Analysis of 64-slice spiral CT imaging features of solitary pulmonary nodules in patients with lung cancer

doi:10.3877/cma.j.issn.1674-6902.2021.01.009

Abstract

Abstract:

Objective

To study the diagnostic value of 64-slice spiral CT in solitary pulmonary nodules (SPN) of lung cancer.

Methods

From May 2015 to May 2019, 158 lung cancer patients with SPN confirmed by pathology were enrolled in our hospital. According to different pathological types of lung cancer, they were divided into group A (adenocarcinoma, 112 cases), group B (squamous cell carcinoma, 34 cases), and group C (small cell carcinoma, 12 cases). All patients underwent 64-slice spiral CT scanning. The changes of CT values of three groups of SPN plain scanning and enhancement sequences (enhancement 30, 60, 90, 120, 180, 300, 600 s) were compared, and the enhancement methods, enhancement net value and enhancement rate of the three groups were analyzed, and the relative clearance values and clearance rates of each delayed scanning point (180, 300, 600s) after the emergence of dynamic enhancement peak of SPN were compared.

Results

With the prolongation of scanning time, the SPN CT values of the three groups increased first and then decreased significantly, and peaked at 60-180 s. The SPN CT value of group A was significantly higher than that of group B and C (P<0.05), and the SPN CT value of group A and B was significantly lower than that of group C (P<0.05); The value of SPN CT in group C was significantly lower than that in group A and B (P<0.05). The non-uniform enhancement rates of SPN in group A, B and C were 25.0%, 64.7% and 50.0%, respectively, and the uniform enhancement rates were 75.0%, 35.2% and 50.0%, respectively, among which the difference of SPN enhancement methods in group A and B was statistically significant (P<0.05). Relative clearance value and clearance rate of SPN delayed scanning 180 s after peak dynamic enhancement in group A and B were significantly higher than those in group C (P<0.05); There was no significant difference in the relative clearance value and clearance rate of three groups of SPN delayed scanning for 300 seconds (P>0.05); The relative clearance value and clearance rate of SPN in group B and C were significantly higher than those in group A (P<0.05).

Conclusion

64-slice spiral CT can observe the SPN imaging characteristics of lung cancer patients with different pathological types, which is of great significance in the qualitative diagnosis of SPN.

Key words: 64-slice spiral CT, Bronchogenic carcinoma, Solitary pulmonary nodules

Jinlin Ma, Xiaoyan Ma, Haiqiang Wang. Analysis of 64-slice spiral CT imaging features of solitary pulmonary nodules in patients with lung cancer[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2021, 14(01): 48-52.

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Figures/Tables 4

References 26

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组　别	例数	平扫	增强30 s	增强60 s	增强90 s	增强120 s	增强180 s	增强300 s	增强600 s
A组	112	30.40±5.40	61.50±4.87	68.60±2.45	79.16±4.35	81.45±3.90	77.12±6.05	71.04±3.56	66.07±3.25
B组	34	30.45±5.68	54.56±5.78^a	63.80±5.12^a	73.24±3.75^a	82.30±6.65	78.84±7.89	71.90±4.30	64.87±2.80
C组	12	31.16±3.97	54.40±3.62^a	62.38±5.91^a	71.98±4.87^a	73.05±4.25^ab	66.39±3.28^ab	62.87±2.83^ab	57.86±2.67^ab
F值		0.109	31.759	35.991	35.311	19.421	18.033	29.348	37.732
P值		0.897	0.000	0.000	0.000	0.000	0.000	0.000	0.000

组　别	例数	平扫	增强30 s	增强60 s	增强90 s	增强120 s	增强180 s	增强300 s	增强600 s
A组	112	30.40±5.40	61.50±4.87	68.60±2.45	79.16±4.35	81.45±3.90	77.12±6.05	71.04±3.56	66.07±3.25
B组	34	30.45±5.68	54.56±5.78^a	63.80±5.12^a	73.24±3.75^a	82.30±6.65	78.84±7.89	71.90±4.30	64.87±2.80
C组	12	31.16±3.97	54.40±3.62^a	62.38±5.91^a	71.98±4.87^a	73.05±4.25^ab	66.39±3.28^ab	62.87±2.83^ab	57.86±2.67^ab
F值		0.109	31.759	35.991	35.311	19.421	18.033	29.348	37.732
P值		0.897	0.000	0.000	0.000	0.000	0.000	0.000	0.000

组　别	例数	强化净增值(HU)	强化率(%)
A组	112	53.30±5.24	1.80±0.45
B组	34	51.72±5.41	1.79±0.42
C组	12	45.55±3.68^ab	1.77±0.40
F值		12.463	0.029
P值		0.000	0.972

组　别	例数	强化净增值(HU)	强化率(%)
A组	112	53.30±5.24	1.80±0.45
B组	34	51.72±5.41	1.79±0.42
C组	12	45.55±3.68^ab	1.77±0.40
F值		12.463	0.029
P值		0.000	0.972

组　别	例数	相对廓清值(HU)			廓清率(%)
组　别	例数	延迟扫描180 s	延迟扫描300 s	延迟扫描600 s	延迟扫描180 s	延迟扫描300 s	延迟扫描600 s
A组	112	5.30±3.94	11.82±2.20	14.20±2.05	6.20±3.24	14.16±2.41	17.15±2.46
B组	34	5.10±3.78	11.90±4.50	19.95±6.52^a	6.12±3.46	14.06±3.38	23.48±6.53^a
C组	12	10.57±3.15^ab	12.10±3.53	20.16±4.10^a	13.68±4.14^ab	15.18±4.07	25.17±5.42^a
F值		10.579	0.053	41.467	27.638	0.794	49.049
P值		0.000	0.948	0.000	0.000	0.454	0.000

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