切换至 "中华医学电子期刊资源库"

中华肺部疾病杂志(电子版) ›› 2017, Vol. 10 ›› Issue (04) : 395 -397. doi: 10.3877/cma.j.issn.1674-6902.2017.04.003

所属专题: 文献

论著

肺癌切除术后乳糜胸的早期诊断和治疗
薛志强1,(), 温佳新1, 刘毅1, 任志鹏1, 王彬1, 张成伟1, 刘阳1, 初向阳1   
  1. 1. 100853 北京,中国人民解放军总医院胸外科
  • 收稿日期:2017-05-24 出版日期:2017-08-20
  • 通信作者: 薛志强
  • 基金资助:
    国家自然科学基金资助项目(81573026)

Early diagnosis and treatment of postoperative chylothorax after lung carcinoma surgery

Zhiqiang Xue1,(), Jiaxin Wen1, Yi Liu1, Zhipeng Ren1, Bin Wang1, Chengwei Zhang1, Yang Liu1, Xiangyang Chu1   

  1. 1. Department of Thoracic Surgery, Chinese PLA General Hospital, Beijing 100853, China
  • Received:2017-05-24 Published:2017-08-20
  • Corresponding author: Zhiqiang Xue
  • About author:
    Corresponding author: Xue Zhiqiang, Email:
引用本文:

薛志强, 温佳新, 刘毅, 任志鹏, 王彬, 张成伟, 刘阳, 初向阳. 肺癌切除术后乳糜胸的早期诊断和治疗[J]. 中华肺部疾病杂志(电子版), 2017, 10(04): 395-397.

Zhiqiang Xue, Jiaxin Wen, Yi Liu, Zhipeng Ren, Bin Wang, Chengwei Zhang, Yang Liu, Xiangyang Chu. Early diagnosis and treatment of postoperative chylothorax after lung carcinoma surgery[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2017, 10(04): 395-397.

目的

探讨肺癌切除术后乳糜胸的早期诊断和治疗。

方法

回顾性分析2009年1月至2013年12月我院胸外科肺癌切除术后并发乳糜胸患者的临床病理资料,并比较常规开胸与胸腔镜手术后乳糜胸的差别。

结果

3 479例肺癌切除患者术后并发乳糜胸12例(0.34%,12/3 479),胸腔镜手术组的发生率为0.41%(7/1 719),开胸手术组为0.28%(5/1 760),两者之间未见统计学显著性差异(P>0.05)。11例(91.7%)采用保守治疗,1例(8.3%)再次手术行胸导管结扎后,全部恢复顺利。胸腔镜手术组乳糜胸患者的手术时间(207±29.1)min、平均出血量(142.9±60.7)ml、清扫淋巴结数(20.1±5.7)枚、带胸管时间(13.9±4.9)d、住院时间(26.7±5.7)d,与开胸手术组乳糜胸患者的手术时间(192±72.2)min、平均出血量(220.0±109.5)ml、清扫淋巴结数(14.4±4.5)枚、带胸管时间(13.2±7.8)d、住院时间(27.0±8.7)d相比,未见统计学有显著性差异(P>0.05)。

结论

乳靡胸是肺癌术后的一种少见并发症,与手术方式无关,多数可采用保守措施治愈。

Objective

To explore the early diagnosis and treatment of postoperative chylothorax after lung carcinoma surgery.

Methods

The clinical data of patients with postoperative chylothorax after lung cancer surgery from January 2009 to December 2013 were retrospectively analyzed, the difference between the video-assisted thoracoscopy surgery (VATS) and thoracotomy was compared.

Results

Twelve patients with postoperative chylothorax were identified among 3 479 patients who underwent lung carcinoma surgery (0.34%, 12/3 479). Proportion of postoperative chylothorax was 0.41% in VATS group (7/1 719) and 0.28% in thoracotomy group (5/1 760), the difference was not significant (P>0.05). 11 patients with postoperative chylothorax received conservative therapy, and 1 patient underwent thoracic duct ligation, all patients recovered smoothly. Comparing the VATS with the thoracotomy groups, the mean operative time was 207±29.1 min vs. 192±72.2 min, with no significant difference (P>0.05); and the average blood loss was 142.9±60.7 ml vs. 220.0±109.5 ml, with no significant difference (P>0.05). Comparing the two groups of patients data, the number of lymph node dissection: 20.1±5.7 in VATS group and 14.4±4.5 in the thoracotomy group on average, with no significant difference (P>0.05); postoperative drainage time: 13.9±4.9 days in the VATS group and 13.2±7.8 days in the thoracotomy group on average, with no significant difference (P>0.05); hospital stay: 26.7±5.7 days in the VATS group and 27.0±8.7 days in the thoracotomy group on average, with no significant difference (P>0.05).

Conclusions

Postoperative chylothorax is a rare complication of lung carcinoma resection. The incidence of postoperative chylothorax is not related with operation type. The prognosis is good of chylothorax by early diagnosis and effective conservative treatment.

表1 腔镜手术组乳糜胸与开胸手术组乳糜胸的比较(±s)
1
Johnstone DW. Postoperative chylothorax[J]. Chest Surg Clin N Am, 2002, 12(3): 597-603.
2
Uchida S, Suzuki K, Hattori A, et al. Surgical intervention strategy for postoperative chylothorax after lung resection[J]. Surg Today, 2016, 46(2): 197-202.
3
段晋,施云飞,雷又鸣,等. 肺癌术后乳糜胸诊治分析[J]. 中外医疗,2017, 36(2): 57-59.
4
何锋,林铿强,柯敏,等. 肺癌根治术并发乳糜胸的原因分析及预防[J]. 吉林医学,2016, 37(1): 40-44.
5
Sekine Y. Surgical management of chylothorax after pulmonary resection[J]. Kyobu Geka, 2013, 66 (8 suppl): 741-744.
6
Wang W, Yin W, Shao W, et al. Comparative study of systematic thoracoscopic lymphadenectomy and conventional thoracotomy in resectable non-small cell lung cancer[J]. J Thoracic Dis, 2014, 6(1): 45-51.
7
万黎,王建军,赵峰,等. 肺癌术后乳糜胸17例诊疗体会[J]. 中国肺癌杂志,2009, 12(8): 905-906.
8
Cho HJ, Kim DK, Lee GD, et al. Chylothorax complicating pulmonary resection for lung cancer: effective management and pleurodesis[J]. Ann Thorac Surg, 2014, 97(2): 408-413.
9
郑成义,王朝阳,张伟,等. 18例肺癌术后乳糜胸的临床分析[J]. 《世界最新医学信息文摘:连续型电子期刊》,2015, 15(63): 150-151.
10
Liu CY, Hsu PK, Huang CS, et al. Chylothorax complicating video-assisted thoracoscopic surgery for non-small cell lung cancer[J]. World Surg, 2014, 38(11): 2875-2881.
11
张小文,杨劼,刘文国,等. 胸腔镜下胸导管结扎术的应用解剖[J]. 中国临床解剖性杂志,2014, 32(3): 264-268.
12
Akin H, Olcmen A, Isqorucu O, et al. Approach to patients with chylothorax complicating pulmonary resection[J]. Thorac Cardiovasc Surg, 2012, 60(2): 135-139.
13
Kanzaki M, Sasano S, Murasugi, et al. Early endoscopic treatment of chylothorax develops after surgical treatment of lung cancer patients[J]. Jpn J Thorac Cardiovasc Surg, 2003, 51(10): 506-510.
14
高林春,蒋力. 单孔与三孔胸腔镜肺叶切除术疗效对比[J/CD]. 中华肺部疾病杂志(电子版), 2016, 9(6): 653-654.
15
童燕翔,洪志鹏. 微创外科在肺癌综合治疗中的进展[J/CD]. 中华肺部疾病杂志(电子版), 2013, 6(1): 73-75.
[1] 李辉, 吴奇, 张子琦, 张晗, 王仿, 许鹏. 日间全膝关节置换术早期疗效及标准化流程探索[J]. 中华关节外科杂志(电子版), 2023, 17(06): 889-892.
[2] 陈严城, 忻慰, 李世傲, 钱嘉天, 钱齐荣, 牛大伟, 赵天磊, 符培亮. 髋膝关节置换日间手术和住院手术的倾向性匹配研究[J]. 中华关节外科杂志(电子版), 2023, 17(04): 462-469.
[3] 张银银, 李颖, 李启活, 郭海威, 田瀚, 钟业霖. 髋腰综合征诊断与手术治疗的研究进展[J]. 中华关节外科杂志(电子版), 2023, 17(04): 549-553.
[4] 王玲燕, 邹磊, 洪亮, 宋三兵, 付润, 熊胜男, 宋晓春. 心脏外科术后患者并发低三碘甲状腺原氨酸综合征的影响因素分析[J]. 中华危重症医学杂志(电子版), 2023, 16(05): 399-402.
[5] 黄来明, 张旭东. 雾化吸入布地奈德混悬液联合气管导管涂抹达克罗宁胶浆对改善妇科腹腔镜手术气管插管全身麻醉患者咽喉部不适作用[J]. 中华妇幼临床医学杂志(电子版), 2023, 19(04): 480-486.
[6] 刘林峰, 王增涛, 王云鹏, 钟硕, 郝丽文, 仇申强, 陈超. 足底内侧皮瓣联合甲骨皮瓣在手指V度缺损再造中的临床应用[J]. 中华损伤与修复杂志(电子版), 2023, 18(06): 480-484.
[7] 张浩, 张万福, 韩飞, 佟琳, 王运帷, 李少辉, 陈阳, 曹鹏, 官浩. 游离组织瓣治疗无吻合血管或需困难吻合血管创面的临床进展[J]. 中华损伤与修复杂志(电子版), 2023, 18(05): 442-446.
[8] 梁开地, 缑文斌, 莫居容. 肺癌组织中细胞角蛋白18的表达及与预后的相关性[J]. 中华肺部疾病杂志(电子版), 2023, 16(05): 688-690.
[9] 李双喜, 胡宗凯, 赵静, 黄洁. 肝血管瘤治疗指征及治疗策略[J]. 中华肝脏外科手术学电子杂志, 2023, 12(05): 504-510.
[10] 田驹, 孙伯洋, 杨荣华, 赵向前. 术中意外发现肝外胆管绒毛管状腺瘤的外科处理经验:附两例报道并文献复习[J]. 中华肝脏外科手术学电子杂志, 2023, 12(05): 567-571.
[11] 张天献, 吕云福, 郑进方. 胆总管结石微创治疗进展[J]. 中华肝脏外科手术学电子杂志, 2023, 12(05): 585-588.
[12] 吴周宇, 周宝勇, 李明. 基于PSM分析腹腔镜肝门部胆管癌根治术安全性[J]. 中华肝脏外科手术学电子杂志, 2023, 12(04): 384-388.
[13] 廖承煜, 江斌华, 黄龙, 王丹凤, 田毅峰, 陈实. 腹腔镜下肝左叶肝内胆管细胞癌根治术优化三步法的应用价值[J]. 中华肝脏外科手术学电子杂志, 2023, 12(04): 395-400.
[14] 李晓东, 魏云. 冠状切口额下入路治疗前颅窝巨大脑膜瘤[J]. 中华神经创伤外科电子杂志, 2023, 09(05): 318-319.
[15] 程相阵. 腹茧症9例诊治分析并文献复习[J]. 中华临床医师杂志(电子版), 2023, 17(9): 968-971.
阅读次数
全文


摘要