| 1 |
Rhee C，Dantes R，Epstein L，et al.Using objective clinical data to track progress on preventing and treating sepsis：CDC's new‘Adult Sepsis Event’surveillance strategy［J］.BMJ Qual Saf，2019，28（4）：1-9.
|
| 2 |
Wafaisade A，Lefering R，Bouillon B，et al.Epidemiology and risk factors of sepsis after multiple trauma：an analysis of 29 829 patients from the Trauma Registry of the German Society for Trauma Surgery［J］.Crit Care Med，2011，39（4）：621-628.
|
| 3 |
Mas-Celis F，Olea-Lopez J，Parroquin-Maldonado Ja.Sepsis in trauma：a deadly complication［J］.Arch Med Res，2021，52（8）：1-12.
|
| 4 |
Dodek P.ACP Journal Club.Review：Tight glucose control reduces septicemia，but not death，and increases hypoglycemia in critically ill adults［J］.Ann Intern Med，2009，150（2）：JC1-5.
|
| 5 |
姜 东，冉龙艳，雷传江，等.脓毒症的前世今生及序贯器官衰竭认知及理念［J/CD］.中华肺部疾病杂志（电子版），2023，16（5）：605-610.
|
| 6 |
Koch C，Edinger F，Fischer T，et al.Comparison of qSOFA score，SOFA score，and SIRS criteria for the prediction of infection and mortality among surgical intermediate and intensive care patients［J］.World J Emerg Surg，2020，15（1）：63.
|
| 7 |
冯 珂，勾 燚，吕博辉，等.创伤后脓毒症早期预警诊断血浆生物标志物的研究进展［J］.中国急救复苏与灾害医学杂志，2024，19（6）：830-834.
|
| 8 |
Bedard AF，Mata LV，Dymond C，et al.A scoping review of worldwide studies evaluating the effects of prehospital time on trauma outcomes［J］.Int J Emerg Med，2020，13（1）：1-15.
|
| 9 |
Reinhart K，Daniels R，Kissoon N，et al.Recognizing sepsis as a global health priority-A WHO resolution［J］.N Engl J Med，2017，377（5）：414-417.
|
| 10 |
Engel C，Brunkhorst FM，Bone HG，et al.Epidemiology of sepsis in Germany：results from a national prospective multicenter study［J］.Intensive Care Med，2007，33（4）：606-618.
|
| 11 |
Chung S，Choi D，Cho J，et al.Timing and associated factors for sepsis-3 in severe trauma patients：a 3-year single trauma center experience［J］.Acute Crit Care，2018，33（3）：1-9.
|
| 12 |
Osborn TM，Tracy JK，Dunne JR，et al.Epidemiology of sepsis in patients with traumatic injury［J］.Crit Care Med，2004，32（11）：2234-2240.
|
| 13 |
Park J，Choi Y.Exosome identification for personalized diagnosis and therapy［J］.Biomed Eng Lett，2014，4（3）：258-268.
|
| 14 |
Martin GS，Mannino DM，Eaton SB，et al.The epidemiology of sepsis in the united states from 1979 through 2000［J］.N Engl J Med，2003，348（16）：1546-1554.
|
| 15 |
Lakomkin N，Sathiyakumar V，Wick B，et al.Incidence and predictive risk factors of postoperative sepsis in orthopedic trauma patients［J］.J Orthop Traumatol，2017，18（2）：1-9.
|
| 16 |
Lu HX，Du J，Wen DL，et al.Development and validation of a novel predictive score for sepsis risk among trauma patients［J］.World J Emerg Surg，2019，14（1）：1-10.
|
| 17 |
Guo F，Shen H.Glycosylated hemoglobin as a predictor of sepsis and all-cause mortality in trauma patients［J］.Infect Drug Resist，2021，14：2517-2526.
|
| 18 |
Angus DC，Linde-Zwirble WT，Lidicker J，et al.Epidemiology of severe sepsis in the United States：Analysis of incidence，outcome，and associated costs of care［J］.Crit Care Med，2001，29（7）：1303-1310.
|
| 19 |
Giustozzi M，Ehrlinder H，Bongiovanni D，et al.Coagulopathy and sepsis：Pathophysiology，clinical manifestations and treatment［J］.Blood Rev，2021，50：100864.
|
| 20 |
Qian M，Zhu B，Zhan Y，et al.Analysis of negative results of metagenomics next-generation sequencing in clinical practice［J］.Front Cell Infect Microbiol，2022，12：892076.
|
| 21 |
Bai GQ，Dong L，Li A，et al.A comparative study on the identification methods of Acinetobacter baumannii colonization and infection［J］.Clin Exp Med，2013，12（21）：4.
|
| 22 |
甘志新，胡雍军，肖 晶，等.降钙素原在脓毒血症与肺部感染中的研究进展［J/CD］.中华肺部疾病杂志（电子版），2024，17（4）：663-666.
|
| 23 |
Yadav P，Trehanpati N，Maiwall R，et al.Soluble factors and suppressive monocytes can predict early development of sepsis in acute-on-chronic liver failure［J］.Hepatol Commun，2022，6（8）：2105-2120.
|
| 24 |
Lei R，Arain H，Obaid M，et al.Ultra-sensitive and semi-quantitative vertical flow assay for the rapid detection of interleukin-6 in inflammatory diseases［J］.Biosensors（Basel），2022，12（9）：756.
|
| 25 |
Qi W，Liu J，Yu T，et al.Ae1/Sbe1 maize-derived high amylose improves gut barrier function and ameliorates type Ⅱdiabetes in high-fat diet-fed mice by increasing Akkermansia［J］.Front Nutr，2022，9：999020.
|
| 26 |
Romejko K，Markowska M，Niemczyk S.The review of current knowledge on neutrophil gelatinase-associated lipocalin（NGAL）［J］.Int J Mol Sci，2023，24（13）：10470-10470.
|
| 27 |
van Engelen TS，Wiersinga WJ，Scicluna BP，et al.Biomarkers in sepsis［J］.Crit Care Clin，2018，34（1）：139-152.
|
| 28 |
McHugh L，Seldon TA，Brandon RA，et al.A molecular host response assay to discriminate between sepsis and infection-negative systemic inflammation in critically ill patients：discovery and validation in independent cohorts［J］.PLoS Med，2015，12（12）：e1001916.
|
| 29 |
Sweeney TE，Shidham A，Wong HR，et al.A comprehensive timecourse-based multicohort analysis of sepsis and sterile inflammation reveals a robust diagnostic gene set［J］.Sci Transl Med，2015，7（287）：1-10.
|
| 30 |
Pan W，Zhang AQ，Gu WJ，et al.Identification of haplotype tag single nucleotide polymorphisms within the nuclear factor-κB family genes and their clinical relevance in patients with major trauma［J］.Crit Care，2015，19（1）：1-10.
|
| 31 |
Zhang H，Lu Y，Sun G，et al.The common promoter polymorphism rs11666254 downregulates FPR2/ALX expression and increases risk of sepsis in patients with severe trauma［J］.Crit Care，2017，21（1）：1-10.
|
| 32 |
International Study of the Epidemiology of paediatric trauma：papsa research study［J］.World J Surg，2018，42（3）：1-12.
|
| 33 |
Chadda KR，Puthucheary Z.Persistent inflammation，immunosuppression，and catabolism syndrome（PICS）：a review of definitions，potential therapies，and research priorities［J］.Br J Anaesth，2024，132（3）：507-518.
|
| 34 |
Dobson GP，Morris JL，Letson HL.Immune dysfunction following severe trauma：A systems failure from the central nervous system to mitochondria［J］.Front Med，2022，9：1-15.
|
| 35 |
Liu X，Zhang Z，Ruan J，et al.Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores［J］.Nature，2016，535（7610）：153-158.
|
| 36 |
Lu H，Wen D，Sun J，et al.Enhancer polymorphism rs10865710 associated with traumatic sepsis is a regulator of PPARG gene expression［J］.Crit Care，2019，23（1）：430.
|
| 37 |
Rossaint R，Afshari A，Bouillon B，et al.The European guideline on management of major bleeding and coagulopathy following trauma：sixth edition［J］.Crit Care，2023，27（1）：80.
|
| 38 |
Ma Y，Zhou Y，Wu F，et al.The bidirectional interactions between inflammation and coagulation in fracture hematoma［J］.Tissue Eng Part B Rev，2019，25（1）：46-54.
|
| 39 |
Huang M，Cai S，Su J.The Pathogenesis of sepsis and potential therapeutic targets［J］.Int J Mol Sci，2019，20（21）：1-15.
|
| 40 |
Danckwardt S，Hentze MW，Kulozik AE.Pathologies at the nexus of blood coagulation and inflammation：thrombin in hemostasis，cancer，and beyond［J］.J Mol Med（Berl），2013，91（11）：1257-1271.
|
| 41 |
Burggraf M，Polan C，Husen M，et al.Trauma induced clotting factor depletion in severely injured children：a single center observational study［J］.World J Emerg Surg，2020，15（1）：31.
|
| 42 |
Lucas TA，Zhu L，Buckwalter MS.Spleen glia are a transcriptionally unique glial subtype interposed between immune cells and sympathetic axons［J］.Glia，2021，69（7）：1799-1815.
|
| 43 |
Nguyen H，Alawieh A，Bastian D，et al.Targeting the complement alternative pathway permits graft versus leukemia activity while preventing graft versus host disease［J］.Clin Cancer Res，2020，26（13）：3481-3490.
|
| 44 |
Xiong Z，Wang Q，Li W，et al.Platelet-derived growth factor-d activates complement system to propagate macrophage polarization and neovascularization［J］.Front Cell Dev Biol，2021，9：686886.
|
| 45 |
Ward PA.The harmful role of C5a on innate immunity in sepsis［J］.J Innate Immun，2010，2（5）：439-445.
|
| 46 |
Shang W，Cao Y，Li Y，et al.Effect of early hemostasis strategy on secondary post-traumatic sepsis in trauma hemorrhagic patients［J］.Injury，2024，55（2）：111205.
|
| 47 |
Brohi K，Gruen RL，Holcomb JB.Why are bleeding trauma patients still dying？ ［J］.Intensive Care Med，2019，45（5）：709-711.
|
| 48 |
Dobson GP，Morris JL，Davenport LM，et al.Traumatic-induced coagulopathy as a systems failure：a new window into hemostasis［J］.Semin Thromb Hemost，2020，46（02）：199-214.
|
| 49 |
Thompson KB，Krispinsky LT，Stark RJ.Late immune consequences of combat trauma：a review of trauma-related immune dysfunction and potential therapies［J］.Mil Med Res，2019，6（1）：1-10.
|
| 50 |
Efron PA，Mohr AM，Bïhorac A，et al.Persistent inflammation，immunosuppression，and catabolism and the development of chronic critical illness after surgery［J］.Surgery，2018，164（2）：178-184.
|
| 51 |
Muire PJ，Schwacha MG，Wenke JC.Systemic T cell exhaustion dynamics is linked to early high mobility group box protein 1（HMGB1）driven hyper-inflammation in a polytrauma rat model［J］.Cells，2021，10（7）：1-16.
|
| 52 |
Yang Y，Ye Y，Chen C，et al.Acute traumatic brain injury induces CD4+and CD8+T Cell functional impairment by upregulating the expression of PD-1 via the activated sympathetic nervous system［J］.Neuroimmunomodulation，2019，26（1）：43-57.
|
| 53 |
Kimura F，Shimizu H，Yoshidome H，et al.Immunosuppression following surgical and traumatic injury［J］.Surgery Today，2010，40（9）：793-808.
|
| 54 |
Gabrilovich DI，Nagaraj S.Myeloid-derived suppressor cells as regulators of the immune system［J］.Nat Rev Immunol，2009，9（3）：162-174.
|
| 55 |
Schmidt KFR，Gensichen JS，Schroevers M，et al.Trajectories of post-traumatic stress in sepsis survivors two years after ICU discharge：a secondary analysis of a randomized controlled trial［J］.Crit Care，2024，28（1）：35.
|
| 56 |
Wang Z，Zhang W，Chen L，et al.Lymphopenia in sepsis：a narrative review［J］.Crit Care，2024，28（1）：315.
|
| 57 |
周 然，尹万红，杨 吕，等.急性呼吸循环障碍的改良七步法分析及治疗流程［J］.中华内科杂志，2023，62（12）：1423-1429.
|
| 58 |
Li D，Zhang X，Lu Y，et al.Post-sepsis psychiatric disorder：Pathophysiology，prevention，and treatment［J］.Neurol Sci，2024，45（7）：3093-3105.
|