1 |
Hirsch FR, Scagliotti GV, Mulshine JL, et al. Lung cancer: current therapies and new targeted treatments[J]. Lancet, 2017, 389(10066): 299-311.
|
2 |
She J, Yang P, Hong Q, et al. Lung cancer in China: challenges and interventions[J]. Chest, 2013, 143(4): 1117-1126.
|
3 |
Blandin KS, Crosbie PA, Balata H, et al. Progress and prospects of early detection in lung cancer[J]. Open Biol, 2017, 7(9): pii: 170070.
|
4 |
Aberle DR, Adams AM, Berg CD, et al. Reduced lung-cancer mortality with low-dose computed tomographic screening [J]. N Engl J Med, 2011, 365(5): 395-409.
|
5 |
Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps[J]. Nat Rev Genet, 2007, 8(4): 286-298.
|
6 |
Belinsky SA. Gene-promoter hypermethylation as a biomarker in lung cancer[J]. Nat Rev Cancer, 2004, 4(9): 707-717.
|
7 |
Tomasetti M, Amati M, Neuzil J, et al. Circulating epigenetic biomarkers in lung malignancies: From early diagnosis to therapy[J]. Lung Cancer, 2017, 107: 65-72.
|
8 |
Zhang C, Yu W, Wang L, et al. DNA Methylation analysis of the SHOX2 and RASSF1A panel in bronchoalveolar lavage fluid for lung cancer diagnosis[J]. J Cancer, 2017, 8(17): 3585-3591.
|
9 |
崔 超,张 军,李 淼,等. 支气管灌洗液P16基因启动子甲基化在非小细胞肺癌诊断中的应用[J]. 山东医药,2015(07): 36-38.
|
10 |
Tuo L, Sha S, Huayu Z, et al. P16(INK4a) gene promoter methylation as a biomarker for the diagnosis of non-small cell lung cancer: An updated meta-analysis[J]. Thorac Cancer, 2018, 9(8): 1032-1040.
|
11 |
Ferguson SW, Nguyen J. Exosomes as therapeutics: The implications of molecular composition and exosomal heterogeneity[J]. J Control Release, 2016, 228: 179-190.
|
12 |
Zheng H, Zhan Y, Liu S, et al. The roles of tumor-derived exosomes in non-small cell lung cancer and their clinical implications[J]. J Exp Clin Cancer Res, 2018, 37(1): 226.
|
13 |
Conde-Vancells J, Rodriguez-Suarez E, Embade N, et al. Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes[J]. J Proteome Res, 2008, 7(12): 5157-5166.
|
14 |
Sun Z, Shi K, Yang S, et al. Effect of exosomal miRNA on cancer biology and clinical applications[J]. Mol Cancer, 2018, 17(1): 147.
|
15 |
Zhou L, Lv T, Zhang Q, et al. The biology, function and clinical implications of exosomes in lung cancer[J]. Cancer Lett, 2017, 407: 84-92.
|
16 |
Rabinowits G, Gercel-Taylor C, Day JM, et al. Exosomal microRNA:a diagnostic marker for lung cancer[J]. Clin Lung Cancer, 2009, 10(1): 42-46.
|
17 |
Sun Z, Shi K, Yang S, et al. Effect of exosomal miRNA on cancer biology and clinical applications[J]. Mol Cancer, 2018, 17(1): 147.
|
18 |
Jin X, Chen Y, Chen H, et al. Evaluation of tumor-derived exosomal miRNA as potential diagnostic biomarkers for early-stage non-small cell lung cancer using next-generation sequencing[J]. Clin Cancer Res, 2017, 23(17): 5311-5319.
|
19 |
Cao C, Sun SF, Lv D, et al. Utility of VEGF and sVEGFR-1 in bronchoalveolar lavage fluid for differential diagnosis of primary lung cancer[J]. Asian Pac J Cancer Prev, 2013, 14(4): 2443-2446.
|
20 |
Coumans F, Brisson AR, Buzas EI, et al. Methodological guidelines to study extracellular vesicles[J]. Circ Res, 2017, 120(10): 1632-1648.
|
21 |
Greider CW, Blackburn EH. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts[J]. Cell, 1985, 43(2 Pt 1): 405-413.
|
22 |
Shekhani MT, Barber JR, Bezerra SM, et al. High-resolution telomere fluorescence in situ hybridization reveals intriguing anomalies in germ cell tumors[J]. Hum Pathol, 2016, 54: 106-112.
|
23 |
Ma F, Wang TT, Jiang L, et al. Ultrasensitive detection of telomerase activity in lung cancer cells with quencher-free molecular beacon-assisted quadratic signal amplification[J]. Anal Chim Acta, 2019, 1053: 122-130.
|
24 |
Dikmen E, Kara M, Dikmen G, et al. Detection of telomerase activity in bronchial lavage as an adjunct to cytological diagnosis in lung cancer[J]. Eur J Cardiothorac Surg, 2003, 23(2): 194-199.
|
25 |
朱育银,叶春娟,方 晴,等. 支气管肺泡灌洗液端粒酶活性测定对113例肺外周孤立结节诊断的临床研究[J]. 临床肺科杂志,2007, 12(12): 1317-1318.
|
26 |
Parks JW, Stone MD. Single-molecule studies of telomeres and telomerase[J]. Annu Rev Biophys, 2017, 46: 357-377.
|
27 |
胡腾惠,徐兴祥. 端粒酶抑制剂对不同非整倍体状态的人结肠癌HCT116细胞增殖及凋亡的影响[J]. 中国细胞生物学学报,2017, 39(4): 426-434.
|
28 |
Beroukhim R, Mermel CH, Porter D, et al. The landscape of somatic copy-number alteration across human cancers[J]. Nature, 2010, 463(7283): 899-905.
|
29 |
Thompson LL, Jeusset LM, Lepage CC, et al. Evolving therapeutic strategies to exploit chromosome instability in cancer [J]. Cancers (Basel), 2017, 9(11): pii: E151.
|
30 |
陶 伟,李 俊,程柳柳. 细胞DNA定量分析技术在肺癌诊断中的应用价值[J]. 中华肿瘤杂志,2016, 38(2): 113-117.
|
31 |
高树庚,汪良骏,张德超,等. 支气管镜刷取细胞染色体异倍性的研究[J]. 中华医学杂志,2002, 82(16): 13-15.
|
32 |
Douville C, Springer S, Kinde I, et al. Detection of aneuploidy in patients with cancer through amplification of long interspersed nucleotide elements (LINEs)[J]. Proc Natl Acad Sci U S A, 2018, 115(8): 1871-1876.
|