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中华肺部疾病杂志(电子版) ›› 2021, Vol. 14 ›› Issue (06) : 830 -832. doi: 10.3877/cma.j.issn.1674-6902.2021.06.036

综述

LAMA4的结构、生物学功能及其与肿瘤关系的研究进展
惠盼1, 谯钰琪1, 南岩东2,()   
  1. 1. 710038 西安,空军军医大学唐都医院呼吸与危重症医学科;716000 延安,延安大学医学院
    2. 710038 西安,空军军医大学唐都医院呼吸与危重症医学科
  • 收稿日期:2021-06-18 出版日期:2021-12-25
  • 通信作者: 南岩东
  • 基金资助:
    陕西省重点研发计划(2019SF-009); 唐都医院创新发展基金(2017LCYJ016)

Research Progress on the structure, biological function and relationship with tumor of lama4

Pan Hui1, Yuqi Qiao1, Yandong Nan2()   

  • Received:2021-06-18 Published:2021-12-25
  • Corresponding author: Yandong Nan
引用本文:

惠盼, 谯钰琪, 南岩东. LAMA4的结构、生物学功能及其与肿瘤关系的研究进展[J]. 中华肺部疾病杂志(电子版), 2021, 14(06): 830-832.

Pan Hui, Yuqi Qiao, Yandong Nan. Research Progress on the structure, biological function and relationship with tumor of lama4[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2021, 14(06): 830-832.

1
Richards AJ, Al-Imara L, Carter NP, et al. Localization of the gene (LAMA4) to chromosome 6q21 and isolation of a partial cDNA encoding a variant laminin A chain[J]. Genomics, 1994, 22(1): 237-239.
2
Simon-Assmann P. The laminin family: founding members of the basement membrane[J]. Cell Adh Migr, 2013, 7(1): 44-47.
3
Richards A, Al-Imara L, Pope FM. The complete cDNA sequence of laminin alpha 4 and its relationship to the other human laminin alpha chains[J]. Eur J Biochem, 1996, 238(3): 813-821.
4
Timpl R, Rohde H, Robey PG, et al. Laminin-a glycoprotein from basement membranes[J]. J Biol Chem, 1979, 254(19): 9933-9937.
5
Yousif LF, Di Russo J, Sorokin L. Laminin isoforms in endothelial and perivascular basement membranes[J]. Cell Adh Migr, 2013, 7(1): 101-110.
6
Domogatskaya A, Rodin S, Tryggvason K. Functional diversity of laminins[J]. Annu Rev Cell Dev Biol, 2012, 28: 523-553.
7
Qin Y, Rodin S, Simonson OE, et al. Laminins and cancer stem cells: Partners in crime?[J]. Semin Cancer Biol, 2017, 45: 3-12.
8
Carmona-Rodriguez L, Martinez-Rey D, Mira E, et al. SOD3 boosts T cell infiltration by normalizing the tumor endothelium and inducing laminin-alpha4[J]. Oncoimmunology, 2020, 9(1): 1794163.
9
Vainionpaa N, Lehto VP, Tryggvason K, et al. Alpha4 chain laminins are widely expressed in renal cell carcinomas and have a de-adhesive function[J]. Lab Invest, 2007, 87(8): 780-791.
10
Maltseva DV, Rodin SA. [Laminins in Metastatic Cancer][J]. Mol Biol (Mosk), 2018, 52(3): 411-434.
11
Li Y, Guan B, Liu J, et al. MicroRNA-200b is downregulated and suppresses metastasis by targeting LAMA4 in renal cell carcinoma[J]. EBio Med, 2019, 44: 439-451.
12
Wang X, Hou Q, Zhou X. LAMA4 expression is activated by zinc finger Eboxbinding homeobox 1 and independently predicts poor overall survival in gastric cancer[J]. Oncol Rep, 2018, 40(3): 1725-1733.
13
Peng L, Li Y, Wei S, et al. LAMA4 activated by Androgen receptor induces the cisplatin resistance in gastric cancer[J]. Biomed Pharmacother, 2020, 124: 109667.
14
马丽萍,刘小林,张哲雄,等. LAMA4通过TGF-β1/SMAD路径调控肝癌细胞免疫逃逸因子及促进肝癌细胞凋亡[J]. 免疫学杂志2019, 35(4): 300-307.
15
Liu AG, Pang YY, Chen G, et al. Downregulation of miR-199a-3p in Hepatocellular Carcinoma and Its Relevant Molecular Mechanism via GEO, TCGA Database and In Silico Analyses[J]. Technol Cancer Res Treat, 2020,19: 1079247318.
16
Zhao W, Han HB, Zhang ZQ. Suppression of lung cancer cell invasion and metastasis by connexin43 involves the secretion of follistatin-like 1 mediated via histone acetylation[J]. Int J Biochem Cell Biol, 2011, 43(10): 1459-1468.
17
Speisky D, Ddces A, Niccoli P, et al. Molecular profiling of pancreatic neuroendocrine tumors in sporadic and von hippel-lindau patients[J]. Clin Cancer Res, 2012, 18(10): 2838-2849.
18
Zheng B, Qu J, Ohuchida K, et al. LAMA4 upregulation is associated with high liver metastasis potential and poor survival outcome of pancreatic cancer[J]. Theranostics, 2020, 10(22): 10274-10289.
19
Wang M, Li C, Liu Y, et al. Effect of LAMA4 on Prognosis and its correlation with immune infiltration in gastric cancer[J]. Biomed Res Int, 2021, 2021: 6428873.
20
Mal′Tseva DV, Makarova YA, Raigorodskaya MP, et al. Effects of laminins 332 and 411 on the epithelial-mesenchymal status of colorectal cancer cells[J]. Bull Exp Biol Med, 2019, 166(3): 377-382.
21
Galatenko VV, Maltseva DV, Galatenko AV, et al. Cumulative prognostic power of laminin genes in colorectal cancer[J]. BMC Med Genomics, 2018, 11(Suppl 1): 9.
22
Kohata T, Ito S, Masuda T, et al. Laminin subunit Alpha-4 and osteopontin are glioblastoma-selective secreted proteins that are increased in the cerebrospinal fluid of glioblastoma patients[J]. J Proteome Res, 2020,19(8): 3542-3553.
23
Ljubimova JY, Lakhter AJ, Loksh A, et al. Overexpression of alpha4 chain-containing laminins in human glial tumors identified by gene microarray analysis[J]. Cancer Res, 2001, 61(14): 5601-5610.
24
Zhou J, Su M, Zhang H, et al. miR-539-3P inhibits proliferation and invasion of gastric cancer cells by targeting CTBP1[J]. Int J Clin Exp Pathol, 2019, 12(5): 1618-1625.
25
Shkurnikov M, Nikulin S, Nersisyan S, et al. LAMA4-Regulating miR-4274 and its host gene SORCS2 play a role in IGFBP6-dependent effects on phenotype of basal-like breast cancer[J]. Front Mol Biosci, 2019, 6: 122.
26
Yang H, Huo P, Hu G, et al. Identification of gene markers associated with metastasis in clear cell renal cell carcinoma[J]. Oncol Lett, 2017, 13(6): 4755-4761.
27
Huang X, Ji G, Wu Y, et al. LAMA4, highly expressed in human hepatocellular carcinoma from Chinese patients, is a novel marker of tumor invasion and metastasis[J]. J Cancer Res Clin Oncol, 2008, 134(6): 705-714.
28
Shkurnikov MY, Maltseva DV, Knyazev EN, et al. [Expression of stroma components in the lymph nodes affected by prostate cancer metastases][J]. Mol Biol (Mosk), 2018, 52(5): 810-816.
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