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中华肺部疾病杂志(电子版) ›› 2023, Vol. 16 ›› Issue (04) : 592 -595. doi: 10.3877/cma.j.issn.1674-6902.2023.04.040

短篇论著

有氧运动对成人哮喘肺功能、生活质量以及哮喘控制影响的Meta分析
刘佳铭, 孙晓容(), 文健, 何晓丽, 任茂玲   
  1. 400037 重庆,陆军(第三)军医大学第二附属医院呼吸与危重症医学科
  • 收稿日期:2023-02-17 出版日期:2023-08-25
  • 通信作者: 孙晓容

Meta-analysis of the effects of aerobic exercise on lung function, quality of life and asthma control in adults with asthma

Jiaming Liu, Xiaorong Sun(), Jian Wen   

  • Received:2023-02-17 Published:2023-08-25
  • Corresponding author: Xiaorong Sun
引用本文:

刘佳铭, 孙晓容, 文健, 何晓丽, 任茂玲. 有氧运动对成人哮喘肺功能、生活质量以及哮喘控制影响的Meta分析[J]. 中华肺部疾病杂志(电子版), 2023, 16(04): 592-595.

Jiaming Liu, Xiaorong Sun, Jian Wen. Meta-analysis of the effects of aerobic exercise on lung function, quality of life and asthma control in adults with asthma[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2023, 16(04): 592-595.

支气管哮喘是最常见的慢性疾病之一,全球哮喘倡议指南(Guidelines for the Global Asthma Initiative, GINA)将其定义为一种异质性疾病,以慢性气道炎症和气道高反应性为主要特点,并伴有不同程度的气流受限反复发作[1,2],其作为全球常见多发病,患病率不断上升,WHO估计,全世界有2.35~2.5亿人受到哮喘的影响[3,4]。尽管药物治疗取得了进展,但哮喘控制不力导致了大量患者就诊和住院,并降低了生活质量。有氧运动被证实对健康人群会产生实质性的益处[5],规律的有氧运动可以提高患者的心肺功能[5,6]但对于哮喘患者而言,常常会引起哮喘症状发作,因此许多患者会对运动产生抗拒。本文分析有氧运动对成人哮喘的肺功能、生活质量以及哮喘控制的影响,报道如下。

图1 文献偏倚风险评价
表1 检索11篇文献基本特征
纳入研究 分组 例数 男/女 年龄 干预方式 结局指标
Dogra S.2010 有氧 12 3/9 31.2±4.2 30 min/次,5次/周,持续12周 肺功能(FEV1/FVC%)、AQLQ
  对照 12 3/9 34.0±3.4 无干预,保持生活习惯  
Franca-Pinto A.2015 有氧 22 5/17 40.0±17.0 呼吸训练+有氧锻炼(35 min/次,2次/周,持续12周) 肺功能(FEV1,FEV1%)、AQLQ、ACQ
  对照 21 4/17 44.0±9.0 呼吸训练  
Freitas PD.2021 有氧 25 5/20 46.4±10.1 90 min/次,1次/周,持续8周 ACQ、AQLQ
  对照 26 3/23 45.9±9.4 常规护理  
Dogra S.2011 有氧 18 5/13 34.2±3.2 35 min/次,3次/周,持续12周 肺功能(FEV1/FVC%、FEV1%)、AQLQ
  对照 12 3/9 34.0±3.4 无干预,维持目前生活习惯  
Scott HA.2013 有氧 13 6/7 33.9±11.5 饮食干预+有氧锻炼(1 h/次,3次/周,持续12周) 肺功能(FEV1/FVC%、FEV1%)、AQLQ、ACQ
  对照 15 7/8 44.7±14.7 饮食干预  
Hiles SA.2021 有氧 15 6/9 67.0±9.0 瑜伽(每周75 min,持续16周) 肺功能(FEV1%)
  对照 9 4/5 68.0±8.0 常规护理  
Mendes FA.2011 有氧 27 3/24 37.9±12.6 呼吸训练+有氧锻炼(30 min/次,2次/周,持续3个月) 肺功能(FEV1/FVC%、FEV1%)
  对照 24 6/18 36.0±13.4 呼吸训练  
Mendes FA.2010 有氧 44 5/39 39.0±17.9 呼吸训练+有氧锻炼(30 min/次,2次/周,持续3个月) 肺功能(FEV1、FEV1/FVC%、FEV1%)
  对照 45 10/35 39.5±16.0 呼吸训练  
Freitas PD.2017 有氧 28 3/25 45.9±7.7 2次/周,持续3个月 肺功能(FEV1)、AQLQ
  对照 27 2/25 48.5±9.6 假性运动(伸展和呼吸)  
Vempati R.2009 有氧 29 13/16 33.5±11.4 瑜伽(4 h/次,1次/日,持续8周) 肺功能(FEV1/FVC%、FEV1%)、AQLQ
  对照 28 20/8 33.4±11.5 常规护理  
Toennesen LL.2018 有氧 29 16/13 39.4±12.5 饮食干预+有氧锻炼(1 h/次,3次/周,持续8周) 肺功能(FEV1)、AQLQ、ACQ
  对照 34 8/26 38.2±12.7 饮食干预  
图2 漏斗图
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