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Chinese Journal of Lung Diseases(Electronic Edition) ›› 2020, Vol. 13 ›› Issue (02): 229-235. doi: 10.3877/cma.j.issn.1674-6902.2020.02.021

• Original Article • Previous Articles     Next Articles

Effects of different air pollutants on the outpatient quantity of respiratory diseases

Luyao Han1, Kejian Wu2, Yongheng Gao1, Gaole Yu1, Zhichao Li3, Zaiqiang Wang1, Yanjun Gao1, Hongwei Lin1, Faguang Jin1,()   

  1. 1. Department of Respiratory, Second Affiliated Hospital, Air Force Medical University, Xi′an 710038, China
    2. Department of Mathematics and Physics, School of Basic Medicine, Air Force Medical University, Xi′an 710038, China
    3. Department of physiology and pathophysiology, Air Force Medical University, Xi′an 710038, China
  • Received:2019-12-21 Online:2020-04-25 Published:2021-07-22
  • Contact: Faguang Jin

Abstract:

Objective

To explore the effects of different air pollutants on the outpatient quantity of respiratory diseases, with the city of xi′an as the research object.

Methods

collected relevant data, including the daily data of six kinds of air pollutants in Xi′an from 2015 to 2016 (PM2.5 and PM10, CO, SO2, NO2 and O3), the daily meteorological data in Xi′an from 2015 to 2016 (average temperature, daily average relative humidity and daily average air pressure, wind speed), and the daily outpatient and emergency data of respiratory departments of two comprehensive 3A grade hospitals in Xi′an during the same period. Spearman′s rank correlation test was used to evaluate the correlation between air pollutants and meteorological factors during the same period. A smooth spline function was used to control the influence of daily mean temperature, relative humidity, air pressure and long-term trend on the outpatient volume of respiratory diseases. The Day of the Week effect (DOW) was incorporated into the multivariate regression model as a dummy variable. Considering the lag effect of 0 to 7 days, this paper adopted the Generalized Additive Model (GAM) taking Poisson distribution as the connection function.Through the construction of single pollutant models and the analysis of age and disease subgroups, the influence of air pollutants on the number of outpatient and emergency visits of respiratory diseases were studied. This paper explained the specific effect of air pollutants on population health in Xi′an.

Results

This study showed that for every 10 μg/m3 increase in the concentration of PM2.5 in xi′an, the emergency department volume of respiratory diseases increased by 0.39% (ER=0.39, 95%CI: 0.37~0.41, P<0.05), and the strongest effect was achieved on the 6th day. For every 10 μg/m3 increase in concentration of PM10, the emergency department volume of respiratory diseases in xi′an increased by 0.34% (ER=0.34, 95%CI: 0.32~0.35, P<0.05). For every 10 mg/m3 increase in concentration of CO, e emergency department volume of respiratory diseases increased by 48.53%(ER=48.53, 95%CI: 46.07~51.03, P<0.05), and the strongest effect was at day 6.For every 10 μg/m3 increase in concentration of NO2, the emergency department volume of respiratory diseases in xi′an increased by 0.96% (ER=0.96, 95%CI: 0.9~1.02, P<0.05). For every 10 μg/m3 increase in the concentration of SO2, the emergency department volume of respiratory system in xi′an increased by 2.13% (ER=2.13, 95%CI: 2.04~2.23, P<0.05). For every 10 μg/m3 increase in the concentration of O3, the emergency department volume of respiratory diseases in xi′an increased by 0.07% (ER=0.07, 95%CI: 0.04~0.10, P<0.05). The increase of the concentrations of PM2.5, PM10, CO, SO2, NO2 and O3 will all cause an increase in the outpatient volume of respiratory diseases, and the effect is the biggest on the 6th day of lag. The effect of CO on the outpatient volume of respiratory system is particularly obvious.

Conclusion

The results of this study showed that exposure to the concentration of six major air pollutants in xi′an would increase the number of outpatient visits for respiratory diseases, among which pollutant CO had the greatest impact on the number of outpatient visits.

Key words: Air pollution, Respiratory disease, Generalized additive model, Time series

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