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中华肺部疾病杂志(电子版) ›› 2026, Vol. 19 ›› Issue (03) : 496 -499. doi: 10.3877/cma.j.issn.1674-6902.2026.03.024

综述

喉上神经阻滞治疗咳嗽高敏综合征中的临床应用及研究进展
张雯1, 丁锦屏2, 叶东樊1, 孙晓容1, 徐智1,()   
  1. 1400037 重庆,陆军(第三)军医大学第二附属医院呼吸与危重症医学中心
    2400037 重庆,陆军(第三)军医大学第二附属医院麻醉科
  • 收稿日期:2025-11-04 出版日期:2026-06-25
  • 通信作者: 徐智
  • 基金资助:
    重庆市科卫联合医学科研项目(2024GGXM001); 重庆市公共卫生中青年骨干人才(GWZQN202508); 重庆市自然科学基金面上项目(CSTB2024NSCQ-MSX1114); 陆军军医大学第二附属医院临床研究专项项目(2024F030)

Clinical application and research progress of superior laryngeal nerve block in the treatment of cough hypersensitivity syndrome

Wen Zhang, Jinping Ding, Dongfan Ye   

  • Received:2025-11-04 Published:2026-06-25
引用本文:

张雯, 丁锦屏, 叶东樊, 孙晓容, 徐智. 喉上神经阻滞治疗咳嗽高敏综合征中的临床应用及研究进展[J/OL]. 中华肺部疾病杂志(电子版), 2026, 19(03): 496-499.

Wen Zhang, Jinping Ding, Dongfan Ye. Clinical application and research progress of superior laryngeal nerve block in the treatment of cough hypersensitivity syndrome[J/OL]. Chinese Journal of Lung Diseases(Electronic Edition), 2026, 19(03): 496-499.

咳嗽高敏综合征(cough hypersensitivity syndrome, CHS)是难治性及不明原因慢性咳嗽的核心发病机制,病理生理基础为咳嗽反射弧病理性改变致咳嗽阈值显著降低,使患者对多类轻微刺激产生过度咳嗽反应。目前,传统药物,如神经调节剂常受限于疗效不足或不良反应明显,临床亟需有效干预手段。作为一种微创神经调控技术,喉上神经阻滞术(superior laryngeal nerve block, SLNB)通过精准阻断异常感觉信号的传入,直接干预CHS病理环节,具有治疗优势。本文阐述了SLNB神经生物学基础,明确了其作为介入治疗靶点科学性;介绍了SLNB临床实践,包括操作技术,详细对比了不同手术路径、定位方法及操作要点;疗效评估,系统回顾了该技术近年来临床疗效数据;安全性谱,简述了相关并发症及预防措施。本文评价了SLNB在临床应用中优势与局限性,对未来发展方向进行探讨,为SLNB临床规范化应用及研究提供参考。

表1 喉上神经阻滞三种主要方法比较
1
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