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中华肺部疾病杂志(电子版) ›› 2022, Vol. 15 ›› Issue (04) : 597 -599. doi: 10.3877/cma.j.issn.1674-6902.2022.04.042

病例报告

克罗恩病合并肺结节一例报告并文献复习
陈丽莉1, 高天明1, 王文晶1, 冯旰珠1,()   
  1. 1. 210011 南京,南京医科大学第二附属医院呼吸与危重症医学科
  • 收稿日期:2022-03-17 出版日期:2022-08-25
  • 通信作者: 冯旰珠

A case report of Crohn′s disease combined with pulmonary nodules and a literature review

Lili Chen1, Tianming Gao1, Wenjing Wang1   

  • Received:2022-03-17 Published:2022-08-25
引用本文:

陈丽莉, 高天明, 王文晶, 冯旰珠. 克罗恩病合并肺结节一例报告并文献复习[J/OL]. 中华肺部疾病杂志(电子版), 2022, 15(04): 597-599.

Lili Chen, Tianming Gao, Wenjing Wang. A case report of Crohn′s disease combined with pulmonary nodules and a literature review[J/OL]. Chinese Journal of Lung Diseases(Electronic Edition), 2022, 15(04): 597-599.

克罗恩病(CD)是一种原因不明的反复发作、消化道慢性炎症性肉芽肿性疾病,主要累及小肠,21%~47%的患者伴随肠外表现(EIM),某些EIM可能与CD活动平行[1,2,3]。EIM几乎可以涉及任何器官系统,临床表现多种多样[4]。常见的有巩膜炎、葡萄膜炎、结节性红斑、原发性硬化性胆管炎、坏疽性脓皮病、强直性脊柱炎和胰腺炎等。肠外的肺部表现在CD发病率仅为0.4%[5]。CD相关的肺部病变发病率低,起病隐匿、症状无明显特异性,临床工作中容易被忽略。CD中肺实质受累的几种形式已被认可,包括间质性肺病,如闭塞性细支气管炎伴机化性肺炎(BOOP)、未明确的间质性肺病、非干酪性肉芽肿性炎症和纤维化、实质结节和肉芽肿,肺泡炎和肺泡实变[6,7]。本文报道CD合并肺结节一例,报告及文献复习。

图2 气管镜TBLB病理图
图4 治疗后2021年6月复查胸部CT
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