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中华肺部疾病杂志(电子版) ›› 2017, Vol. 10 ›› Issue (05) : 604 -607. doi: 10.3877/cma.j.issn.1674-6902.2017.05.029

所属专题: 文献

综述

脑钠肽、低氧诱导因子-1α、心肌型脂肪酸结合蛋白在高原肺动脉高压中的研究进展
张欢1, 华毛1, 冯喜英1,(), 马维秀1, 李玉红1   
  1. 1. 810001 西宁,青海大学附属医院呼吸内科
  • 收稿日期:2017-09-13 出版日期:2017-10-20
  • 通信作者: 冯喜英

Research progress of BNP, HIF-1α, H-FABP in high altitude pulmonary hypertension

Huan Zhang1, Mao Hua1, Xiying Feng1()   

  • Received:2017-09-13 Published:2017-10-20
  • Corresponding author: Xiying Feng
引用本文:

张欢, 华毛, 冯喜英, 马维秀, 李玉红. 脑钠肽、低氧诱导因子-1α、心肌型脂肪酸结合蛋白在高原肺动脉高压中的研究进展[J]. 中华肺部疾病杂志(电子版), 2017, 10(05): 604-607.

Huan Zhang, Mao Hua, Xiying Feng. Research progress of BNP, HIF-1α, H-FABP in high altitude pulmonary hypertension[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2017, 10(05): 604-607.

1
国际高原医学会慢性高原病专家小组. 慢性高原病青海诊断标准[J]. 青海医学院学报,2005, 26(1): 3-5.
2
高莹,崔大山,周维新,等. 41例闭塞性肺动脉高压患者应用多普勒超声心动图法与右心导管法测定肺动脉压力的比较[J]. 中国循环杂志,2004, 19(3): 216-218.
3
Maggiorini M, Leon-Velarde F. High-altitude pulmonary hyperten-sion: A pathophysiological entity to different diseases[J]. Eur Respir J, 2003, 22(6): 1019-1025.
4
Humbert M, Sithon O, Simonneau G. Treatment of pulmonary arterial hypertension[J]. N Engl J Med, 2008, 351(14): 1425-1436.
5
Weidemann A, Klanke B, Wagner M, et al. Hypoxia, via stabilization of the hypoxia-inducible factor HIF-1 alpha, is a direct and sufficient stimulus for brain-type natriuretic peptide induction[J]. Biochem J, 2008, 409(1): 233-242.
6
Carrillo-Jimenez R, Borzak S, Hennekens CH. Brain natriuretic peptide:clinical and research challenges[J]. J Cardiovasc Pharmacol Ther, 2007, 12(2): 85- 88.
7
Del Greco MF, Pattaro C, Luchner A, et al. Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster[J]. Hum Mol Genet, 2011, 20(8): 1660-1671.
8
Newton-Cheh C, Larson MG, Vasan RS, et al. Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure[J]. Nat Genet, 2009, 41(3): 348-353.
9
Lajer M, Tarnow L, Jorsal A, et al. Polymorphisms in the B-type natriuretic peptide (BNP) gene are associated with NT-proBNP levels but not with diabetic nephropathy or mortality in type 1 diabetic patients[J]. Nephrol Dial Transplant, 2007, 22(11): 3235-3239.
10
Felker GM, Petersen JW, Mark DB. Natriuretic peptides in the diagnosis and management of heart failure[J]. CMAJ, 2006, 175(6): 611-617.
11
Mauro A, Buscemi M, Provenzano S, et al. Human umbilical cord expresses several vasoactive peptides involved in the local regulation of vascular tone: protein andgene expression of Orphanin, Oxytocin, ANP, eNOS and iNOS[J]. Folia Histochem Cytobiol, 2011, 49(2): 211-218.
12
Szabo G, Rigo J Jr, Nagy B. Physiology and clinical role of natriuretic peptides[J]. Orv Hetil, 2011, 152(26): 1025-1034.
13
Casals G, Ros J, Sionis A, et al. Hypoxia induces B-type natriuretic peptide release in cell lines derived from human cardiomyocytes[J]. Am J Physiol Heart Circ Physiol, 2009, 297(2): H550-H551.
14
Takatsuki S, Wagner BD, Ivy DD. B-type natriuretic peptide and amino-terminal pro-B-type natriuretic peptide in pediatric patients with pulmonary arterial hypertension[J]. Congenit Heart Dis, 2012, 7(3): 259-267.
15
Freeman ML, Landolfo C, Safford RE, et al. Noninvasive assessment of right heart function and hemodynamics during exercise in patients with pulmonary arterial hypertension[J]. South Med J, 2013, 106(2): 141-146.
16
Badesch DB, Champion HC, Sanchez MA, et al. Diagnosis and assess ment of pulmonary arterial hypertension[J]. J Am Coll Cardiol, 2009, 54(1 Suppl): 55-66.
17
Ge RL, Mo VY, Januzzi JL, et al. B-type natriuretic peptide, vascular endothelial growth factor, endothelin-1,and nitric oxide synthase in chronic mountain sickness[J]. Am J Physiol Heart Circ Physiol, 2011, 300(4): 1427-1433.
18
Goto K, Arai M, Watanabe A, et al. Utility of echocardiography versus BNP level for the prediction of pulmonary arterial pressure in patients with pulmonary arterial hypertension[J]. Int Heart J, 2010, 51(5): 343-347.
19
Dentali F, Donadini M, Gianni M, et al. Brain natriuretic peptide as a preclinical marker of chronic pulmonary hypertension in patients withpulmonary embolism[J]. Intern Emerg Med, 2009, 4(2): 123-128.
20
Goto K, Arai M, Watanabe A, et al. Utility of echocardiography versus BNP level for the prediction of pulmonary arterial pressure in pa-tients with pulmonary arterial hypertension[J]. Int Heart J, 2010, 51(5): 343-347.
21
Fomin VV, Popova EN, Kuznetsova AV, et al. Endothelin-1and brain natriuretic peptide in the development of pulmonary hypertension in interstitial lung diseases[J]. Ter Arkh, 2009, 81(12): 58-63.
22
Weitzenblum E, Chaouat A, Canuet M, et al. Pulmonary hypertention in chronic obstructive pulmonary disease and interstitial lung disease[J]. Semin Respir Crit Care Med, 2009, 30(4): 458-470.
23
黄锂新,吴星恒. 心脉隆对窒息新生鼠心肌缺氧诱导因子-1α的影响[J]. 中国当代儿科杂志,2009, 11(8): 683-686.
24
杨月霞,黄文新. HIF-1在缺血缺氧性疾病中的研究进展[J]. 山东医药,2010, 50(20): 111-114.
25
Adams JM, Difazio LT, Rolandelli RH, et al. HIF-1: a key mediator in hypoxia[J]. Acta Physiol Hung, 2009, 96(1): 19-28.
26
刘丽愉. 低氧诱导因子信号通路的研究新进展[J]. 国际病理科学与临床杂志,2011, 31(3): 218-222.
27
周星. 缺氧诱导因子-1α与转化生长因子-β1在早产儿脐血管上的表达及相关研究[D]. 河北医科大学,2010: 28.
28
迟相林,李振光,郭兆荣,等. 缺氧诱导因子-1与缺血缺氧性心脑血管病[J]. 中华老年心脑血管病杂志,2008, 10(6): 471-473.
29
Brahimi-Horn MC, Pouysségur J. Harnessing the hypoxia-inducible factor in cancer and ischemic disease[J]. Biochem Pharmacol, 2007, 73(3): 450-457.
30
蔡拓,周艳芳,邓宇斌. 缺氧诱导因子-1在缺血性脑损伤中的作用[J]. 国际脑血管病杂志,2010, 18 (4): 300-305.
31
Chan SY, Loscalzo J. MicrRNA-210: a unique and pleiotropic hypoxamir[J]. Cell Cycle, 2010, 9(6): 1072-1083.
32
Kulshreshtha R, Davuluri RV, Calin GA, et al. A microRNA component of the hypoxic response[J]. Cell Death Differ, 2008, 15(4): 667-671.
33
Chan YC, Banerjee J, Choi SY, et al. miR-210: the master hypoxamir[J]. Microcirculation, 2012, 19(3): 215-223.
34
Taguchi A, Yanagisaw K, Tanaka M, et al. Identification of hypoxia-inducible factor-lalpha as a novel target for miR-17-92 microRNA cluster[J]. Cancer Res, 2008, 68(14): 5540-5545.
35
Lei Z, Li B, Yang Z, et al. Regulation of HIF-lalpha and VEGF by miR-20btunes tumor cells to adapt to the alteration of oxygen concentration[J]. PLoS One, 2009, 4(10): e7629.
36
Bruning U, Cerone L, Neufeld Z, et al. MicroRNA-155promotes resolution of hypoxia-inducible factor lalpha activity during prolonged hypoxia[J]. Mol Cell Biol, 2011, 31(19): 4087-4096.
37
Crosby ME, Kulshreshtha R, Ivaan M, et al. MicroRNA regulation of DNA repair gene expression in hypoxic stress[J]. Cancer Res, 2009, 69(3): 1221-1229.
38
薛守斌. 缺氧诱导因子-1与缺氧性肺动脉高压的研究进展[J]. 医学综述,2013, 19(19): 3474-3477.
39
李炽观,戴爱国,严鹏科. 低氧诱导因子1在低氧致肺动脉平滑肌细胞增殖中的作用[J]. 中国病理生理杂志,2007, 23(7): 1301-1305.
40
侯巍,杨述红,王欣. 心肌型脂肪酸结合蛋白测定的临床应用[J]. 中国实验诊断学,2003, 7(1): 33-35.
41
Colli An, Josa M, Pomar JL, et al. Heart fatty acid binding protein in the diagnosis of myocardial infarction:where do we stand today?[J].Cardiology, 2007, 108(1): 4-10.
42
Samanta A, Das DK, Jones R, et al. Free radical scavenging by myocardial fatty acid binding protein[J]. Free Radic Res Commun, 1989, 7(2): 73-82.
43
McCann CJ, Glover BM, Menown IB, et al. Novel biomarkers in early diagnosis of acute myocardial infarction compare with cardiac troponin T[J]. Eur Heart J, 2008, 29(230): 2843-2850.
45
衣志勇,蒋知新,李小鹰,等. 心肌型脂肪酸结合蛋白在急性心肌梗死早期诊断中的应用[J]. 中华老年医学杂志,2004, 23(3): 160-163.
46
张欢,华毛,郭月辉. BNP、HIF-2α与高原肺动脉高压关系的研究进展[J/CD]. 中华肺部疾病杂志(电子版), 2016, 9(2): 210-211.
47
李瑞,华毛,冯喜英,等. 心钠素与高原肺动脉高压的相关性研究进展[J/CD]. 中华肺部疾病杂志(电子版), 2015, 8(2): 254-255.
48
贺连芳,华毛. 血清C反应蛋及白细胞介素6与高原肺动脉高压的相关性[J/CD]. 中华肺部疾病杂志(电子版), 2016, 9(2): 215-218.
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