To study the morbidity and mortality of co-morbidity and complications in patients with chronic obstructive pulmonary disease (COPD).

1 210 hospitalized patients with COPD were collected in Department of Respiratory and Critical Care Medicine Center from January 2018 to December 2018 in this study, and they were divided three groups, including COPD group, co-morbidity group and complication group. Meanwhile, the morbidity and mortality were observed, then, compared to different of the sex, age, course, smoking, the number of acute exacerbations per year, and mortality in the three groups.

The morbidity rate of co-morbidity/complications were 98.60%, and the mortality rate was 1.34%, which was significantly increasing than that of the control group(P<0.05). In the analysis of morbidity, the results indicated that the morbidity of cardiovascular diseases was significantly higher than other system disease, which was 36.37%. Secondly, the lung cancer was the highest in COPD with pulmonary disease, also 36.37%. Next, the respiratory failure was most rate in complications, was 20.95%. Otherwise, In the analysis of mortality, results shown that it was high mortality rate in COPD with cardiovascular system diseases, nervous system diseases, blood system diseases, respiratory failure, pulmonary encephalopathy, it was 4.25%, 4.28%, 5.00%, 3.60%, 6.25%. Moreover, there was markedly increasing in course and the number of acute exacerbations per year in co-morbidity/complications group compared to COPD group. Finally, In the analysis of morbidity and mortality in different classification, the result found that the morbidity of hypertension was highest, at 25.81%, however, the mortality of upper gastrointestinal hemorrhage was highest in all diseases, was 16.66%.

The morbidity and mortality of COPD patients with complications are higher, which seriously influenced the treatment and prognosis of disease. Therefore, the co-morbidity and complications of COPD should be paid more attention in clinical work.