To investigate the allergens categories of adult with asthma and provide scientific basis for its prevention and treatment. To investigate the diagnostic value of serum total immunoglobin E(TIgE) test and eosinophil cationic protein in asthma.

Ninty patients with asthma were detected the reactions to 6 kind of inhalation and 12 kind of ingestion of the mixed-allergen-specific IgE(SIgE) and total immunoglobin E(TIgE) using rapid automated detection system (CAP).

①In 90 asthma patients, allergens total positive rate was 68.89%, the inhaled allergens positive rate was 58.89%, eating allergen positive rate was 38.89%; ②the majority of mixed inhaled allergens are Wx3 (artemisia, plantago, chenopodium genus, solidago, urtica) and Hx2(house dust, dust mites, flour hiding, cockroaches), the majority of mixed food allergens are Fx3 (wheat, oats, corn, sesame, buckwheat), Fx5(protein, milk, cod fish, peanuts, soybeans); ③TIgE positive rate was 64.44%, the majority of patients with asthma were with 1-3 main mixed allergens. Type, ECP levels were correlated with TIgE. Allergen type has no significant correlation with ECP. Serum TIgE in SIgE positive group was significantly higher than SIgE negative group, P<0.01. Compared with SIgE negative group, ECP was no significant difference with SIgE positive group, P>0.05.

Wx3(artemisia, plantago, chenopodiumgenus, solidago, urtica)is the most important mixed allergens of bronchial asthma in Xinjiang. Mixed allergen initial screen the major types of allergens in patients. If screen positive, the individual allergens can be further determined. When the result was negative in common inhalant allergens test, TIgE can be used to suggest the probability of allergies, and help doctors decide whether a group of patients need further examination. ECP can not judge allergies in patients. The results may provide the guideline to specific immunity therapy (desensitization treatment).