国 bladder cancer R 46 TNM Ⅳ 25(54.3) 60 No OS SC qRT-PCR 7
Guo2019[22] 中国 HCC R 61 Grade Ⅰ-Ⅳ 35(57.4) 60 Yes OS/DFS Report qRT-PCR 8
Han2018[23] 中国 ESCC R 128 TNM Ⅰ-Ⅱ/Ⅲ-Ⅳ 65(50.1) 60 Yes OS Report qRT-PCR 8
Yang2018[24] 中国 ovarian cancer R 103 TNM Ⅰ-Ⅱ/Ⅲ-Ⅳ 47(45.6) 60 No OS SC qRT-PCR 7
马秦榕等2019[25] 中国 LAD R 39 TNM Ⅰ-Ⅱ/Ⅲ-Ⅳ 14(35.9) 60 No OS SC qRT-PCR 6
周云松等2019[26] 中国 CRC R 60 Duke′S分期A-B/C-D 32(53.3) 50 No OS SC qRT-PCR 6
图1 LncRNA SNHG16高表达与预后指标OS关系图
图2 LncRNA SNHG16高表达与DFS/PFS的关系图
图3 漏斗图散点图
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