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中华肺部疾病杂志(电子版) ›› 2023, Vol. 16 ›› Issue (05) : 739 -741. doi: 10.3877/cma.j.issn.1674-6902.2023.05.038

综述

肺癌自身抗体在肺癌诊断中的研究进展
高嘉营, 金发光()   
  1. 710038 西安,空军军医大学第二附属医院呼吸与危重症医学科
  • 收稿日期:2023-04-02 出版日期:2023-10-25
  • 通信作者: 金发光

Research progress of lung cancer autoantibodies in lung cancer diagnosis

Jiaying Gao, Faguang Jin()   

  • Received:2023-04-02 Published:2023-10-25
  • Corresponding author: Faguang Jin
引用本文:

高嘉营, 金发光. 肺癌自身抗体在肺癌诊断中的研究进展[J]. 中华肺部疾病杂志(电子版), 2023, 16(05): 739-741.

Jiaying Gao, Faguang Jin. Research progress of lung cancer autoantibodies in lung cancer diagnosis[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2023, 16(05): 739-741.

肺癌作为最常见的一种恶性肿瘤疾病,严重影响人类健康[1]。肺癌在男性群体中的患病率位于第一位,在女性群体中肺癌患病率位居第三位,排在乳腺癌、大肠癌之后。肺癌男性患者的患病率与病死率是女性的两倍之多[2]。到2018年,我国就有新增加肺癌患者77.4万例,其中有69万例患者死亡是肺癌所导致。Ⅰ期肺癌患者5年的生存率是77.0%~92.0%,而Ⅳ期患者5年的生存率不满10%[3,4]。虽然分子检测技术的进步大大提高了诊断和治疗水平,但大约85%的肺癌是在中晚期阶段发现,此时失去了最佳治疗时机,导致肺癌的总生存率仍然很低。进一步开发无创、重复性较好,具备较高灵敏度与高特异度的生物标志物用于早期肺癌的辅助诊断,是临床的重点工作,从而达到肺癌早期发现,早期治疗的目的,以此提高肺癌患者的长期生存率,这对于提高肺癌的诊治水平是很有必要的。

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