Analysis of consistency between ultrasound-guided pleural biopsy and medical thoracoscopy pleural biopsy in diagnosis

doi:10.3877/cma.j.issn.1674-6902.2024.02.003

Abstract

Abstract:

Objective

The clinical data of patients with pleural effusion by ultrasound guided pleural biopsy (USPB) and medical thoracoscopic pleural biopsy (MTPB) were retrospectively analyzed, to explore the selection and diagnostic consistency of these two sampling methods.

Methods

74 patients with pleural effusion by USPB and MTPB were recruited in the Department of Respiratory and Critical Care Medicine of our hospital from October 2020 to May 2023. The general clinical data, pleural effusion characteristics, sample quality, and pathological diagnostic value were analyzed.

Results

The pathological diagnostic value of patients who underwent USPB before undergoing MTPB (USPB+ MTPB group) 40 cases was not superior to those who directly underwent MTPB (MTPB group)34 cases, and the difference was statistically significant (P=0.007). Among the 40 patients in the USPB+ MTPB group, the sample sizes of USPB and MTPB were 0.004 (0.003, 0.011) mm³ and 0.105 (0.026, 0.230) mm^3, with statistically significant differences (P<0.001); the pathological diagnostic value of USPB is not superior to that of MTPB, and the difference is statistically significant (P<0.001). The positive rates of USPB and MTPB were 65.00% and 95.00%, respectively; the negative rates were 35.00% and 5.00%, respectively. The reliability evaluation index Kappa value of USPB and MTPB is 0.038.

Conclusion

MTPB is superior to USPB in terms of positive diagnostic rate, sample quality, and pathological diagnostic value. Clinicians should also consider patient individualization, safety, and accessibility when selecting the two.

Key words: Pleural effusion, Ultrasound guided pleural biopsy, Medical thoracoscopy pleural biopsy

Hongjun Zhang, Xing Gu, Yanjun Zhao, Yaqin Chai, Wenjie Li, Pei Shi, Haitao Zhang. Analysis of consistency between ultrasound-guided pleural biopsy and medical thoracoscopy pleural biopsy in diagnosis[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2024, 17(02): 185-188.

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References 20

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临床资料	变量	USPB组	MTPB组	检验值	P值
标本大小[V, M(Q₁，Q₃)]	体积(mm³)	0.004(0.003，0.011)	0.105(0.026，0.230)	5.448	0.000
病理诊断价值(等级)	A	0	2(5.00)
	B	3(7.50)	14(35.00)	16.099	0.000
	C	23(57.50)	22(55.00)
	D	14(35.00)	2(5.00)

临床资料	变量	USPB组	MTPB组	检验值	P值
标本大小[V, M(Q₁，Q₃)]	体积(mm³)	0.004(0.003，0.011)	0.105(0.026，0.230)	5.448	0.000
病理诊断价值(等级)	A	0	2(5.00)
	B	3(7.50)	14(35.00)	16.099	0.000
	C	23(57.50)	22(55.00)
	D	14(35.00)	2(5.00)

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