切换至 "中华医学电子期刊资源库"

中华肺部疾病杂志(电子版) ›› 2022, Vol. 15 ›› Issue (02) : 276 -278. doi: 10.3877/cma.j.issn.1674-6902.2022.02.038

综述

环状RNA在肺动脉高压发病机制中的研究进展
杨益1, 黄秋红1, 尤再春1,()   
  1. 1. 400037 重庆,陆军(第三)军医大学第二附属医院全科医学科
  • 收稿日期:2021-10-05 出版日期:2022-04-25
  • 通信作者: 尤再春
  • 基金资助:
    国家自然科学基金资助项目(81873413); 重庆市自然科学基金(cstc2018jcyjAX0098)

Research progress of circrnas in the pathogenesis of pulmonary hypertension

Yi Yang1, Qiuhong Huang1, Zaichun You1()   

  • Received:2021-10-05 Published:2022-04-25
  • Corresponding author: Zaichun You
引用本文:

杨益, 黄秋红, 尤再春. 环状RNA在肺动脉高压发病机制中的研究进展[J/OL]. 中华肺部疾病杂志(电子版), 2022, 15(02): 276-278.

Yi Yang, Qiuhong Huang, Zaichun You. Research progress of circrnas in the pathogenesis of pulmonary hypertension[J/OL]. Chinese Journal of Lung Diseases(Electronic Edition), 2022, 15(02): 276-278.

1
Hoeper MM, Humbert M, Souza R, et al. A global view of pulmonary hypertension[J]. Lancet Respir Med, 2016, 4(4): 306-322.
2
Sommer N, Ghofrani H A, Pak O, et al. Current and future treatments of pulmonary arterial hypertension[J]. Br J Pharmacol, 2021, 178(1): 6-30.
3
Jeck WR, Sorrentino JA, Wang K, et al. Circular RNAs are abundant, conserved, and associated with ALU repeats[J]. RNA, 2013, 19(2): 141-157.
4
Verduci L, Tarcitano E, Strano S, et al. CircRNAs: role in human diseases and potential use as biomarkers[J]. Cell Death Dis, 2021, 12(5): 1-12.
5
Kelly S, Greenman C, Cook PR, et al. Exon skipping is correlated with exon circularization[J]. J Mol Biol, 2015, 427(15): 2414-2417.
6
Ma S, Kong S, Wang F, et al. CircRNAs: biogenesis, functions, and role in drug-resistant Tumours[J]. Mol Cancer, 2020, 19(1): 1-19.
7
Eidem TM, Kugel JF, Goodrich JA. Noncoding RNAs: regulators of the mammalian transcription machinery[J]. J Mol Biol, 2016, 428(12): 2652-2659.
8
Liang ZZ, Guo C, Zou MM, et al. CircRNA-miRNA-mRNA regulatory network in human lung cancer: an update[J]. Cancer Cell Int, 2020, 20(1): 1-16.
9
Kramer MC, Liang D, Tatomer DC, et al. Combinatorial control of drosophila circular RNA expression by intronic repeats, hnRNPs, and SR proteins[J]. Genes Dev, 2015, 29(20): 2168-2182.
10
Aktas T, Avsar Ilik I, Maticzka D, et al. DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome[J]. Nature, 2017, 544(7648): 115-119.
11
Rong D, Sun H, Li Z, et al. An emerging function of circRNA-miRNAs-mRNA axis in human diseases[J]. Oncotarget, 2017, 8(42): 73271-73281.
12
Chen LL. The expanding regulatory mechanisms and cellular functions of circular RNAs[J]. Nat Rev Mol Cell Biol, 2020, 21(8): 475-490.
13
Huang A, Zheng H, Wu Z, et al. Circular RNA-protein interactions:functions, mechanisms, and identification[J]. Theranostics, 2020, 10(8): 3503-3517.
14
Zang J, Lu D, Xu A. The interaction of circRNAs and RNA binding proteins: An important part of circRNA maintenance and function[J]. J Neurosci Res, 2020, 98(1): 87-97.
15
Shi Y, Jia X, Xu J. The new function of circRNA: translation[J]. Clin Transl Oncol, 2020, 22(12): 2162-2169.
16
Southgate L, Machado RD, Graf S, et al. Molecular genetic framework underlying pulmonary arterial hypertension[J]. Nat Rev Cardiol, 2020, 17(2): 85-95.
17
Li R, Jiang J, Shi H, et al. CircRNA: a rising star in gastric cancer[J]. Cell Mol Life Sci, 2020, 77(9): 1661-1680.
18
Zaiou M. CircRNAs signature as potential diagnostic and prognostic biomarker for diabetes mellitus and related cardiovascular complications[J]. Cells, 2020, 9(3):1-19.
19
Wang J, Zhao X, Wang Y, et al. CircRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma[J]. Cell Death Dis, 2020, 11(1): 1-11.
20
Wang Y, Zhao R, Liu W, et al. Exosomal circHIPK3 released from hypoxia-pretreated cardiomyocytes regulates oxidative damage in cardiac microvascular endothelial cells via the miR-29a/IGF-1 pathway[J]. Oxid Med Cell Longev, 2019, 2019: 7954657.
21
Zhang J, Li Y, Qi J, et al. Circ-calm4 Serves as an miR-337-3p sponge to regulate Myo10 (Myosin 10) and promote pulmonary artery smooth muscle proliferation[J]. Hypertension, 2020, 75(3): 668-679.
22
Yang L, Liang H, Meng X, et al. Mmu_circ_0000790 is involved in pulmonary vascular remodeling in mice with HPH via microRNA-374c-mediated FOXC1[J]. Mol Ther Nucleic Acids, 2020, 20: 292-307.
23
Wang J, Zhu MC, Kalionis B, et al. Characteristics of circular RNA expression in lung tissues from mice with hypoxiainduced pulmonary hypertension[J]. Int J Mol Med, 2018, 42(3): 1353-1366.
24
Zhou S, Jiang H, Li M, et al. Circular RNA hsa_circ_0016070 is Associated with pulmonary arterial hypertension by promoting PASMC proliferation[J]. Mol Ther Nucleic Acids, 2019, 18: 275-284.
25
Jin X, Xu Y, Guo M, et al. Hsa_circNFXL1_009 modulates apoptosis, proliferation, migration, and potassium channel activation in pulmonary hypertension[J]. Mol Ther Nucleic Acids, 2021, 23: 1007-1019.
26
Ma C, Gu R, Wang X, et al. CircRNA CDR1as promotes pulmonary artery smooth muscle cell calcification by upregulating CAMK2D and CNN3 via sponging miR-7-5p[J]. Mol Ther Nucleic Acids, 2020, 22: 530-541.
27
Li Y, Zheng Q, Bao C, et al. Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis[J]. Cell Res, 2015, 25(8): 981-984.
28
Guo J, Zhang L, Lian L, et al. CircATP2B4 promotes hypoxia-induced proliferation and migration of pulmonary arterial smooth muscle cells via the miR-223/ATR axis[J]. Life sciences, 2020, 262: 1-9.
29
Miao R, Gong J, Zhang C, et al. Hsa_circ_0046159 is involved in the development of chronic thromboembolic pulmonary hypertension[J]. J Thromb Thrombolysis, 2020, 49(3): 386-394.
30
Dang RY, Liu FL, Li Y. Circular RNA hsa_circ_0010729 regulates vascular endothelial cell proliferation and apoptosis by targeting the miR-186/HIF-1alpha axis[J]. Biochem Biophys Res Commun, 2017, 490(2): 104-110.
31
Hong L, Ma X, Liu J, et al. Circular RNA-HIPK3 regulates human pulmonary artery endothelial cells function and vessel growth by regulating microRNA-328-3p/STAT3 axis[J]. Pulm Circ, 2021, 11(2): 1-11.
32
Liu W, Wang Y, Qiu Z, et al. CircHIPK3 regulates cardiac fibroblast proliferation, migration and phenotypic switching through the miR-152-3p/TGF-beta2 axis under hypoxia[J]. PeerJ, 2020, 8: 1-19.
33
Shan K, Liu C, Liu B H, et al. Circular noncoding RNA HIPK3 mediates retinal vascular dysfunction in diabetes mellitus[J]. Circulation, 2017, 136(17): 1629-1642.
34
Li Q, Tian Y, Liang Y, et al. CircHIPK3/miR-876-5p/PIK3R1 axis regulates regulation proliferation, migration, invasion, and glutaminolysis in gastric cancer cells[J]. Cancer Cell Int, 2020, 20: 1-12.
[1] 杨桂清, 孟静静. 哺乳期亚临床乳腺炎的研究进展[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 376-379.
[2] 吴义刚, 潘裕民, 吴姗姗, 胡梦涓, 王一为, 张劲松, 乔莉. 左西孟旦治疗肺动脉高压合并右心衰竭患者疗效分析——Meta 分析[J/OL]. 中华危重症医学杂志(电子版), 2024, 17(05): 385-391.
[3] 吕军好, 林锦雯, 张心怡, 陈江华. 细胞外囊泡在肾移植诊断和治疗中的研究进展[J/OL]. 中华移植杂志(电子版), 2024, 18(03): 186-192.
[4] 刘中文, 刘畅, 高洋, 刘东, 林世庆, 杨建华, 赵福义. 尿液microRNA-326与腹腔镜根治性膀胱切除术治疗膀胱癌患者预后的相关性研究[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2024, 18(04): 386-391.
[5] 宋新雅, 苏小慧, 卞士柱, 丁小涵. 吸入性药物治疗肺动脉高压的研究进展[J/OL]. 中华肺部疾病杂志(电子版), 2024, 17(05): 831-835.
[6] 罗霞, 王宝梅, 李淑景, 杨英. 特发性肺动脉高压血清PCSK9表达及预后意义[J/OL]. 中华肺部疾病杂志(电子版), 2024, 17(04): 585-589.
[7] 甘志新, 胡雍军, 肖晶, 胡明冬. 降钙素原在脓毒血症与肺部感染中的研究进展[J/OL]. 中华肺部疾病杂志(电子版), 2024, 17(04): 663-666.
[8] 曾聿理, 雷发容, 肖慧, 邱德亮, 谢静, 吴寻. 氯普鲁卡因通过调控circRNA-ZKSCAN1表达抑制肝癌Huh-7细胞体外生长和转移的研究[J/OL]. 中华细胞与干细胞杂志(电子版), 2024, 14(04): 220-228.
[9] 董晓斌, 张静, 苏莎莎, 莎比亚·沙吾提, 盛好. 溃疡性结肠炎患者相关环状RNA 差异表达谱分析及功能研究[J/OL]. 中华结直肠疾病电子杂志, 2024, 13(06): 499-509.
[10] 季鹏程, 鄂一民, 陆晨, 喻春钊. 循环外泌体相关生物标志物在结直肠癌诊断中的研究进展[J/OL]. 中华结直肠疾病电子杂志, 2024, 13(04): 265-273.
[11] 冯熔熔, 苏晓乐, 王利华. 慢性肾脏病患者并发心血管疾病相关生物标志物研究进展[J/OL]. 中华肾病研究电子杂志, 2024, 13(05): 273-278.
[12] 张晓青, 唐雯. 基于临床化验指标重新计算的生物标记物在预测腹膜透析患者预后中的作用研究进展[J/OL]. 中华肾病研究电子杂志, 2024, 13(04): 213-218.
[13] 潘冬生, 梁国标. 颅脑创伤治疗的最新进展与未来趋势[J/OL]. 中华神经创伤外科电子杂志, 2024, 10(04): 193-197.
[14] 王江波, 尹一鸣, 张冠群. 外周血生物标志物在阿尔茨海默病早期诊断中的价值[J/OL]. 中华脑科疾病与康复杂志(电子版), 2024, 14(04): 244-249.
[15] 贾玲玲, 滕飞, 常键, 黄福, 刘剑萍. 心肺康复在各种疾病中应用的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(09): 859-862.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?