Abstract:

Objective

To explore the effectiveness of using 3D reconstruction technology to guide single port thoracoscopic wedge resection for the treatment of pulmonary ground glass nodules ≤2 cm.

Methods

A total of 69 patients with ground glass nodules measuring ≤2 cm，who received surgical treatment in hospitals between January 2021 and June 2024，were enrolled in the study. These patients were divided into two groups based on the treatment method：37 patients in the observation group and 32 patients in the control group. The control group underwent single port thoracoscopic wedge resection，while the observation group underwent single port thoracoscopic wedge resection under the guidance of three-dimensional reconstruction technology. Compare the surgical indicators，stress indicators ［cortisol，norepinephrine，and heat stress protein（HSP） 70］，postoperative lung function ［forced expiratory volume in the first second （FEV₁），maximum ventilation volume （MVV），and residual gas volume］，postoperative pain level，and incidence of complications between the two groups.

Results

The observation group had shorter surgical time，intraoperative blood loss，postoperative 24-hour chest drainage volume，and chest drainage tube retention time compared to the control group （P＜0.05）. After surgery，serum cortisol，norepinephrine，and HSP70 levels increased in both groups compared to preoperative levels，with the observation group being lower than the control group （P＜0.05）. On postoperative day 1，72 hours，and 1 week，the pain scores of both groups gradually decreased （P＜0.05），with the observation group being lower than the control group （P＜0.05）. After surgery，FEV1 and MVV decreased in both groups，with the observation group being higher than the control group （P＜0.05）； The residual gas volume of both groups increased，and the observation group was lower than the control group （P＜0.05）. On postoperative day 1，72 hours，and 1 week，the pain scores of both groups gradually decreased （P＜0.05），with the observation group being lower than the control group （P ＜0.05）. There was no statistically significant difference in the total incidence of pleural effusion，pulmonary leakage，subcutaneous hematoma，and pneumothorax between the two groups （P＞0.05）. The 1-year cumulative survival rate of two groups has statistically significant.

Conclusion

Guided by three-dimensional reconstruction technology，single port thoracoscopic wedge resection is used to treat pulmonary ground glass nodules ≤2 cm，which helps to shorten the surgical time and postoperative recovery time less traumatic stress，reduce postoperative lung function damage，and minimize the occurrence of postoperative complications.

Key words: Pulmonary ground glass nodules, Wedge resection of the lung, Single hole thoracoscopy, 3D reconstruction technology