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中华肺部疾病杂志(电子版) ›› 2020, Vol. 13 ›› Issue (01) : 104 -106. doi: 10.3877/cma.j.issn.1674-6902.2020.01.026

综述

槲皮素药理学作用的研究进展
刘晟文1, 刘建英1,()   
  1. 1. 563002 贵州,遵义医科大学第三附属医院
  • 收稿日期:2019-08-11 出版日期:2020-02-25
  • 通信作者: 刘建英

Advances in the pharmacological effects of quercetin

Shengwen Liu1, Jianying Liu1()   

  • Received:2019-08-11 Published:2020-02-25
  • Corresponding author: Jianying Liu
引用本文:

刘晟文, 刘建英. 槲皮素药理学作用的研究进展[J]. 中华肺部疾病杂志(电子版), 2020, 13(01): 104-106.

Shengwen Liu, Jianying Liu. Advances in the pharmacological effects of quercetin[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2020, 13(01): 104-106.

1
Granato M, Rizzello C, Gilardini Montani MS, et al. Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways[J]. J Nutr Biochem, 2017, 41: 124-136.
2
Lespade, Laure. Ab initio molecular dynamics of the reaction of quercetin with superoxide radical[J]. Chemical Physics, 2016, 475: 32-38.
3
黄海艳,王 芳,丁晓岚,等. 槲皮素对H2O2诱导的正常人黑素细胞氧化损伤的保护作用[J]. 中国皮肤性病学杂志,2014, 10(3): 1012-1017.
4
Saw CL, Guo Y, Yang AY, et al. The berry constituents quercetin, kaempferol, and pterostilbene synergistically attenuate reactive oxygen species: Involvement of the Nrf2-ARE signaling pathway[J]. Food Chem Toxicol, 2014, 72: 303-311.
5
Wang J, Qian X, Gao Q, et al. Quercetin increases the antioxidant capacity of the ovary in menopausal rats and in ovarian granulosa cell culture in vitro[J]. J Ovarian Res, 2018, 11(1): 51.
6
d′Avila Farias M, Oliveira PS, Dutra FS, et al. Eugenol derivatives as potential anti-oxidants: is phenolic hydroxyl necessary to obtain an effect?[J]. J Pharm Pharmacol, 2014, 66(5): 733-746.
7
Backe MB, Moen IW, Ellervik C, et al. Iron Regulation of Pancreatic Beta-Cell Functions and Oxidative Stress[J]. Annu Rev Nutr, 2016, 36(1): 241-273.
8
Vasconcellos LR, Dutra FF, Siqueira MS, et al. Protein aggregation as a cellular response to oxidative stress induced by heme and iron[J]. Proc Natl Acad Sci U S A, 2016, 113(47): E7474- E7482.
9
Chen Z, Song S, Wen Y, et al. Toxicity of Cu (Ⅱ) to the green alga Chlorella vulgaris : a perspective of photosynthesis and oxidant stress[J]. Environ Sci Pollut Res Int, 2016, 23(18): 17910-17918.
10
Rakshit A, Khatua K, Shanbhag V, et al. Cu2+ selective chelators relieve copper-induced oxidative stress in vivo[J]. Chem Sci, 2018, 9(41): 7916-7930.
11
Tang Y, Li Y, Yu H, et al. Quercetin attenuates ethanol hepatotoxicity by regula ting "free" iron uptake and release[C]. 2012年第二届中韩植物化学物国际学术研讨会.
12
Babenkova IV, Osipov AN, Teselkin YO. The Effect of Dihydroquercetin on Catalytic Activity of Iron (Ⅱ) Ions in the Fenton Reaction[J]. Bull Exp Biol Med, 2018, 165(3): 347-350.
13
PęKal A, Biesaga M, Pyrzynska K. Interaction of quercetin with copper ions: complexation, oxidation and reactivity towards radicals[J]. Biometals, 2011, 24(1): 41-49.
14
Jomova K, Lawson M, Drostinova L, et al. Protective role of quercetin against copper(Ⅱ)-induced oxidative stress: A spectroscopic, theoretical and DNA damage study[J]. Food Chem Toxicol, 2017, 110: 340-350.
15
Beong Ou Lim, Byung Pal Yu, Seong Ⅱ Cho, et al. The inhibition by quercetin and ganhuangenin on oxidatively modified low density lipoprotein[J]. Phytotherapy Research, 2015, 12(5): 340-345.
16
Mbikay M, Sirois F, Simoes S, et al. Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL uptake by Huh7 human hepatocytes in culture[J]. FEBS Open Bio, 2014, 4: 755-762.
17
Lee JY, Park W. Anti-Inflammatory Effect of Wogonin on RAW 264.7 Mouse Macrophages Induced with Polyinosinic-Polycytidylic Acid[J]. Molecules, 2015, 20(4): 6888-6900.
18
Zhang LL, Zhang HT, Cai YQ, et al. Anti-inflammatory Effect of Mesenchymal Stromal Cell Transplantation and Quercetin Treatment in a Rat Model of Experimental Cerebral Ischemia[J]. Cell Mol Neurobiol, 2016, 36(7): 1023-1034.
19
Si TL, Liu Q, Ren YF, et al. Enhanced anti-inflammatory effects of DHA and quercetin in lipopolysaccharide-induced RAW264.7 macrophages by inhibiting NF-κB and MAPK activation[J]. Mol Med Rep, 2016, 14(1): 499-508.
20
Wu W, Li R, Li X, et al. Quercetin as an Antiviral Agent Inhibits Influenza A Virus (IAV) Entry[J]. Viruses, 2016, 8(1): 6.
21
Rojas Á, Del Campo JA, Clement S, et al. Effect of Quercetin on Hepatitis C Virus Life Cycle: From Viral to Host Targets[J]. Sci Rep, 2016, 6(1): 31777.
22
Brito AF Ribeiro M, Abrantes AM, et al. New approach for treatment of primary liver tumors: The role of quercetin[J]. Nutr Cancer, 2016, 68(2): 250-266.
23
Ren KW, Li YH, Wu G, et al. Quercetin nanoparticles display antitumor activity via proliferation inhibition and apoptosis induction in liver cancer cells[J]. Int J Oncol, 2017, 50(4): 1299-1311.
24
Klimaszewska-Wisniewska A, Hasas-Wisniewska M, Izdebska M, et al. Antiproliferative and antimetastatic action of quercetin on A549 non-small cell lung cancer cells through its effect on the cytoskeleton[J]. Acta Histochem, 2017, 119(2): 99-112.
25
Shen X, Si Y, Wang Z, et al. Quercetin inhibits the growth of human gastric cancer stem cells by inducing mitochondrial-dependent apoptosis through the inhibition of PI3K/Akt signaling[J]. Int J Mol Med, 2016, 38(2): 619-626.
26
Yang L, Liu Y, Wang M, et al. Quercetin-induced apoptosis of HT-29 colon cancer cells via inhibition of the Akt-CSN6-Myc signaling axis[J]. Mol Med Rep, 2016, 14(5): 4559-4566.
27
Ahmad M, Sultana M, Raina R, et al. Hypoglycemic, Hypolipidemic,and Wound Healing Potential of Quercetin in Streptozotocin-Induced Diabetic Rats[J]. Pharmacogn Mag, 2017, 13(Suppl 3): S633-S639.
28
Vidyashankar S, Sandeep Varma R, Patki PS. Quercetin ameliorate insulin resistance and up-regulates cellular antioxidants during oleic acid induced hepatic steatosis in HepG2 cells[J]. Toxicol In Vitro, 2013, 27(2): 945-953.
29
Lugli E, Ferraresi R, Roat E, et al. Quercetin inhibits lymphocyte activation and proliferation without inducing apoptosis in peripheral mononuclear cells[J]. Leuk Res, 2009, 33(1): 140-150.
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