To construct a column chart prediction model for obstructive sleep apnea-hypopnea syndrome complicated with pulmonary hypertension and analyze its predictive value.

A total of 127 patients with obstructive sleep apnea-hypopnea syndrome admitted to our hospital from July 2021 to February 2023 were selected as the study objects, 92 patients with simple obstructive sleep apnea-hypopnea syndrome were selected as the control group, and 35 patients with obstructive sleep apnea-hypopnea syndrome complicated with pulmonary hypertension were selected as the observers. The risk factors of obstructive sleep apnea-hypopnea syndrome complicated with pulmonary hypertension were analyzed, and the linear prediction model of obstructive sleep apnea-hypopnea syndrome complicated with pulmonary hypertension was constructed.

Patients with obstructive sleep apnea-hypopnea syndrome complicated with pulmonary hypertension have a history of underlying diseases, a proportion of recent history of acute bacterial infection, NLR, PLR, CRP, RDW, ET-1 levels, and higher levels of nitrite, SpO₂, cardiac output and NO level were relatively low (P<0.05). Multivariate logistic regression analysis showed that recent acute bacterial infection history [OR(95%CI): 4.815 (3.580-6.052)], NLR [OR(95%CI): 3.284 (2.362-4.206)], PLR[OR(95%CI): 5.124 (23.942-6.306)], CRP[OR(95%CI): 3.688 (2.754-4.622)], RDW[OR(95%CI): 4.129 (3.377-4.881)], nitrite [OR(95%CI): 4.958 (3.766-6.150)], SpO₂[OR(95%CI): 5.607(4.471-6.743)], cardiac output [OR(95%CI): 4.116(3.390-4.842)]], NO[OR(95%CI): 4.968(3.832-6.104)] and ET-1[OR(95%CI): 5.228(4.108-6.348)] were the main factors affecting obstructive sleep apnea-hypopnea syndrome complicated with pulmonary hypertension (P<0.05). Based on recent history of acute bacterial infection, NLR, PLR, CRP, RDW, nitrite, SpO₂, cardiac output, NO, and ET 110 independent risk factors, a column-line prediction model for obstructive sleep apnea-hypopnea syndrome complicated with pulmonary hypertension was drawn using a column-line online website. The sensitivity, specificity, accuracy, area under the curve and 95%CI of the prediction model for obstructive sleep apnea-hypopnea syndrome complicated with pulmonary hypertension were 91.47%, 92.68%, 91.81% and 0.921(0.882-0.960), respectively.

Recent history of acute bacterial infection, NLR, PLR, CRP, RDW, nitrite, SpO₂, cardiac output, NO and ET-1 are all associated with obstructive sleep apnea-hypopnea syndrome complicated with pulmonary hypertension. The prediction model based on the above indexes can effectively predict obstructive sleep apnea-hypopnea syndrome complicated with pulmonary hypertension.