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中华肺部疾病杂志(电子版) ›› 2026, Vol. 19 ›› Issue (03) : 500 -503. doi: 10.3877/cma.j.issn.1674-6902.2026.03.025

综述

慢性阻塞性肺疾病急性加重期并发呼吸衰竭风险预测模型研究进展
柯雨仙, 刘罡, 郭莹莹, 何李谦, 姜轶()   
  1. 610000 成都,成都医学院第一附属医院呼吸与危重症医学科·老年呼吸病四川省高校重点实验室
  • 收稿日期:2026-03-18 出版日期:2026-06-25
  • 通信作者: 姜轶

Research progress on risk prediction models for respiratory failure complicating acute exacerbation of chronic obstructive pulmonary disease

Yuxian Ke, Gang Liu, Yingying Guo   

  • Received:2026-03-18 Published:2026-06-25
引用本文:

柯雨仙, 刘罡, 郭莹莹, 何李谦, 姜轶. 慢性阻塞性肺疾病急性加重期并发呼吸衰竭风险预测模型研究进展[J/OL]. 中华肺部疾病杂志(电子版), 2026, 19(03): 500-503.

Yuxian Ke, Gang Liu, Yingying Guo. Research progress on risk prediction models for respiratory failure complicating acute exacerbation of chronic obstructive pulmonary disease[J/OL]. Chinese Journal of Lung Diseases(Electronic Edition), 2026, 19(03): 500-503.

慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease, AECOPD)是慢性阻塞性肺疾病病程进展中的重要阶段及导致住院、机械通气及死亡风险增加的重要原因。呼吸衰竭(respiratory failure, RF)是AECOPD严重并发症之一,可显著增加机械通气需求、院内死亡风险及医疗资源消耗。早期识别高危患者对优化治疗决策和改善预后具有临床意义。近年来,随着电子病历数据积累及机器学习方法发展,AECOPD并发RF风险预测模型的报道不断增多。研究显示,传统统计学模型和机器学习模型具有一定风险评估价值,部分模型在内部验证中表现出较好的预测效能。相关文献报道存在回顾性设计较多、终点定义不统一、外部验证不足及临床应用转化有限等问题。本文系统梳理AECOPD并发RF风险预测模型的研究现状,总结病理生理基础、模型构建方法及应用进展,探讨未来发展方向。

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