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中华肺部疾病杂志(电子版) ›› 2022, Vol. 15 ›› Issue (02) : 230 -233. doi: 10.3877/cma.j.issn.1674-6902.2022.02.023

临床研究

肺癌根治术后患者生活质量纵向变化轨迹及影响因素
刘亨娅1, 刘廷挺2,(), 昌建波3   
  1. 1. 402360 重庆,大足区人民医院手术室
    2. 402360 重庆,大足区人民医院产科
    3. 402360 重庆,大足区人民医院胸心外科
  • 收稿日期:2021-10-02 出版日期:2022-04-25
  • 通信作者: 刘廷挺

Longitudinal changes and influencing factors of quality of life of patients after radical lung cancer surgery

Hengya Liu1, Tingting Liu2(), Jianbo Chang3   

  • Received:2021-10-02 Published:2022-04-25
  • Corresponding author: Tingting Liu
引用本文:

刘亨娅, 刘廷挺, 昌建波. 肺癌根治术后患者生活质量纵向变化轨迹及影响因素[J]. 中华肺部疾病杂志(电子版), 2022, 15(02): 230-233.

Hengya Liu, Tingting Liu, Jianbo Chang. Longitudinal changes and influencing factors of quality of life of patients after radical lung cancer surgery[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2022, 15(02): 230-233.

目的

分析肺癌根治术后患者生活质量纵向变化轨迹及其影响因素。

方法

选择2018年1月至2021年2月我院进行手术的67例肺癌患者为对象,采用欧洲癌症研究和治疗协作组生活质量核心问卷(QLQ-C30)评分评估术后1个月、3个月、6个月生活质量,并采用重复方差测量分析评估术后6个月内生活质量动态变化情况,同时收集社会人口学资料和临床特征资料,采用多元线性回归模型筛选术后6个月内生活质量动态变化的影响因素。

结果

术后6个月,除认知功能外,所有患者生理、社会、角色、情绪及整体生活质量评分均提升(P<0.05);术后1个月,吸烟情况和手术范围为生活质量的影响因素(相关系数R=0.485,决定系数R2=0.114);术后第3个月,辅助治疗、抑郁为生活质量的影响因素(相关系数R=0.376,决定系数R2=0.141);术后第6个月,辅助治疗为生活质量的影响因素(R=0.461,决定系数R2=0.212)。

结论

肺癌患者根治术后生活质量呈现动态变化趋势,吸烟、手术范围、辅助治疗、抑郁显著影响,根据术后不同时期肺癌患者生活质量特点及影响因素,采取个性化干预措施,可提高患者生活质量。

表1 患者临床资料情况(n=67)
表2 患者生活质量和SDS评分情况(±s)
表3 患者术后生活质量影响因素回归分析
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