To analyze the risk factors of moderate to severe acute pain after thoracoscopic segmental resection of the lung in patients with bronchogenic lung cancer.

Seventy-two patients with acute pain after thoracoscopic segmental resection of bronchogenic lung cancer and a pain duration of more than 20 minutes who were admitted to our hospital from August 2022 to August 2024 were selected as the subjects. The severity of acute pain was determined by the visual analogue scale (VAS). Eighteen cases with a score of 4 to 10 were classified as the moderate to severe group, and 54 cases with a score of 1 to 3 were classified as the mild group. The age, gender, smoking history, drinking history, educational level, diabetes, hypertension, preoperative anxiety, preoperative depression, preoperative fear score (Fear of Pain Questionnaire-Ⅲ-FPQ-Ⅲ), history of chest and back pain, and TNM stage (Ⅰ, Ⅱ, Ⅲ) were compared between the two groups Stage A), surgery and postoperative conditions (American Society of Anesthesiologists classification, operation time, surgical site, days of postoperative analgesia, number of closed thoracic drainage tubes, days of closed thoracic drainage tubes, postoperative hospital stay, anesthesia time, consumption of analgesic drugs within 7 days after surgery, presence or absence of complications), Logistic regression was used to analyze the factors of moderate to severe acute pain after surgery.

The results of multivariate analysis indicated that the history of alcohol consumption (OR=2.038, 95%CI: 1.345~3.088), preoperative anxiety (OR=2.375, 95%CI: 1.314~4.293), and preoperative fear score (OR=1.923, 95%CI: 1.414~2.616), diameter (OR=2.625, 95%CI: 1.595~4.318), operation time (OR=2.421, 95%CI: 1.184~4.950), postoperative hospital stay (OR=2.237, 95%CI: 1.660~3.013), anesthesia time (OR=2.136, 95%CI: 1.139~4.007), postoperative analgesia method (intercostal nerve resistance) (OR=0.521, 95%CI: 0.312~0.871), incision intercostal space width (≥1.5 cm) (OR=0.470, 95%CI: 0.285~0.772) is an influencing factor for moderate to severe acute pain in patients after bronchogenic lung cancer surgery (P<0.05).

Factors such as drinking history, preoperative anxiety, preoperative fear score, diameter, and operation time are risk factors for moderate to severe acute pain after thoracoscopic segmental resection of bronchogenic lung cancer. Early identification and treatment are helpful to reduce the incidence of moderate to severe acute pain after surgery and improve the quality of life after surgery.