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中华肺部疾病杂志(电子版) ›› 2023, Vol. 16 ›› Issue (01) : 125 -127. doi: 10.3877/cma.j.issn.1674-6902.2023.01.035

综述

液体活检技术在肺癌中的应用进展
褚依然1, 岳麓1,()   
  1. 1. 266071 青岛,南京医科大学附属青岛临床医学院·青岛市市立医院肿瘤科
  • 收稿日期:2022-06-25 出版日期:2023-02-25
  • 通信作者: 岳麓

Progress in the application of liquid biopsy technique in lung cancer

Yiran Chu1, Lu Yue1()   

  • Received:2022-06-25 Published:2023-02-25
  • Corresponding author: Lu Yue
引用本文:

褚依然, 岳麓. 液体活检技术在肺癌中的应用进展[J]. 中华肺部疾病杂志(电子版), 2023, 16(01): 125-127.

Yiran Chu, Lu Yue. Progress in the application of liquid biopsy technique in lung cancer[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2023, 16(01): 125-127.

液体活检作为体外诊断的一个分支,包括游离循环肿瘤细胞(circulating tumor cells, CTCs)检测、循环肿瘤DNA(circulating tumor, DNA)检测、外泌体及循环RNA(circulating RNA, circRNA)检测。目前,液体活检在多个领域,如肿瘤筛查、肿瘤分期分级、预后评估、精准用药及肿瘤个体化治疗、耐药监控、肿瘤复发与转移中广泛应用。肺癌是我国发病率和病死率最高的癌症。随着生物技术的进步与发展,液体活检技术在肺癌的早期诊断、预后评估、疗效检测中展现出巨大临床应用价值,肺癌液体活检技术可以贯穿肺癌全病程诊疗,包括早期筛查、检测、个体化用药指导、预后评估等。本文将对不同液体活检技术在肺癌中的应用进展作一综述。

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