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Chinese Journal of Lung Diseases(Electronic Edition) ›› 2020, Vol. 13 ›› Issue (06): 746-750. doi: 10.3877/cma.j.issn.1674-6902.2020.06.006

• Original Article • Previous Articles     Next Articles

Clinical characteristics and risk factors of chronic obstructive pulmonary disease complicated with hypertension

Meiju Wang1, Mingdong Hu2, Huaping Chen2, Jing Xu1,(), Shuanglin Liu1, Gang Liu1, Wenjing Zhang1, Xi Liu1, Yuding Jiao1, Shichen Liu1, Qin Wang3, Qi Li1,()   

  1. 1. Department of Respiratory and Critical Care Medicine Center, the Second Affiliated Hospital of Army Medical University, Chongqing 400037, China
    2. Department of Respiratory and Critical Care Medicine Center, the Second Affiliated Hospital of Army Medical University, Chongqing 400037, China; Department of Gerontology and Secret Service Medicine, the Second Affiliated Hospital of Army Medical University, Chongqing 400037, China
    3. Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
  • Received:2020-08-17 Online:2020-12-25 Published:2021-07-27
  • Contact: Jing Xu, Qi Li

Abstract:

Objective

To explore the clinical characteristics of chronic obstructive pulmonary disease (COPD) with hypertension, and analyze the risk factors.

Methods

One hundred twenty-two patients with COPD and hypertension were collected from department of respiratory and critical care medicine center of Xinqiao Hospital from January 2016 to December 2018, and observed their clinical characteristics. Meanwhile, 40 COPD patients as control group, the risk factors were analyzed by multi factor Logistic regression.

Results

Among 122 COPD patients with hypertension, 29.41% were complicated with coronary heart disease, 22.99% with renal disease and diabetes, 21.39% with pulmonary heart disease, 14.97% with cerebral infarction, 4.28% with angina pectoris, 4.28% with myocardial infarction and 9.63% with other cardiovascular diseases. The age of patients with coronary heart disease, myocardial infarction and other cardiovascular diseases was significantly higher than that of COPD patients with hypertension (P<0.05); the disease course of with cor pulmonale was remarkably longer than that of control group (P<0.05); the number of acute exacerbations with coronary heart disease, diabetes, cerebral infarction, angina pectoris and myocardial infarction was obviously more than that in the control group (P<0.05); the hospitalization time of patients with angina pectoris and other cardiovascular diseases was significantly longer compared with control group (P<0.05). Logistic regression analysis showed that over 80 years old, smoking more than 700 per year, drinking, C-reactive protein (CRP) more than 50 mg/L, B-type brain natriuretic peptide(BNP) more than 100 ng/L, hyperglycemia were the risk factors of COPD with hypertension.

Conclusion

COPD complicated with hypertension often caused other related diseases and aggravated the disease. Therefore, it is necessary to pay attention to risk factors as early as possible, which will improve the prognosis of patients.

Key words: Chronic obstructive pulmonary disease, Hypertension, Complications, Risk factors

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