To analyze the clinical features and CT imaging findings of 12 patients with influenza A virus (H1N1) pneumoniain before and after treatment from January to March 2019 in Liangshan Second People′s Hospital, Xichang, Sichuan Province, China.

Twelve patients with confirmed as influenza A viral pneumonia admitted to the Department of Respiratory Medicine of Liangshan Second People′s Hospital from January to March 2019 in Liangshan District, Xichang, Sichuan Province, China, were enrolled as the subjects of this study. Their clinical features, laboratory examination indexes and CT imaging results were analyzed before and after treatment.

There was no significant difference in the levels of leukocytes, neutrophils, lymphocytes and platelets before and after treatment (P>0.05). The levels of glutamic oxaloacetic transaminase, total bilirubin expression, direct bilirubin, alkaline phosphatase and lactate dehydrogenase were significantly higher before treatment than those after treatment (P<0.05). As a result, 91.67% of the included patients received treatment for more than 5 days, 91.67% had a fever exceeding 38.5 ℃, 66.67% had headache and myalgia, 91.67% had shortness of breath and cough, 50.00% had cough and white sputum, 66.67% had wheezing & tightness in the chest, 50.00% had purpura, 66.67% had red pharynx, and 75.00% had moist rale in the lungs. CT findings showed pulmonary hilar lesions in 8.33% of the patients, peripheral lesions in 25%, subpleural lesions in 8.33%, and multiple lesions in 58.33%. Among them, the ground-glass shadow accounted for 50.00%, patch-flake shadow accounted for 75.00%, dispersive consolidation shadow and extensive pulmonary fibrosis accounted for 25.00%, diffuse nodular shadow accounted for 16.67%. The patients with the lesions <30% of the total lung area accounted for 16.67%, the patients with the lesions for 30%-50% of the total lung area accounted for 33.33%, and the patients with the lesions >50% of the total lung area accounted for 50.00%.

The main clinical symptoms of the patients with influenza A (H1N1) virus pneumonia are fever, shortness in breath, and mild cough. The white blood cells as the laboratory indicators are normal. The main imaging findings are ground-glass, patch-flake, and dispersive consolidation shadow. Most patients have a good prognosis, and severe patients may have pulmonary fibrosis.