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中华肺部疾病杂志(电子版) ›› 2025, Vol. 18 ›› Issue (01) : 176 -179. doi: 10.3877/cma.j.issn.1674-6902.2025.01.033

综述

多模态超声引导消融治疗周围型肺癌研究进展
夏永旭1, 林元强1, 王辉1   
  1. 1. 130000 长春,吉林大学中日联谊医院超声科
  • 收稿日期:2024-12-05 出版日期:2025-02-25
  • 基金资助:
    吉林省卫生科研人才专项项目(2023SCZ59)

Research progress of multimodal ultrasound-guided ablation in the treatment of peripheral lung cancer

Yongxu Xia, Yuanqiang Lin, Hui Wang   

  • Received:2024-12-05 Published:2025-02-25
引用本文:

夏永旭, 林元强, 王辉. 多模态超声引导消融治疗周围型肺癌研究进展[J/OL]. 中华肺部疾病杂志(电子版), 2025, 18(01): 176-179.

Yongxu Xia, Yuanqiang Lin, Hui Wang. Research progress of multimodal ultrasound-guided ablation in the treatment of peripheral lung cancer[J/OL]. Chinese Journal of Lung Diseases(Electronic Edition), 2025, 18(01): 176-179.

多模态超声引导消融治疗周围型肺癌通过整合二维/三维超声、弹性成像及靶向超声造影技术,提升了肿瘤定位与疗效监测的精准性。 人工智能(artificial intelligence,AI)辅助图像分割、4D超声呼吸门控系统及双极射频消融技术的应用,优化了消融范围与安全性。 多模态超声引导消融治疗对早期周围型肺癌的3 年无进展生存率与手术切除相当,并发症发生率低。 电磁导航超声(electromagnetic navigation ultrasound,EMN-US)联合正电子发射断层显像/X 线计算机体层成像(positron emission tomography/computedtomography,PET/CT)影像融合技术,降低消融针定位误差,低功率脉冲消融方案可减少肺功能损伤。 未来多模态超声引导消融治疗主要发展方向为智能化(AI 实时规划消融路径)、多模态影像融合(超声-CT/MRI)及个性化治疗(基于基因组学)。 远程5G 操控系统已实现亚毫米级动物实验消融,为基层医疗提供新可能。 多模态超声引导消融治疗通过技术创新与临床实践,为周围型肺癌提供了精准、安全的替代方案,未来有望成为早期肺癌的一线治疗选择。

1
汤少鹏.不同肺段切割术在全胸腔镜手术治疗早期周围型肺癌患者中的应用效果分析[J].实用癌症杂志,2023,38(9):1522-1525.
2
Wu X,Uhlig J,Blasberg JD,et al.Microwave ablation versus stereotactic body radiotherapy for stage I non-small cell lung cancer:A cost-effectiveness analysis[J].J Vascul Int Radiol,2022,33(8): 964-971.
3
侯振国,李永才,高凤霄,等.双能量CT 在晚期非小细胞肺癌放化疗近期疗效评估中的价值[J].实用放射学杂志,2022,38(1): 38-41.
4
Liu J,Wang C,Yi W,et al.A retrospective comparative study of microwave ablation and sublobectomy in the treatment of early subpleural nonsmall cell lung cancer[J].Int J Hypertherm,2022,39(1): 1379-1386.
5
Ni Y,Peng J,Yang X,et al.Multicentre study of microwave ablation for pulmonary oligorecurrence after radical resection of nonsmall-cell lung cancer[J].British J Cancer,2021,125: 672-678.
6
梁汝娜,王 娟,张 伟,等.超声造影与高分辨率CT 鉴别诊断周围型肺肿物的价值[J].中国CT 和MRI 杂志,2023,21(3): 68-70.
7
李朝密,郑 慧,姚 文,等.三维斑点追踪成像技术评价化疗对肺癌患者心肌收缩功能的影响[J].安徽医科大学学报,2016,51(2): 243-246.
8
Verhoeven RL,Trisolini R,Leoncini F ,et al.Predictive value of endobronchial ultrasound strain elastography in mediastinal lymph node staging:the e-predict multicenter study results[J].Respiration,2020,99(6):1-9.
9
Xu L,Guo J,Qi S,et al.Development and validation of a nomogram model for the prediction of 4L lymph node metastasis in thoracic esophageal squamous cell carcinoma[J].Front Oncol,2022,12:887047.
10
Mohan A,Madan K,Hadda V,et al.Guidelines for endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA): Joint Indian Chest Society (ICS)/Indian Association for Bronchology(IAB) recommendations[J].Lung India,2023,40(4):368-400.
11
Wang Y,Zhao Z,Zhu M,et al.Diagnostic value of endobronchial ultrasound elastography in differentiating between benign and malignant hilar and mediastinal lymph nodes: a retrospective study[J].Quant Imaging Med Surg,2023,13(7): 4648-4662.
12
黄 鑫,陈文卫,孙 彬,等.肺癌肝转移瘤超声造影表现与病理组织类型的对照研究[J].中华超声影像学杂志,2020,29(7): 602-607.
13
吴 鹏,张 璇,肖海燕,等.超声造影引导下肺活检对周围型肺癌的诊断价值[J].微创医学,2018,13(3): 289-292.
14
McGahan JP,Gu WZ,Brock JM,et al.Hepatic ablation usingbiopolar rdiofrequency electrocautery [J].Acad Radiol,1996,3: 418-422.
15
张贻庆,崔贵医,杨 磊,等.肝肿瘤切除术与射频消融术治疗原发性肝癌的疗效及其对血清AFP,CEA,CA125 水平的影响[J].实用癌症杂志,2022,27(8): 1316-1319.
16
Kong FL,Bie ZX,Li YM,et al.Synchronous microwave ablation followed by core-needle biopsy via a coaxial cannula for highly suspected malignant lung ground-glass opacities: A single-center,single-arm retrospective study[J].Thoracic Cancer,2021,12(23):3216-3222.
17
Wang N,Xue T,Zheng W,et al.Safety and efficacy of percutaneous biopsy and microwave ablation in patients with pulmonary nodules on antithrombotic therapy: A study with rivaroxaban bridging [J].Thorac Cancer,2024,15(28): 1989-1999.
18
王 丽.中国原发性肺癌诊疗规范(2015 年版)[J].中华肿瘤杂志,2016,37(7): 433-436.
19
樊 啸,张驰豪,夏 焱.射频消融与手术切除治疗肿瘤最大径≤5 cm 孤立性肝细胞癌的疗效比较[J].肝胆胰外科杂志,2022,34(4): 198-204.
20
高振森,黄 进,李丹丹,等.超声CT 引导多点布针单极冷循环射频消融治疗周围型肺癌的对比研究[J].中国超声医学杂志,2013,29(10): 882-886.
21
刘 涛,郭晨凡,吴 鲧.多次微波消融治疗复发转移性肺癌1例并文献复习[J].中国临床研究,2023,36(10): 1577-1579.
22
莫伶丽,田福年,莫金霖,等.多模态超声引导下经皮微波消融术治疗甲状腺良性结节的疗效与安全性分析[J].广西医科大学学报,2017,34(1): 86-90.
23
Ishiwata T,Motooka Y,Ujiie H,et al.Endobronchial ultrasoundguided bipolar radiofrequency ablation for lung cancer: A first-inhuman clinical trial[J].J Thoracic Cardiovascul Surg,2022,164(4): 1188-1197.
24
姜 华,金发光.肺小结节消融的现状与争议[J/CD].中华肺部疾病杂志(电子版),2024,17(3): 493-496.
25
李大伟,周振堰,熊 星,等.CT 引导下经皮穿刺微波消融术对周围型肺癌患者的临床疗效及安全性[J].影像研究与医学应用,2024,8(20): 171-173.
26
李吉燮.微波消融治疗周围型肺癌的近期临床效果[J].中国卫生标准管理,2021,12(17): 67-71.
27
Guo JY,Zhao LL,Cai HJ,et al.Radiofrequency ablation combined with transcatheter arterial chemoembolization for recurrent liver cancer[J].World J Gastrointest Surg,2024,16(6): 1756-1764.
28
Hassanin TM,Fouad Y,Hassnine A,et al.Quality of life after transcatheterarterialchemoembolizationcombinedwith radiofrequency ablation in patients with unresectable hepatocellular carcinoma compared with transcatheter arterial chemoembolization alone[J].Asian Pac J Cancer Prev,2021,22(4): 1255-1261.
29
Yu Y,Fu J,Xia P,et al.A systematic review and meta-analysis on the efficacy and safety of transcatheter arterial chemoembolization combined with radiofrequency ablation in the treatment of primary liver cancer[J].Transl Cancer Res,2022,11(5): 1297-1308.
30
Jiang C,Cheng G,Liao M,et al.Individual or combined transcatheter arterial chemoembolization and radiofrequency ablation for hepatocellular carcinoma: a time-to-event meta-analysis[J].World J Surg Oncol,2021,19(1): 81.
31
Tian Z,Hu Q,Sun ZCW.A booster for radiofrequency ablation:advanced adjuvant therapy via in situ nanovaccine synergized with anti-programmed death ligand 1 immunotherapy for systemically constraining hepatocellular carcinoma[J].ACS Nano,2023,17(19): 19441-19458.
32
Wang Z,Miao F,Gu L,et al.Stimulator of interferon genesactivated biomimetic dendritic cell nanovaccine as a chemotherapeutic booster to enhance systemic fibrosarcoma treatment[J].ACS Nano,2024,18(35): 24219-24235.
33
Ao F,Li X,Tan Y,et al.STING agonist-based hydrogel enhances immune activation in synergy with radiofrequency ablation for hepatocellular carcinoma treatment[J].J Control Release,2024,369: 296-308.
34
Lu YF,Zhou JP,Zhou QM,et al.Ultra-thin layered double hydroxidemediated photothermal therapy combine with asynchronous blockade of PD-L1 and NR2F6 inhibit hepatocellular carcinoma [ J].J Nanobiotechnology,2022,20(1): 351.
35
Chockalingam A,Konstantinidis M,Koo B,et al.Surgical resection,radiotherapy and percutaneous thermal ablation for treatment of stage 1 non-small cell lung cancer: protocol for a systematic review and network meta-analysis[J].BMJ Open,2022,12(6): e057638.
36
Crider K,Williams J,Qi YP,et al.Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas[J].Cochrane Database Syst Rev,2022,2(2022): CD014217.
37
Wade R,South E,Anwer S,et al.Ablative and non-surgical therapies for early and very early hepatocellular carcinoma: a systematic review and network meta-analysis[J].Health Technol Assess,2023,27(29): 1-172.
38
Huang X,Chen Q,Ren Y,et al.Three-dimensional conformal radiation therapy with concurrent chemotherapy for stage Ⅲnonsmall cell lung cancer: protocol for a systematic review and metaanalysis[J].BMJ Open,2024,14(11): e090728.
39
Dumbrique JIS,Hernandez RB,Cruz JML,et al.Pneumothorax detection and segmentation from chest X-ray radiographs using a patch-based fully convolutional encoder-decoder network[J].Front Radiol,2024,4: 1424065.
40
Harriet Evans,David Snead.Understanding the errors made by artificial intelligence algorithms in histopathology in terms of patient impact[J].NPJ Digit Med,2024,7(1): 89.
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