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中华肺部疾病杂志(电子版) ›› 2021, Vol. 14 ›› Issue (03) : 341 -343. doi: 10.3877/cma.j.issn.1674-6902.2021.03.020

临床研究

Th17/Treg水平对脑卒中并发肺部感染的临床分析
孙文博1,(), 连汝静1   
  1. 1. 024000 赤峰,赤峰学院附属医院
  • 收稿日期:2021-02-15 出版日期:2021-06-25
  • 通信作者: 孙文博

linical analysis of Th17 /Treg level in patients with cerebral apoplexy complicated with pulmonary infection

Wenbo Sun1(), Rujing Lian1   

  • Received:2021-02-15 Published:2021-06-25
  • Corresponding author: Wenbo Sun
引用本文:

孙文博, 连汝静. Th17/Treg水平对脑卒中并发肺部感染的临床分析[J/OL]. 中华肺部疾病杂志(电子版), 2021, 14(03): 341-343.

Wenbo Sun, Rujing Lian. linical analysis of Th17 /Treg level in patients with cerebral apoplexy complicated with pulmonary infection[J/OL]. Chinese Journal of Lung Diseases(Electronic Edition), 2021, 14(03): 341-343.

目的

探讨Th17/Treg水平对脑卒中并发肺部感染的临床特征。

方法

回顾性分析2018年10月至2020年10月我院收治的86例脑卒中患者,分析脑卒中患者并发肺部感染情况,对比脑卒中并发肺部感染和未并发感染患者临床资料,采用Logistic回归分析影响脑卒中并发肺部感染的因素。

结果

脑卒中患者肺部感染发生率为17.44%;脑卒中肺部感染患者卒中类型、外周血Th17、Treg、Th17/Treg与肺部未感染患者比较,差异有统计学意义(P<0.05);Logistic多因素回归分析显示Th17/Treg、Treg、侵入性操作、出血性脑卒中均是影响脑卒中并发肺部感染的独立危险因素(OR=2.790,2.214,2.266,1.754);Th17、Treg、Th17/Treg预测脑卒中并发肺部感染的最佳截断点分别为5.21%、2.20%、2.03,灵敏度分别为69.23%、80.77%、84.62%,特异度分别为84.31%、77.45%、79.41%,AUC分别为0.819、0.834、0.844。

结论

脑卒中并发肺部感染患者外周血Th17/Treg平衡向Th17偏移,且Th17/Treg、Treg、侵入性操作、出血性脑卒中均是影响脑卒中并发肺部感染的危险因素,Th17、Treg、Th17/Treg均可作为预测脑卒中并发肺部感染的临床意义。

表1 脑卒中并发肺部感染和未并发感染患者临床资料
表2 肺部感染相关因素的Logistic分析
表3 Th17/Treg预测脑卒中并发肺部感染(%)
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