切换至 "中华医学电子期刊资源库"

中华肺部疾病杂志(电子版) ›› 2020, Vol. 13 ›› Issue (02) : 282 -285. doi: 10.3877/cma.j.issn.1674-6902.2020.02.034

综述

系统性硬化病相关肺部疾病的诊治进展
吴晓1, 王庆文1,()   
  1. 1. 518035 深圳,北京大学深圳医院风湿免疫科
  • 收稿日期:2019-11-01 出版日期:2020-04-25
  • 通信作者: 王庆文

Progress in diagnosis and treatment of pulmonary diseases associated with systemic sclerosis

Xiao Wu1, Qingwen Wang1()   

  • Received:2019-11-01 Published:2020-04-25
  • Corresponding author: Qingwen Wang
引用本文:

吴晓, 王庆文. 系统性硬化病相关肺部疾病的诊治进展[J]. 中华肺部疾病杂志(电子版), 2020, 13(02): 282-285.

Xiao Wu, Qingwen Wang. Progress in diagnosis and treatment of pulmonary diseases associated with systemic sclerosis[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2020, 13(02): 282-285.

1
Gabrielli A. Scleroderma[J]. N Engl J Med, 2009, 360(19): 1989-2003.
2
Barnes J, Mayes MD. Epidemiology of systemic sclerosis:incidence, prevalence, survival, riskfactors, malignancy, and environmental triggers[J]. Curr Opin Rheumatol, 2012, 24(2): 165-170.
3
Launay D, Sitbon O, Hachulla E, et al. Survival in systemic sclerosis-associated pulmonary arterial hypertension in the modern management era[J]. Ann Rheum Dis, 2013, 72(12): 1940-1946.
4
Steen VD, Medsger TA. Changes in causes of death in systemic sclerosis, 1972-2002[J]. Ann Rheum Dis, 2007, 66(7): 940.
5
Ranque B, Mouthon L. Geoepidemiology of systemic sclerosis[J]. Autoimmun Rev, 2010, 9(5): A311-A318.
6
Akter T, Silver RM, Bogatkevich GS. Recent advances in understanding the pathogenesis of scleroderma-interstitial lung disease[J]. Curr Rheumatol Rep, 2014, 16(4): 411.
7
Elhai M, Meune C, Boubaya M, et al. Mapping and predicting mortality from systemic sclerosis[J]. Ann Rheum Dis, 2017, 76: 1897-905.
8
Tyndall AJ, Bannert B, Vonk M, et al. Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research(EUSTAR) database[J]. Ann Rheum Dis, 2010, 69(10): 1809.
9
Volkmann ER, Tashkin DP, Sim M, et al. Short-term progression of interstitial lung disease in systemic sclerosis predicts long-term survival in two independent clinical trial cohorts[J]. Ann Rheum Dis, 2019, 78(1): 122-130.
10
Goh NS, Hoyles RK, Denton CP, et al. Short-term pulmonary function trends are predictive of mortality in interstitial lung disease associated with systemic sclerosis[J]. Arthritis Rheumatol, 2017, 69(8): 1670-1678.
11
Goh NS, Desai SR, Veeraraghavan S, et al. Interstitial lung disease in systemic sclerosis: a simple staging system[J]. Am J Respir Crit Care Med, 2008, 177: 1248-1254.
12
Fischer A, Swigris JJ, Groshong SD, et al. Clinically significant interstitial lung disease in limited scleroderma: histopathology, clinical features, and survival[J]. Chest, 2008, 134(3): 601-605.
13
Kim DS, Yoo B, Lee JS, et al. The major histopathologic pattern of pulmonary fibrosis in scleroderma is nonspecific interstitial pneumonia[J]. Sarcoidosis Vasc Diffuse Lung Dis, 2002, 19(2): 121-127.
14
Okamoto M, Fujimoto K, Sadohara J, et al. A retrospective cohort study of outcome in systemic sclerosis-associated interstitial lung disease[J]. Respir Investig, 2016, 54(6): 445-453.
15
Solomon JJ, Olson AL, Fischer A, et al. Scleroderma lung disease[J]. Eur Respir Rev, 2013, 22: 6-19.
16
Tashkin DP, Elashoff R, Clements PJ, et al. Scleroderma Lung Study Research Group. Cyclophosphamide versus placebo in scleroderma lung disease[J]. N Engl J Med, 2006, 354: 2655-2666.
17
Kowal-Bielecka O, Fransen J, Avouac J, et al. Update of EULAR recommendations for the treatment of systemic sclerosis[J]. Ann Rheum Dis, 2017, 76(8): 1327-1339.
18
Tashkin DP, Elashoff R, Clements PJ, et al. Effects of 1-year treatment with cyclophosphamide on outcomes at 2 years in scleroderma lung disease[J]. Am J Respir Crit Care Med, 2007, 176(10): 1026-1034.
19
Tashkin DP, Roth MD, Clements PJ, et al. Sclerodema Lung Study Ⅱ Investigators. Mycophenolate mofetil versus oral cyclophosphamide in scleroderma-related interstitial lung disease (SLS Ⅱ): a randomised controlled, double-blind, parallel group trial[J]. Lancet Respir Med, 2016, 4: 708-719.
20
Dheda K, Lalloo UG, Cassim B, et al. Experience with azathioprine in systemic sclerosis associated with interstitial lung disease[J]. Clin Rheumatol, 2004, 23: 306-309.
21
Nadashkevich O, Davis P, Fritzler M, et al. A randomized unblinded trial of cyclophosphamide versus azathioprine in the treatment of systemic sclerosis[J]. Clin Rheumatol, 2006, 25: 205-212.
22
Jordan S, Distler JH, Maurer B, et al. Effects and safety of rituximab in systemic sclerosis: an analysis from the European Scleroderma Trial and Research (EUSTAR) Group[J]. Ann Rheum Dis, 2015, 74: 1188-1194.
23
Daoussis D, Liossis SN, Tsamandas AC, et al. Experience with rituximab in scleroderma: results from a 1-year, proof-of-principle study[J]. Rheumatology (Oxford, England), 2010, 49: 271-280.
24
Daoussis D, Melissaropoulos K, Sakellaropoulos G, et al. A multicenter,open-label, comparative study of B-cell depletion therapy with rituximab for systemic sclerosis-associated interstitial lung disease[J]. Semin Arthritis Rheum, 2017, 46(5): 625-631.
25
Sari A, Guven D, Armagan B, et al. Rituximab experience in patients with long-standing systemic sclerosis-associated interstitial lung disease: a series of 14 patients[J]. J Clin Rheumatol, 2017, 23(8): 411-415.
26
Miura Y, Saito T, Fujita K, et al. Clinical experience with pirfenidone in five patients with scleroderma-related interstitial lung disease[J]. Sarcoidosis Vasc Diffuse Lung Dis, 2014, 31(3): 235-238.
27
Khanna D, Albera C, Fischer A, et al. An Open-label, Phase Ⅱ Study of the Safety and Tolerability of Pirfenidone in Patients with Scleroderma-associated Interstitial Lung Disease: the LO-TUSS Trial [J]. J Rheumatol, 2016, 43(9): 1672-1679.
28
Bendstrup E, Wuyts W, Alfaro T, et al. Nintedanib in idiopathic pulmonary fibrosis: practical management recommendations for potential adverse events[J]. Respiration, 2019, 97(2): 173-184.
29
Huang J, Beyer C, Palumbo-Zerr K, et al. Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis[J]. Ann Rheum Dis, 2016, 75: 883-890.
30
Huang J, Maier C, Zhang Y, et al. Nintedanib inhibits macrophage activation and ameliorates vascular and fibrotic manifestations in the Fra2 mouse model of systemic sclerosis[J]. Ann Rheum Dis, 2017, 76: 1941-1948.
31
Wollin L, Maillet I, Quesniaux V, et al. Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis[J]. J Pharmacol Exp Ther, 2014, 349: 209-220.
32
Host L, Nikpour M, Calderone A, et al. Autologous stem cell transplantation in systemic sclerosis: a systematic review[J]. Clin Exp Rheumatol, 2017, 106(4): 198-207.
33
Burt RK, Shah SJ, Dill K, et al. Autologous non-myeloablative haemopoietic stem-cell transplantation compared with pulse cyclophosphamide once per month for systemic sclerosis (ASSIST): an open-label, randomised phase 2 trial[J]. Lancet, 2011, 378: 498-506.
34
Van Laar JM, Farge D, Sont JK, et al. EBMT/EULAR Scleroderma Study Group. Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis: a randomized clinical trial[J]. JAMA, 2014, 311: 2490-2498.
35
Miele CH, Schwab K, Saggar R, et al. Lung Transplant Out-comes in Systemic Sclerosis with Significant Esophageal Dys-function. A Comprehensive Single-Center Experience[J]. Ann Am Thorac Soc, 2016, 13(6): 793-802.
36
Garca-Hernandez FJ, Castillo-Palma MJ, Tolosa-Vilella C, et al. Pulmonary hypertension in Spanish patients with systemic sclerosis. Data from the RESCLE registry[J]. Clin Rheumatol, 2019, 38(4): 1117-1124.
37
Niklas K, Niklas A, Mularek-Kubzdela T, et al. Prevalence of pulmonary hypertension in patients with systemic sclerosis and mixed connective tissue disease[J]. Medicine (Baltimore), 2018, 97(28): e11437.
38
Sundaram SM, Chung L. An update on systemic sclerosis-associated pulmonary arterial hypertension: a review of the current literature[J]. Curr Rheumatol Rep, 2018, 20(2): 10.
39
Morrisroe K, Stevens W, Sahhar J, et al. Australian Scleroderma Interest Group (ASIG). Epidemiology and disease characteristics of systemic sclerosis-related pulmonary arterial hypertension: results from a real-life screening programme[J]. Arthritis Res Ther, 2017, 19(1): 42.
40
Ramjug S, Hussain N, Hurdman J, et al. Idiopathic and systemic sclerosis-associated pulmonary arterial hypertension: a comparison of demographic, hemodynamic, and MRI characteristics and outcomes[J]. Chest, 2017, 152(1): 92-102.
41
Coghlan JG, Denton CP, Grunig E, et al. DETECT study group. Evidence-based detection of pulmonary arterial hypertension in systemic sclerosis: the DETECT study[J]. Ann Rheum Dis, 2014, 73: 1340-1349.
42
Taichman DB, Ornelas J, Chung L, et al. Pharmacologic therapy for pulmonary arterial hypertension in adults: Chest guideline and expert panel report[J]. Chest, 2014, 146: 449-475.
43
Galie N, Humbert M, Vachiery JL, et al. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension[J]. Revistaespanola de Cardiologia (English ed.), 2016, 69: 177.
44
McLaughlin VV, Archer SL, Badesch DB, et al. ACCF/AHA. ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association[J]. Circulation, 2009, 119: 2250-2294.
[1] 伏洪玲, 刘瀚旻. 支气管肺发育不良及肺动脉高压有关信号通路研究现状[J]. 中华妇幼临床医学杂志(电子版), 2022, 18(05): 497-505.
[2] 吴丽娜, 魏林, 曾志贵, 张梁, 何恩辉, 檀玉乐, 朱志军, 孙丽莹. 肺动脉高压靶向药物联合肝移植治疗重度门脉性肺动脉高压一例[J]. 中华移植杂志(电子版), 2022, 16(06): 376-378.
[3] 郑珊珊, 郑哲, 黄洁, 廖中凯, 宋云虎, 房晓楠, 刘盛. 主动脉内球囊反搏作为心脏移植桥接治疗对晚期心力衰竭合并肺动脉高压患者的疗效[J]. 中华移植杂志(电子版), 2022, 16(05): 277-284.
[4] 代芬, 卞士柱. 无创机械通气联合肺康复在肺动脉高压呼吸衰竭治疗中的临床应用[J]. 中华肺部疾病杂志(电子版), 2023, 16(04): 560-562.
[5] 李丹阳, 李满祥. 肠道菌群失调在肺动脉高压发病中的研究进展[J]. 中华肺部疾病杂志(电子版), 2023, 16(03): 432-434.
[6] 任成山, 卞士柱, 胡明冬. 肺动脉高压的成因及治疗新理念[J]. 中华肺部疾病杂志(电子版), 2023, 16(01): 1-5.
[7] 张璐, 卞士柱. 肺动脉高压患者药物治疗依从性及健康管理分析[J]. 中华肺部疾病杂志(电子版), 2023, 16(01): 107-109.
[8] 代芬, 卞士柱. Ⅰ期心脏运动康复在肺动脉高压患者中的临床意义[J]. 中华肺部疾病杂志(电子版), 2022, 15(05): 721-723.
[9] 毕先金, 王瑞, 伍鼎建, 张学森. 茶多酚防治肺动脉高压的研究进展[J]. 中华肺部疾病杂志(电子版), 2022, 15(04): 593-596.
[10] 李彩霞, 彭丽娜. 血浆ADMA联合BNP与慢性阻塞性肺疾病并发肺动脉高压的相关性分析[J]. 中华肺部疾病杂志(电子版), 2022, 15(04): 545-547.
[11] 张璐, 卞士柱. 改良后呼吸康复操对肺动脉高压患者生活质量的影响[J]. 中华肺部疾病杂志(电子版), 2022, 15(03): 422-424.
[12] 黄朝旺, 韦雅琴, 许发琼, 徐康乔, 胡巧, 张静, 夏世金, 胡明冬. mmu_circ_0001033过表达慢病毒载体的构建与鉴定[J]. 中华肺部疾病杂志(电子版), 2022, 15(02): 141-145.
[13] 杨益, 黄秋红, 尤再春. 环状RNA在肺动脉高压发病机制中的研究进展[J]. 中华肺部疾病杂志(电子版), 2022, 15(02): 276-278.
[14] 余林阳, 王美英, 李建斌, 楼骁斌, 谢思远, 马志忠, 齐海英, 李稼. 高原地区肺炎合并右心功能衰竭体征患儿的肺动脉压力和心脏形态与功能的特征[J]. 中华临床医师杂志(电子版), 2023, 17(05): 535-544.
[15] 王金志, 陶新曹, 谢万木, 傅志辉, 赵蕴伟, 黄强, 翟振国. 球囊肺动脉成形术在慢性血栓栓塞性肺动脉高压治疗中的进展[J]. 中华介入放射学电子杂志, 2023, 11(03): 262-267.
阅读次数
全文


摘要