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中华肺部疾病杂志(电子版) ›› 2021, Vol. 14 ›› Issue (03) : 325 -328. doi: 10.3877/cma.j.issn.1674-6902.2021.03.015

临床研究

AECOPD患者细菌和病毒感染类型及其与复发风险的相关性
于晓钧1, 孙欣2,()   
  1. 1. 543002 广西梧州市红十字会医院急诊科
    2. 543002 广西梧州市红十字会医院护理部
  • 收稿日期:2021-02-19 出版日期:2021-06-25
  • 通信作者: 孙欣

Correlation between Types of bacterial and viral infections and recurrence risk in patients with AECOPD

Xiaojun Yu1, Xin Sun2()   

  • Received:2021-02-19 Published:2021-06-25
  • Corresponding author: Xin Sun
引用本文:

于晓钧, 孙欣. AECOPD患者细菌和病毒感染类型及其与复发风险的相关性[J]. 中华肺部疾病杂志(电子版), 2021, 14(03): 325-328.

Xiaojun Yu, Xin Sun. Correlation between Types of bacterial and viral infections and recurrence risk in patients with AECOPD[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2021, 14(03): 325-328.

目的

探讨慢性阻塞性肺疾病急性加重(AECOPD)患者细菌和病毒感染类型及其与复发风险的相关性。

方法

选择2018年8月至2019年9月于我院就诊的72例AECOPD患者为对象,所有受试者入院后均接受常规AECOPD治疗及细菌、病毒感染类型检测。治疗出院后随访1年,根据患者是否复发分为复发组和未复发组,并采用Cox回归分析AECOPD患者细菌、病毒感染类型与复发风险的相关性。

结果

72例AECOPD患者中有40.27(29/72)存在病毒感染,43.06%(31/72)的患者细菌感染。铜绿假单胞菌是最常见细菌感染类型25.81%(8/31),其次是鲍曼不动杆菌和肺炎克雷伯菌22.58%(7/31);人鼻病毒是最常见的病毒感染类型48.28%(14/29)和间质肺病毒37.93%(11/29)。随访1年后72例AECOPD患者共失访8例,最终纳入64例AECOPD患者,其中39例患者出现复发为复发组,未复发的25例患者为未复发组。单因素分析显示两组患者卡他莫拉菌、肺炎链球菌、流感嗜血杆菌、甲型流感病毒、人间质肺病毒、人鼻病毒感染比例组间比较差异有统计学意义(P<0.05)。

结论

铜绿假单胞菌、人鼻病毒是AECOPD患者最常见细菌和病毒感染类型,且人鼻病毒、肺炎链球菌、流感嗜血杆菌是AECOPD患者复发的风险因素。

表1 两组患者一般资料及细菌、病毒感染类型比较[n(%)]
表2 AECOPD患者复发的风险因子分析
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