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中华肺部疾病杂志(电子版)

中华肺部疾病杂志(电子版) ›› 2019, Vol. 12 ›› Issue (04) : 416 -419. doi: 10.3877/cma.j.issn.1674-6902.2019.04.003

论著

基于光纤精准分析呼吸气体的临床应用
袁侨英1, 喻金龙1, 周琪1, 石霞1, 陈丽君2(), 熊玮3,†()   
  1. 1. 400038　重庆，陆军军医大学（第三军医大学）西南医院营养科
    3. 400038　重庆，陆军军医大学（第三军医大学）西南医院老年科
  • 收稿日期:2019-04-13 出版日期:2019-08-20
  • 通信作者: 陈丽君, 熊玮
  • 基金资助:
    国家自然科学基金面上项目(81271657); 重庆市社会民生科技创新专项科技创新专项(cstc2016shmszx130067)

Clinical study of accurate analysis of respiratory gas based on optical fiber

Qiaoying Yuan1, Jinlong Yu1, Qi Zhou1, xia Shi1, Wei Xiong2,†()   

  1. 1. Department of Nutrition, Southwest Hospital, Army Military Medical University, Chongqing 400038, China
    2. Department of Geriatrics, Southwest Hospital, Army Military Medical University, Chongqing 400038, China
  • Received:2019-04-13 Published:2019-08-20
  • Corresponding author: Wei Xiong
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袁侨英, 喻金龙, 周琪, 石霞, 陈丽君, 熊玮. 基于光纤精准分析呼吸气体的临床应用[J]. 中华肺部疾病杂志(电子版), 2019, 12(04): 416-419.

Qiaoying Yuan, Jinlong Yu, Qi Zhou, xia Shi, Wei Xiong. Clinical study of accurate analysis of respiratory gas based on optical fiber[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2019, 12(04): 416-419.

目的

基于涡轮传感器及氧传感器测定呼吸机使用患者的呼吸代谢指标，探讨不同性别患者的呼吸代谢变化特征和影响因素。

方法

基于COSMED代谢车的气体分析器测定122例不同性别患者呼吸代谢，其中A组男84例，B组女38例；分析不同性别患者的吸入氧量、呼出二氧化碳量、氧通气当量、最大摄氧量，平均吸入、呼出氧气量、潮气量、肺泡通气量，平均吸入、呼出二氧化碳量、呼吸商、呼吸频率等指标的差别，分析BMI值对呼吸代谢值的影响。

结果

A、B两组间平均O2分压(O2exp)比较有统计学差异：分别为(161±38)vs.(142±29)和118±53)vs.(86±39)，男性患者明显高于女性患者(P<0.05)。2组间CO2产量无统计学差异(P>0.05)。氧通气当量(VE/VO2) (47.56±17.45)vs.(28.98±12.12)2组间有统计学差异。二氧化碳通气当量VE/VCO2、呼吸商R、每公斤摄氧量、平均呼出CO2量2组间比较均无统计学差别(P>0.05)。平均呼出O2量(33.98±10.71)vs.(29.26±11.12)2组间比较有差别(P<0.05)，潮气量VT(0.30±0.09) vs. (0.34±0.09)、摄氧量VO2(142±30)vs.(161±38)两组间有差别，男性患者均高于女性患者(P<0.05)。分钟通气量、平均CO2分压、CO2产量两组间比较均无差别(P>0.05)。

结论

基于传感器测定不同性别人群的呼吸代谢精确、安全，可以辅助分析呼吸代谢状况、评估肺功能，可针对性的满足临床重症患者的诊治需求。

关键词: 呼吸, 代谢, 肺功能, 传感器
Objective

To investigate the characteristics and the influencing factors of respiratory metabolic changes in the patients with different sexes based on the measurement of respiratory metabolic indexes by turbine sensor and oxygen sensor.

Methods

The respiratory metabolism of 122 patients of different sexes (84 males and 38 females) was measured by COSMED metabolic vehicle gas analyzer. The respiratory quotient and respiratory frequency were analyzed, too. The effects of body mass index (BMI) on respiratory metabolic value were also analyzed.

Results

There were significant differences in VO2 and the average partial pressure of O2 between the two groups, and they were significantly higher in male patients than in female ones (P<0.05). There was no significant difference in CO2 production between the two groups (P>0.05). The oxygen ventilation equivalent (VE/VO2) was significantly different between the two groups. There was no significant difference in the ventilation equivalent VE/VCO2, the respiratory quotient R, the oxygen uptake per kilogram and the average exhaled CO2 between the two groups (P>0.05). There were significant differences between the two groups in the average exhaled oxygen volume and the tidal volume and the oxygen uptake VO2, which was higher in male patients than in female ones (P<0.05). There was no difference in the minute ventilation volume and the average partial pressure of CO2 and the CO2 output between the two groups (P>0.05).

Conclusion

The sensor-based measurement of respiratory metabolism in different sex groups is accurate and safe. It can comprehensively understand the respiratory metabolism and assist the evaluation of the cardiopulmonary function of severe patients.

Key words: Respiration, Metabolism, Pulmonary function, Sensor
图1 2组患者摄氧量及平均O2分压比较，*P<0.05
图2 2组间氧通气当量、二氧化碳通气当量比较，*P<0.05
图3 2组间平均呼出O2量比较，*P<0.05
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