Analysis of association between prestroke albumin and risk of pneumonia

doi:10.3877/cma.j.issn.1674-6902.2024.04.030

Abstract

Yi Zhang, Yuyang Wang, Mengjiao Si. Analysis of association between prestroke albumin and risk of pneumonia[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2024, 17(04): 648-651.

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临床资料		对照组(n＝90)	观察组(n＝23)	统计值	P值
既往史	高血压	49(54.44)	15(65.22)	0.866	0.352
	高脂血症	24(26.67)	11(47.83)	3.836	0.050
	糖尿病	13(14.44)	5(21.74)	0.728	0.394
	房颤	7(7.78)	5(21.74)	3.762	0.052
	心力衰竭	2(2.22)	1(4.35)	0.320	0.571
吸烟		47(52.22)	15(65.22)	1.249	0.264
NIHSS评分	0～4	44(48.89)	10(43.48)	2.902	0.4075
	～9	35(38.89)	7(30.43)
	10～14	8(8.89)	4(17.39)
	≥15	3(3.33)	2(8.70)
GCS评分	3～8	13(14.44)	9(39.13)	8.065	0.0189
	～12	28(31.11)	3(13.04)
	13～15	49(54.44)	11(47.83)
OCSP分型	完全前循环梗死	24(26.67)	6(26.09)	0.774	0.856
	部分前循环梗死	32(35.56)	7(30.43)
	后循环梗死	21(23.33)	5(21.74)
	腔隙性梗死	13(14.44)	5(21.74)
脑卒中后吞咽功能障碍		15(16.67)	11(47.83)	10.040	0.002
随机血糖(mmol/L)		5.00±1.32	6.17±1.40	3.618	0.001
白细胞计数(×10⁹/L)		6.89±2.00	8.54±2.34	3.104	0.004
中性粒细胞计数(×10⁹/L)		4.09±0.89	4.95±1.38	2.842	0.009
淋巴细胞计数(×10⁹/L)		1.89±0.46	1.63±0.45	2.462	0.019
血小板计数(×10⁹/L)		231.12±60.84	227.82±62.17	0.228	0.821
hS-CRP		5.07±0.76	6.10±1.62	2.967	0.007
纤维蛋白原		3.48±1.13	3.83±1.24	1.229	0.228
前白蛋白(mg/L)		290.52±81.82	243.26±81.56	2.478	0.018
白蛋白(g/L)		41.11±3.42	39.46±4.10	1.778	0.085

临床资料		对照组(n＝90)	观察组(n＝23)	统计值	P值
既往史	高血压	49(54.44)	15(65.22)	0.866	0.352
	高脂血症	24(26.67)	11(47.83)	3.836	0.050
	糖尿病	13(14.44)	5(21.74)	0.728	0.394
	房颤	7(7.78)	5(21.74)	3.762	0.052
	心力衰竭	2(2.22)	1(4.35)	0.320	0.571
吸烟		47(52.22)	15(65.22)	1.249	0.264
NIHSS评分	0～4	44(48.89)	10(43.48)	2.902	0.4075
	～9	35(38.89)	7(30.43)
	10～14	8(8.89)	4(17.39)
	≥15	3(3.33)	2(8.70)
GCS评分	3～8	13(14.44)	9(39.13)	8.065	0.0189
	～12	28(31.11)	3(13.04)
	13～15	49(54.44)	11(47.83)
OCSP分型	完全前循环梗死	24(26.67)	6(26.09)	0.774	0.856
	部分前循环梗死	32(35.56)	7(30.43)
	后循环梗死	21(23.33)	5(21.74)
	腔隙性梗死	13(14.44)	5(21.74)
脑卒中后吞咽功能障碍		15(16.67)	11(47.83)	10.040	0.002
随机血糖(mmol/L)		5.00±1.32	6.17±1.40	3.618	0.001
白细胞计数(×10⁹/L)		6.89±2.00	8.54±2.34	3.104	0.004
中性粒细胞计数(×10⁹/L)		4.09±0.89	4.95±1.38	2.842	0.009
淋巴细胞计数(×10⁹/L)		1.89±0.46	1.63±0.45	2.462	0.019
血小板计数(×10⁹/L)		231.12±60.84	227.82±62.17	0.228	0.821
hS-CRP		5.07±0.76	6.10±1.62	2.967	0.007
纤维蛋白原		3.48±1.13	3.83±1.24	1.229	0.228
前白蛋白(mg/L)		290.52±81.82	243.26±81.56	2.478	0.018
白蛋白(g/L)		41.11±3.42	39.46±4.10	1.778	0.085

影响因素	β	S.E	Wald χ ²	df	P值	OR	95%CI
影响因素	β	S.E	Wald χ ²	df	P值	OR	下限	上限
GCS评分(以3～8分为参照)			6.298	2	0.043
GCS评分(1＝9～12分，0＝非9～12分)	－2.599	1.26	4.256	1	0.039	0.074	0.006	0.878
GCS评分(2＝13～15，0＝非13～15分)	－5.14	2.095	6.017	1	0.014	0.006	0.001	0.356
脑卒中后吞咽功能障碍	2.877	1.386	4.311	1	0.038	17.768	1.175	268.723
随机血糖	0.620	0.421	2.169	1	0.141	1.859	0.814	4.245
白细胞计数	1.098	0.435	6.374	1	0.012	2.998	1.278	7.031
中性粒细胞计数	1.433	0.517	7.675	1	0.006	4.191	1.521	11.549
淋巴细胞计数	－4.509	1.868	5.825	1	0.016	0.011	0.001	0.429
hS-CRP	0.803	0.262	9.384	1	0.002	2.233	1.336	3.733
前白蛋白	－0.040	0.018	4.947	1	0.026	0.960	0.927	0.995
常数	－22.715	9.325	5.934	1	0.015	0.000

影响因素	β	S.E	Wald χ ²	df	P值	OR	95%CI
影响因素	β	S.E	Wald χ ²	df	P值	OR	下限	上限
GCS评分(以3～8分为参照)			6.298	2	0.043
GCS评分(1＝9～12分，0＝非9～12分)	－2.599	1.26	4.256	1	0.039	0.074	0.006	0.878
GCS评分(2＝13～15，0＝非13～15分)	－5.14	2.095	6.017	1	0.014	0.006	0.001	0.356
脑卒中后吞咽功能障碍	2.877	1.386	4.311	1	0.038	17.768	1.175	268.723
随机血糖	0.620	0.421	2.169	1	0.141	1.859	0.814	4.245
白细胞计数	1.098	0.435	6.374	1	0.012	2.998	1.278	7.031
中性粒细胞计数	1.433	0.517	7.675	1	0.006	4.191	1.521	11.549
淋巴细胞计数	－4.509	1.868	5.825	1	0.016	0.011	0.001	0.429
hS-CRP	0.803	0.262	9.384	1	0.002	2.233	1.336	3.733
前白蛋白	－0.040	0.018	4.947	1	0.026	0.960	0.927	0.995
常数	－22.715	9.325	5.934	1	0.015	0.000

影响因素	AUC	S.E	95%CI		敏感度(%)	特异度(%)	截点值
影响因素	AUC	S.E	下限	上限	敏感度(%)	特异度(%)	截点值
脑卒中后吞咽功能障碍	0.705	0.056	0.612	0.787	56.52	84.44	/
白细胞计数	0.709	0.069	0.560	0.742	65.22	70.00	7.5
中性粒细胞计数	0.727	0.007	0.635	0.806	56.52	83.33	4.4
淋巴细胞计数	0.688	0.065	0.574	0.754	52.17	76.67	1.7
前白蛋白	0.715	0.058	0.622	0.796	57.83	87.78	257
hS-CRP	0.723	0.053	0.631	0.820	63.82	89.42	5.7

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