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中华肺部疾病杂志(电子版) ›› 2023, Vol. 16 ›› Issue (02) : 257 -259. doi: 10.3877/cma.j.issn.1674-6902.2023.02.029

短篇论著

HSP90α在老年恶性胸腔积液中的诊断意义
康慧方1, 孙莉2, 田应选2, 尚文丽2, 刘凌华2, 霍树芬2,()   
  1. 1. 716000 延安,延安大学医学院;710068 西安,陕西省人民医院呼吸与危重症二科
    2. 710068 西安,陕西省人民医院呼吸与危重症二科
  • 收稿日期:2022-12-07 出版日期:2023-04-25
  • 通信作者: 霍树芬
  • 基金资助:
    科技部主动健康和老龄化科技应对国家重点研发计划课题(SQ2018YFC200066,2018YFC2002100,2018YFC2002103); 陕西省人民医院拔尖人才支持计划项目(2021BJ-22)

HSP90α diagnostic significance in the malignant pleural effusion in elderly

Huifang Kang1, Li Sun2, Yingxuan Tian2   

  • Received:2022-12-07 Published:2023-04-25
引用本文:

康慧方, 孙莉, 田应选, 尚文丽, 刘凌华, 霍树芬. HSP90α在老年恶性胸腔积液中的诊断意义[J]. 中华肺部疾病杂志(电子版), 2023, 16(02): 257-259.

Huifang Kang, Li Sun, Yingxuan Tian. HSP90α diagnostic significance in the malignant pleural effusion in elderly[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2023, 16(02): 257-259.

恶性胸腔积液(malignant pleural effusion, MPE)是恶性肿瘤引起的胸腔积液,原发于胸膜的恶性肿瘤或其他部位恶性肿瘤转移至胸膜引起,最常见于肺癌,其次乳腺癌和淋巴瘤,中位生存期3~12个月[1,2]。诊断胸腔积液良恶性的主要方法有胸腔积液脱落细胞学和组织病理学检查,细胞学检查敏感度相对较低。胸腔镜是一项较为安全的检查方法,一些老年患者基础疾病多,免疫功能减退,对胸腔镜等有创检查耐受性差,微创侵入性较低的诊断方法具有临床意义[3,4,5]。热休克蛋白(HSP90α)是一种新的全癌诊断生物标记物,在多种癌症中高表达[6]。本文对我院收治的67例胸腔积液患者HSP90α和传统肿瘤标志物表达水平进行分析,报道如下。

表1 两组实验室指标比较
表2 两组胸腔积液指标水平
表3 胸腔积液单项及联合检测的诊断价值
1
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