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中华肺部疾病杂志(电子版) ›› 2025, Vol. 18 ›› Issue (01) : 171 -175. doi: 10.3877/cma.j.issn.1674-6902.2025.01.032

综述

不同抗生素治疗MRSA 感染性肺炎的研究进展
刘玉强1,2, 侯春霞1, 成亚东3, 段金菊4, 孙凤5, 菅凌燕2,   
  1. 1. 046000 长治,长治市人民医院药学部
    2. 110004 沈阳,中国医科大学附属盛京医院药学部
    3. 046000 长治,长治市人民医院重症医学科
    4. 030001 太原,山西医科大学第二医院药学部
    5. 100191 北京,北京大学医学部公共卫生学院
  • 收稿日期:2024-10-13 出版日期:2025-02-25
  • 通信作者: 菅凌燕
  • 基金资助:
    山西省卫生健康委员会科研课题(2023109)

Research progress of different antibiotics in treatment of MRSA infectious pneumonia

Yuqiang Liu, Chunxia Hou, Yadong Cheng, Jinju Duan, Feng Sun, Lingyan jian   

  • Received:2024-10-13 Published:2025-02-25
  • Corresponding author: Lingyan jian
引用本文:

刘玉强, 侯春霞, 成亚东, 段金菊, 孙凤, 菅凌燕. 不同抗生素治疗MRSA 感染性肺炎的研究进展[J/OL]. 中华肺部疾病杂志(电子版), 2025, 18(01): 171-175.

Yuqiang Liu, Chunxia Hou, Yadong Cheng, Jinju Duan, Feng Sun, Lingyan jian. Research progress of different antibiotics in treatment of MRSA infectious pneumonia[J/OL]. Chinese Journal of Lung Diseases(Electronic Edition), 2025, 18(01): 171-175.

耐甲氧西林金黄色葡萄球菌(Methicillin-resistant Staphylococcus aureus,MRSA)具有较强的生存能力及传播性,是引发肺炎的常见菌种之一,具有广谱耐药性,给临床治疗带来巨大挑战。 近年来临床针对MRSA 感染性肺炎抗感染治疗药物的研究越来越多,其中万古霉素、替考拉宁、利奈唑胺、替加环素、克林霉素、达托霉素、头孢吡咯为常用抗生素,展现出良好的应用效果。 不同抗生素的作用机制、治疗效果、应用成本等存在较大差别,目前尚缺乏规范的使用标准,不同抗生素可能引发一系列不良反应,影响治疗效果,增加医疗资源浪费,未来需进一步规范与优化不同抗生素的使用方法,减少抗生素滥用及耐药情况的发生,需增加药物不良反应监测与预防,提高用药安全性。

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