分析原发性结节肿块型肺黏液腺癌的CT表现、随访变化，以提高对本病的认识。

分析80例经病理证实的原发性结节肿块型肺黏液腺癌患者的病理、临床及影像资料。患者均行胸部CT检查，其中57例患者行胸部CT平扫+增强检查，8例有间隔时间2周以上的随访CT。分析病灶影像学征象及动态CT随访变化。

微浸润肺黏液腺癌7例，浸润性肺黏液腺癌73例。单发病灶78例，多原发病灶2例。混杂磨玻璃结节20例，实性病灶60例。69例(86.2%)位于胸膜下，49例(61.2%)位于肺下叶。占比50%以上的征象有：类圆形46例、瘤肺界面清楚毛糙45例，分叶征70例、磨玻璃征43例。平扫病灶密度均低于肌肉，轻度强化19例，中度强化30例，明显强化8例，17例病灶内可见无强化的液性区域，血管造影征15例。CT动态随访变化多样，可短期保持稳定或迅速增长，或短期内实性成分减少而磨玻璃成分增多，或长期保持不变或缓慢增长。

原发性结节肿块型肺黏液腺癌好发于双肺下叶及胸膜下，多呈类圆形、瘤肺界面清楚毛糙，多伴有分叶征及磨玻璃征，以轻中度强化为主。CT动态随访变化多样。结合病灶的HRCT征象、CT增强及随访变化对诊断肺黏液腺癌有一定意义。

To explore the CT findings, follow-up changes of primary nodular mass pulmonary mucinous adenocarcinoma, so as to improve the understanding of the disease.

The pathological, clinical and imaging data of 80 patients with primary nodular mass lung mucinous adenocarcinoma confirmed by pathology were retrospectively analyzed. All patients underwent chest CT examination, of which 57 patients underwent enhanced chest CT examination, and 8 patients had follow-up CT with more than 2 weeks interval. Analyze the imaging signs and dynamic CT follow-up changes of the lesions.

There were 7 cases of minimally invasive pulmonary mucinous adenocarcinoma and 73 cases of invasive pulmonary mucinous adenocarcinoma. There were 78 cases with a single lesion and 2 cases with multiple primary lesions. There were 20 cases of mixed ground glass nodules and 60 cases of solid lesions. 69 cases (86.2%) were located under the pleura and 49 cases (61.2%) were located in the lower lobe of the lung.These features accounted for more than 50% of all CT signs in 80 cases, including round shape in 46 cases(57.5%), clear and rough interface in 45 cases(56.2%), lobulation in 70 cases(87.5%), ground-glass opacity sign in 43 cases(53.8%). The density of lesions on non-enhanced CT was lower than that of muscle. There were 19 cases with mild enhancement, 30 cases with moderate enhancement, 8 case with obvious enhancement, 17 cases with non-enhanced liquid areas, and 15 cases with angiographic signs. CT dynamic follow-up changes are diverse, which can remain stable or grow rapidly in the short term, or the solid component will decrease and the ground glass component will increase in the short term, or remain unchanged or grow slowly for a long time.

Primary nodular-mass type pulmonary mucinous adenocarcinoma usually occurs in the lower lobes of the lungs and under the pleura. It is mostly round-shaped, and the tumor-lung interface is clear and rough, often accompanied by lobular signs and ground glass signs. Mainly with mild to moderate enhancement degree .CT dynamic follow-up changes are diverse. Combining the HRCT signs, CT enhancement and follow-up changes of the lesions has certain suggestive significance for the diagnosis of lung mucinous adenocarcinoma.