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中华肺部疾病杂志(电子版) ›› 2025, Vol. 18 ›› Issue (06) : 991 -995. doi: 10.3877/cma.j.issn.1674-6902.2025.06.023

论著

慢性病资源利用在老年慢性阻塞性肺疾病患者病情感知与呼吸困难恐惧中的中介效应研究
缪绸, 刘洁(), 张位位   
  1. 210003 南京,南京市胸科医院呼吸内科
  • 收稿日期:2025-10-08 出版日期:2025-12-25
  • 通信作者: 刘洁

Study on the mediating effect of chronic disease resource utilization in disease perception and fear of dyspnea in elderly COPD patients

Chou Miao, Jie Liu(), Weiwei Zhang   

  1. Department of Respiratory Medicine, Nanjing Chest Hospital, Nanjing 210003, China
  • Received:2025-10-08 Published:2025-12-25
  • Corresponding author: Jie Liu
引用本文:

缪绸, 刘洁, 张位位. 慢性病资源利用在老年慢性阻塞性肺疾病患者病情感知与呼吸困难恐惧中的中介效应研究[J/OL]. 中华肺部疾病杂志(电子版), 2025, 18(06): 991-995.

Chou Miao, Jie Liu, Weiwei Zhang. Study on the mediating effect of chronic disease resource utilization in disease perception and fear of dyspnea in elderly COPD patients[J/OL]. Chinese Journal of Lung Diseases(Electronic Edition), 2025, 18(06): 991-995.

目的

分析老年慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)患者慢性病资源利用、疾病感知与呼吸困难恐惧水平的关系。

方法

纳入2020年1月至2025年4月我院收治的219例COPD患者,采用临床资料调查表、慢性病资源利用问卷(chronic disease resource utilization questionnaire, CIRS)、简易疾病感知问卷(simple disease perception questionnaire, BIPQ)及呼吸困难信念问卷(breathlessness beliefs questionnaire, BBQ)中的恐惧呼吸困难维度进行调查。Pearson相关性分析三者相关性,使用SPSS宏程序Model-4分析慢性病资源利用的中介作用是否成立,并进行Bootstrap检验。

结果

219例患者中呼吸困难恐惧评分(14.23±4.67)分,CIRS评分(49.74±6.41)分,BIPQ评分(50.32±8.56)分。CIRS评分与BIPQ评分(r=-0.337)、呼吸困难恐惧评分(r=-0.256)负相关,BIPQ评分与呼吸困难恐惧评分(r=0.257)正相关(P<0.05)。中介效应结果显示,疾病感知对呼吸困难恐惧的直接效应为0.105,慢性病资源利用在疾病感知与呼吸困难恐惧中的中介效应为0.035,占总效应的25.00%。

结论

老年COPD患者呼吸困难恐惧水平总体处于高位,慢性病资源利用在疾病感知与呼吸困难恐惧水平具有中介效应。

Objective

To analyze the relationship between chronic disease resource utilization, disease perception and respiratory muscle group exercise compliance in elderly patients with chronic obstructive pulmonary disease (COPD).

Methods

A total of 219 COPD patients who were treated in our hospital from January 2020 to April 2025 were included in the study. The general information questionnaire, the chronic disease resource utilization questionnaire (CIRS), the simple disease perception questionnaire (BIPQ), and the breathlessness beliefs questionnaire(BBQ) were used for the investigation.Pearson correlation analysis of the three correlation, using SPSS macro program Model-4 to analyze whether the intermediary role of chronic disease resource utilization is established, and carry out Bootstrap test.

Results

Among the 219 patients, the dyspnea fear score (14.23±4.67), CIRS score (49.74±6.41) and BIPQ score (50.32±8.56) were scored. CIRS score was negatively correlated with BIPQ score (r=-0.337) and dyspnea fear score (r=-0.256), while BIPQ score was positively correlated with dyspnea fear score (r=0.257) (P<0.05). The results of the mediating effect show that the direct effect of disease perception on the fear of dyspnea is 0.105, and the mediating effect of chronic disease resource utilization between disease perception and the fear of dyspnea is 0.035, accounting for 25.00% of the total effect.

Conclusion

The fear level of dyspnea in elderly COPD patients is generally at a high level, and the utilization of chronic disease resources has a partial mediating effect on disease perception and dyspnea fear level.

表1 COPD患者临床资料及不同特征评分差异
表2 COPD患者不同量表得分情况
表3 Pearson相关性分析
图1 中介模型路径系数图(标准化)
表4 中介效应回归结果
表5 中介效应检验结果
1
罗宸婧,盛芳芳,张静,等. 以全球视角对中国慢性阻塞性肺疾病负担及未来趋势分析[J/OL]. 中华肺部疾病杂志(电子版), 2024, 17(6): 855-860.
2
Sunwoo BY, Raphelson JR, Malhotra A. Chronic obstructive pulmonary disease and obstructive sleep apnea overlap: who to treat and how?[J]. Expert Rev Respir Med, 2024, 18(7): 527-537.
3
Wang W, Wang L, Fan R, et al. Relationship among depressive symptoms, dyspnea-related fear and sarcopenia in patients with chronic obstructive pulmonary disease: The mediating effect of physical activity[J]. Chron Respir Dis, 2025, 22: 14799731251335028.
4
Cai Y, Ren X, Wang J, et al. Effects of breathing exercises in patients with chronic obstructive pulmonary disease: A network meta-analysis[J]. Arch Phys Med Rehabil, 2024, 105(3): 558-570.
5
Cai S, Yao J, Han M, et al. The effect of cognition in combination with an ACBT on dyspnea-related kinesiophobia in patients with moderate to severe COPD: Quasirandomized controlled trial study[J]. Geriatr Nurs, 2024, 56: 138-147.
6
Mooren K, Smit K, Engels Y, et al. "When I am breathless now, I don′t have the fear that′s linked to it" :a case series on the potential of EMDR to break the dyspnea-anxiety cycle in COPD[J]. BMC Pulm Med, 2022, 22(1): 456.
7
李爱群,李利花,王芳,等. 慢性病资源利用在冠心病PCI术后患者自我超越与自我管理行为间的中介效应[J]. 护理学报2024, 31(6): 13-17.
8
Moradi G, Piroozi B, Khayyati F, et al. The effect of COVID-19 on utilization of chronic diseases services[J]. Chronic Illn, 2024, 20(2): 309-319.
9
Huang LM, Tan CY, Chen X, et al. A qualitative study on illness perception and coping behaviors among patients with chronic obstructive pulmonary disease: Implications for intervention[J]. Int J Chron Obstruct Pulmon Dis, 2024, 19: 2467-2479.
10
樊敏娜,蒋颜. 慢性心力衰竭病人资源利用情况影响因素的路径分析[J]. 中国卫生统计2023, 40(5): 754-757.
11
方积乾. 生物医学研究的统计方法[M]. 北京,高等教育出版社,2007.
12
中华医学会呼吸病学分会慢性阻塞性肺疾病学组,中国医师协会呼吸医师分会慢性阻塞性肺疾病工作委员会,陈荣昌,等.慢性阻塞性肺疾病诊治指南(2021年修订版)[J]. 中华结核和呼吸杂志2021, 44(3): 170-205.
13
钟慧琴,范玲,邵亚,等. 中文版慢性病资源调查问卷应用于糖尿病患者的信效度分析[J]. 中国全科医学2014(23): 2779-2782.
14
鲍杨娟,黄丽华,王智乾,等. 心理一致感在COPD患者慢性病资源利用与疾病不确定感间的中介效应[J]. 护理与康复2024, 23(5): 1-6.
15
梅雅琪,李惠萍,杨娅娟,等. 中文版疾病感知问卷简化版在女性乳腺癌患者中的信效度检验[J]. 护理学报2015, 22(24): 11-14.
16
De Peuter S, Janssens T, Van Diest I, et al. Dyspnea-related anxiety: the dutch version of the breathlessness beliefs questionnaire[J]. Chron Respir Dis, 2011, 8(1): 11-19.
17
缪小浪,钮美娥,韩燕霞,等. 慢性阻塞性肺疾病患者呼吸困难恐惧影响因素及路径分析[J]. 护理学杂志2024, 39(18): 37-41.
18
Peng LC, Xu M, Wang Y, et al. Latent profile analysis of dyspnea-related kinesiophobia in older adults with chronic obstructive pulmonary disease[J]. Heart Lung, 2025, 69: 241-247.
19
Li P, Han X, Li J, et al. Aerobic exercise training engages the canonical wnt pathway to improve pulmonary function and inflammation in COPD[J]. BMC Pulm Med, 2024, 24(1): 236.
20
施丽萍,许震娟. 健康赋权在老年COPD病人反刍思维和自我管理的中介作用[J]. 蚌埠医学院学报2024, 49(11): 1539-1545.
21
Liu YR, Wang Y, Liu J, et al. Path analysis of illness perception, medication beliefs, family support on inhaler adherence in elderly COPD patients: Based on triadic reciprocal determinism[J]. Patient Educ Couns, 2025, 130: 108465.
22
Jankovic J, Djurdjevic N, Jandric A, et al. The influence of gender differences on the illness perception and women′s point of view on COPD[J]. Bratisl Lek Listy, 2023, 124(11): 797-801.
23
Tanaka T, Okita M, Jenkins S, et al. Clinical and psychological impact of chronic pain in people with chronic obstructive pulmonary disease[J]. Int J Chron Obstruct Pulmon Dis, 2022, 17: 893-903.
24
周会珍,王国文. 赋能和积极度在老年COPD患者慢性病资源和自我管理间的链式中介作用[J]. 中华现代护理杂志2025, 31(28): 3868-3873.
25
Wang Y, Zou X, Xiong C, et al. Influencing mechanisms of kinesiophobia in middle-aged and elderly patients with chronic obstructive pulmonary disease: a cross-sectional study[J]. BMC Pulm Med, 2025, 25(1): 233.
26
刘佳欣,吴樱,彭丽霞,等. 健康赋权在养老机构老年人创伤后成长和慢性病自我管理的中介作用[J]. 现代预防医学2022, 49(12): 2228-2234, 2261.
27
Jarab AS, Al-Qerem W, Alzoubi KH, et al. Determinants of poor chronic obstructive pulmonary disease control[J]. Libyan J Med, 2025, 20(1): 2507987.
28
陈杨,朱林芳,袁怀红. 维持性血液透析患者健康促进生活方式与慢性病资源利用的研究[J]. 华西医学2023, 38(7): 1027-1033.
29
马洪镇,牛玉柏,宋馥栗. 成年人记忆的情绪效应及情绪偏向[J]. 人类工效学2022, 28(6): 51-56.
30
Phanareth K, Purreskov GT, Nielsen EF, et al. Reduced chronic obstructive pulmonary disease-related utilization of health care services and increased social activities by patients offered a 24/7 accessible telehealth service based on the epital care model: pragmatic modified stepped wedge randomized controlled trial[J]. J Med Internet Res, 2025, 27: e65300.
31
Wang T, Huang YM, Chan HY. Exploration of features of mobile applications for medication adherence in asia: narrative review[J].J Med Internet Res, 2024, 26: e60787.
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