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Chinese Journal of Lung Diseases(Electronic Edition) ›› 2019, Vol. 12 ›› Issue (04): 458-462. doi: 10.3877/cma.j.issn.1674-6902.2019.04.011

• Original Article • Previous Articles     Next Articles

Clinical effect and prognosis of probiotics in treatment of senile pneumonia

Ming Hu1,(), Xiaoli Li1, Peng Zhen1, Yali Chen1, Baozheng Shen1   

  1. 1. Department of Infectious Diseases, Beijing Luhe Hospital, Capital Medical University, Tongzhou 101100, China
  • Received:2018-07-10 Online:2019-08-20 Published:2021-07-19
  • Contact: Ming Hu

Abstract:

Objective

To explore the clinical effect and prognosis of probiotics in the treatment of senile pneumonia.

Methods

From August 2016 to August 2018, 124 elderly patients with pneumonia admitted to our hospital were selected as the research objects. They were divided into two groups according to the simple random method. The control group was given standard treatment of pneumonia, while the observation group was given standard treatment of pneumonia plus probiotics. The occurrence of diarrhea, fecal pH value, hospitalization time, therapeutic effect, bacterial imbalance, fungal infection, respiratory tract infection and fever were compared between the two groups before and after treatment.

Results

The incidence of diarrhea and the fecal pH value in the observation group were lower than those in the control group (P<0.05). The average periods of hospital stay were (14.62±3.69) days in the control group and (10.35±3.11) days in the observation group, which had statistical significant difference (P<0.05). The effective rates of treatment were 75.00% in the control group and 90.00% in the observation group, which had significant difference (P<0.05). The smear of the two groups before treatment showed that the ratio of bacteria to the ball was ≥3︰1, the total number of bacteria was 501-5 000 per oil field vision, and no fungal infection was found. Dysbacteriosis occurred in the two groups during hospitalization and within 30 days after discharge, however, the incidence was lower in the observation group than in the control group (P<0.05). The incidence of fungal infection in the observation group was lower than that in the control group within 30 days after discharge (P<0.05). The patients in the two groups were followed up for 30 days. In the control group, there were 16 cases of respiratory infection and 14 cases of fever. In the observation group, there were 7 cases of respiratory infection and 4 cases of fever. The incidence of respiratory infection and fever in the observation group was lower than that of the control group, which had statistical significant difference (P<0.05).

Conclusion

The application of probiotics in the treatment of senile pneumonia can improve the therapeutic effect, reduce the occurrence of diarrhea and dysbacteriosis, shorten the hospitalization time and improve the prognosis.

Key words: Probiotics, Elderly pneumonia, Therapeutic effect, Prognosis

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