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中华肺部疾病杂志(电子版) ›› 2021, Vol. 14 ›› Issue (03) : 338 -340. doi: 10.3877/cma.j.issn.1674-6902.2021.03.019

临床研究

NLR、PLR、hs-CRP预测ICU重症肺炎死亡风险
罗冰燕1, 刘伟洪1, 张晓亮1, 陈惠峰1   
  1. 1. 516211 惠州,广东省惠州市第六人民医院
  • 收稿日期:2020-12-19 出版日期:2021-06-25

Prediction of the risk of death in patients with severe pneumonia in ICUby NLR, PLR, hs-CRP

Bingyan Luo1, Weihong Liu1, Xiaoliang Zhang1   

  • Received:2020-12-19 Published:2021-06-25
引用本文:

罗冰燕, 刘伟洪, 张晓亮, 陈惠峰. NLR、PLR、hs-CRP预测ICU重症肺炎死亡风险[J]. 中华肺部疾病杂志(电子版), 2021, 14(03): 338-340.

Bingyan Luo, Weihong Liu, Xiaoliang Zhang. Prediction of the risk of death in patients with severe pneumonia in ICUby NLR, PLR, hs-CRP[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2021, 14(03): 338-340.

目的

探讨血清中性粒细胞与淋巴细胞比值(NLR)、血小板与淋巴细胞比值(PLR)、超敏C反应蛋白(hs-CRP)联合检测对重症监护病房(ICU)重症肺炎28 d死亡风险预测价值。

方法

选择2018年2月至2020年10月我院收治的116例入住ICU重症肺炎患者,统计28 d死亡情况,分为死亡组和存活组,对比临床资料。Logistic多因素回归分析影响ICU重症肺炎死亡的因素。制作受试者工作特征曲线(ROC),分析联合检测血清NLR、PLR、hs-CRP对ICU重症肺炎28 d死亡的预测价值。

结果

ICU重症肺炎患者28 d病死率为30.17%(35/116)。死亡组患者入住ICU时间、机械通气占比、急性生理学与慢性健康状况评分系统Ⅱ(APACHEⅡ)评分、肺炎严重程度(PSI)评分、C反应蛋白、白细胞计数(WBC)、血清NLR、PLR及hs-CRP水平均显著高于存活组(P<0.05)。Logistic回归分析结果显示,PSI评分、血清NLR、PLR及hs-CRP均为影响ICU重症肺炎患者死亡的因素(OR=3.827、4.354、3.327、2.765,P<0.05)。

结论

血清NLR、PLR、hs-CRP三者联合对ICU重症肺炎患者28 d死亡的预测效能较高,可作为评ICU重症肺炎患者28 d预后死亡的参考指标。

表1 死亡组和存活组患者临床资料对比(±s)
表2 影响ICU重症肺炎死亡的多因素分析Logistic回归分析
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