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中华肺部疾病杂志(电子版) ›› 2021, Vol. 14 ›› Issue (04) : 453 -455. doi: 10.3877/cma.j.issn.1674-6902.2021.04.011

临床研究

血清颗粒蛋白前体、C反应蛋白在儿童支原体肺炎中检测的临床意义
刘利梅1, 徐卫华1, 饶晓红1   
  1. 1. 233000 合肥,安徽省儿童医院
  • 收稿日期:2021-03-11 出版日期:2021-08-25
  • 基金资助:
    安徽省重点研究和开发计划项目(1804h08020285)

Clinical significance of serum granuloprotein precursors and C­reactive protein in detection of mycoplasma pneumonia in children

Limei Liu1, Weihua Xu1, Xiaohong Rao1   

  • Received:2021-03-11 Published:2021-08-25
引用本文:

刘利梅, 徐卫华, 饶晓红. 血清颗粒蛋白前体、C反应蛋白在儿童支原体肺炎中检测的临床意义[J]. 中华肺部疾病杂志(电子版), 2021, 14(04): 453-455.

Limei Liu, Weihua Xu, Xiaohong Rao. Clinical significance of serum granuloprotein precursors and C­reactive protein in detection of mycoplasma pneumonia in children[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2021, 14(04): 453-455.

目的

探讨血清颗粒蛋白前体(PGRN)、C反应蛋白(CRP)在儿童支原体肺炎中检测的临床意义。

方法

选取2016年6月至2019年6月我院收治的49例支原体肺炎患儿为观察组,47例细菌性肺炎为对照组。比较两组儿童血清PGRN、CRP水平及临床特征,采用Logistic回归分析判定影响儿童支原体肺炎发生的因素。

结果

观察组与对照组患儿血清PGRN、CRP水平均高于健康组(P<0.05),且观察组患儿血清PGRN、CRP水平均低于对照组患儿(P<0.05);观察组患儿反复呼吸道感染构成比与对照组患儿比较,差异均有统计学意义(P<0.05);Logistic多因素回归分析显示血清PGRN、CRP均是影响支气管肺炎发生的独立危险因素(P<0.05)。

结论

观察患儿血清PGRN、CRP水平均异常升高,且均低于对照组患儿,血清PGRN、CRP在儿童观察发生发展中具有意义。

表1 比较两组儿童血清PGRN、CRP水平
表2 两组患者患儿临床资料
表3 Logistic多因素分析
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