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中华肺部疾病杂志(电子版) ›› 2017, Vol. 10 ›› Issue (04) : 391 -394. doi: 10.3877/cma.j.issn.1674-6902.2017.04.002

所属专题: 经典病例 文献

论著

50例胸腔巨大肿瘤的外科治疗分析
郭楠楠1, 周少华1, 张文1, 刘阳2,()   
  1. 1. 100048 北京,中国人民解放军总医院第一附属医院胸心外科
    2. 100853 北京,中国人民解放军总医院胸外科
  • 收稿日期:2017-05-24 出版日期:2017-08-20
  • 通信作者: 刘阳
  • 基金资助:
    国家自然科学基金资助项目(81573026)

Surgical treatment of thoracic giant tumor: a report of 50 cases

Nannan Guo1, Shaohua Zhou1, Wen Zhang1, Yang Liu2,()   

  1. 1. Department of Cardiothoracic Surgery, the First Affiliated Hospital of General Hospital of the Chinese People′s Liberation Army, Beijing 100048, China
    2. Department of Thoracic Surgery, General Hospital of PLA, Beijing 100853, China
  • Received:2017-05-24 Published:2017-08-20
  • Corresponding author: Yang Liu
  • About author:
    Corresponding author: Liu Yang, Email:
引用本文:

郭楠楠, 周少华, 张文, 刘阳. 50例胸腔巨大肿瘤的外科治疗分析[J]. 中华肺部疾病杂志(电子版), 2017, 10(04): 391-394.

Nannan Guo, Shaohua Zhou, Wen Zhang, Yang Liu. Surgical treatment of thoracic giant tumor: a report of 50 cases[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2017, 10(04): 391-394.

目的

探讨胸腔巨大肿瘤外科手术治疗以及术中、术后特殊疑难问题的处理经验。

方法

回顾分析2010年1月至2013年6月在中国人民解放军总医院第一附属医院胸心外科手术治疗的50例胸腔巨大肿瘤患者的临床资料。

结果

完整切除肿瘤43例,大部切除肿瘤7例,单纯肿瘤切除46例,联合上腔静脉、无名静脉成形术1例,肺切除3例;正中切口纵劈胸骨8例,胸部侧切口39例,单侧胸部侧切口+横断胸骨切口1例,单侧胸部侧切口+横断锁骨切口1例,颈部横切口1例;切除肿瘤重628~2 586 g,平均1 973 g,术中出血400~1 500 ml。采用预防复张性肺水肿措施后术后并发肺水肿2例,其中1例因合并DIC死亡,1例治愈出院;其余患者术后均治愈出院。

结论

胸腔巨大肿瘤患者往往症状较重,内科保守治疗效果差,手术能彻底改善症状;手术切口要以接近瘤体、同时便于伸延为原则,要充分显露术野;术中可采用完整、分块、大部切除等手术技巧,注意术中避免大出血;术后尽早采用预防复发性肺水肿措施。

Objective

To explore the surgical treatment of thoracic giant tumor and study the special treatment experience for the interoperate and postoperative process.

Methods

Data of 50 thoracic giant tumor cases (26 male and 24 female)hospitalized from January 2010 to June 2013 in Department of Cardiothoracic Surgery, the First Affiliated Hospital of General Hospital of the Chinese People′s Liberation Army was analyzed retrospectively. The patients vary in age from 0.5 to 77.

Results

All 43 tumors were resected completely, the others were subtotal resected. The operation procedures were simple tumor resection in 46 cases, combined superior vena cava and innominate vein angioplasty in 1 case and pulmonary resection in 3 cases. Operation approaches were median longitudinal sternum incision in 8 cases, lateral thoracotomy approach in 39 cases, unilateral chest incision with transverse sternum incision in 1 case, unilateral chest incision with transverse clavicle incision in 1 case, neck transverse incision in 1 case. The weight of the tumors ranged from 628 to 2 586 gram. Bleeding ranged from 400-1500 ml. No postoperative death was observed but only one patient died to DIC caused by reexpansin pulmonary edema.

Conclusions

The thoracic giant tumor cases always accompany with severe symptoms. Surgery is effective for conservative treatment in the aspect of relieving symptoms. The principle of choosing the approach is to operate close to the tumor and to facilitate the extension of operation. Both Integrity excision and subtotal excision are acceptable. Avoiding bleeding during operation and taking measures for prevention of recurrent pulmonary edema are vital.

表1 胸腔巨大肿瘤患者临床资料(n=50)
1
Behera D, Samal A. Multiple organs metastatic mesothelioma in a white tiger[J]. Vet World, 2012, 5(9): 568-570.
2
Welter S, Theegarten D, Trarbach T, et al. Safety distance in the resection of colorectal lung metastases:a prospective evaluation of satellite tumor cells with immunohistochemistry[J]. J Thorac Cardiovasc Surg, 2011, 141(5): 1218-1222.
3
Caudle AS, Ross MI. Metastasectomy for stage IV melanoma: for whom and how much?[J]. Surg Oncol Clin N Am, 2011, 20(1): 133-144.
4
Davis RD, Oldham HN, Sabisston DC. Primary cysts and neoplasms of the mediastinum: recent changes in clinical pretation, methods of diagnosis, management and results[J]. Ann Thorac Surg, 1987, 44(3): 229-237.
5
Shoji S, Usui Y, Nakano M, et al. Surgical management of metastatic adrenal tumors: Decision-making factors in imaging[J]. Oncol Lett, 2010, 1(6): 967-971.
6
Fraga JC, Rothenberg S, Kiely E, et al. Video-assisted thoracic surgery resection for pediatric mediastinal neurogenic tumors[J]. J Pediatr Surg, 2012, 47(7): 1349-1353.
7
Paik KY. Paraganglioma of the pancreas metastasized to the adrenal gland: a case report[J]. Korean J Gastroenterol, 2009, 54(6): 409-412.
8
Balwierz W. Management strategy in neuroblastoma[J]. Przegl Lek, 2004, 61(suppl 2): 3-8.
9
Cashen DV, Parisien RC, Raskin K, et al. Survival data for patients with malignant schwannoma[J]. Clin Orthop Relat Res, 2004, 426: 69-73.
10
张效公,主编. 胸外科主治医师[M]. 北京:协和医科大学出版社,1998, 371-372.
11
孟龙. 巨大纵隔肿瘤的手术技巧[J]. 山东医药,2000, 42(2): 57-58.
12
张国强,蒋耀光,王如文. 巨大纵隔肿瘤的外科治疗[J]. 肿瘤,2004, 24(4): 402-403.
13
张哲明,陈龙,林金祥,等. 巨大纵隔肿瘤的外科治疗[J]. 中国胸心血管外科杂志,2002, 9(4): 307-308.
14
Lin SH, Su NY, Hseu SS, et al. Anesthetic managements of the patients with giant mediastinal tumors-a report of two cases[J]. Acta Anaesthsiol Sin, 1999, 37(3): 133-139.
15
Spring CL, Elserb B. Reexpansion pulmonary edema[J]. Chest, 1983, 84(6): 788.
16
Meyer J, Theilmeier G, Van Aken H, et al. Inhaled prostaglandin E1 for treatment of acute lung injury in severe multiple organ failure[J]. Anesth Analg, 1998, 86(4):753-758.
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