To explore the clinical characteristics and analyze the risk factors in chronic obstructive pulmonary disease (COPD) with tuberculosis.

1 210 COPD cases were collected of department of respiratory and critical care medicine of Xinqiao Hospital all COPD cases in January 2016 to December 2018, and 22 COPD cases without other disease as control from January 2016 to December 2018. Meanwhile, the clinical characteristics and risk factors were analyzed by multi factor Logistic regression.

120 COPD with tuberculosis cases were found, which the morbidity and prevalence rate were 9.91% and 1.67%. In the investigation of co-morbidities, the result showed that lung cancer, Pulmonary infection, pulmonary heart disease, hypertension, coronary heart disease, respiratory failure, diabetes were major diseases, the prevalence rate of them was 20%, 18.33%, 17.50%, 15.83%, 12.5%, 12.5%, 5.83%, respectively. In the study of related factors, the result indicated that number of acute exacerbation was remarkably higher in experimental group than control groups (P<0.05). Nevertheless, there was no significant difference in age, sex, course, smoking rate and smoking time between the two groups (P>0.05). In the logistic regression analysis, the results showed that COPD course over 10 years, number of acute exacerbation over 2 times per year and hypoproteinemia were the risk factors for COPD with tuberculosis.

It is easy to be complicated with other diseases in COPD complicated with tuberculosis, which increases the difficulty of diagnosis and treatment to some extent. Therefore, it is necessary to pay attention to the risk factors for the treatment and prognosis.