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中华肺部疾病杂志(电子版) ›› 2020, Vol. 13 ›› Issue (02) : 179 -182. doi: 10.3877/cma.j.issn.1674-6902.2020.02.011

论著

生命体征及综合评分在预测热射病患者预后中的价值分析
张庭秀1, 王琴2, 施光清2, 马李杰2,(), 李福祥2, 肖贞良2   
  1. 1. 610083 成都,成都市第二人民医院呼吸与危重症医学一科
    2. 610083 成都,西部战区总医院呼吸与危重症医学科
  • 收稿日期:2019-07-03 出版日期:2020-04-25
  • 通信作者: 马李杰
  • 基金资助:
    国家自然科学基金青年项目(81800088); 四川省卫生和计划生育委员会科研课题(18PJ020)

Value analysis on vital signs and comprehensive scores in predicting prognosis of patients with thermoplegia

Tingxiu Zhang1, Qin Wang2, Guangqing Shi2, Lijie Ma2,(), Fuxiang Li2, Zhenliang Xiao2   

  1. 1. Department of Respiratory Diseases, The Chengdu Second Peoples′s Hospital, Chengdu 610083, China
    2. Department of Respiratory Medicine, General Hospital of Western Theater Command, Chengdu 610083, China
  • Received:2019-07-03 Published:2020-04-25
  • Corresponding author: Lijie Ma
引用本文:

张庭秀, 王琴, 施光清, 马李杰, 李福祥, 肖贞良. 生命体征及综合评分在预测热射病患者预后中的价值分析[J]. 中华肺部疾病杂志(电子版), 2020, 13(02): 179-182.

Tingxiu Zhang, Qin Wang, Guangqing Shi, Lijie Ma, Fuxiang Li, Zhenliang Xiao. Value analysis on vital signs and comprehensive scores in predicting prognosis of patients with thermoplegia[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2020, 13(02): 179-182.

目的

探讨热射病患者入院时生命体征及综合评分在预测临床预后中的价值。

方法

收集西部战区总医院2012年1月至2018年12月收治入院的34例热射病患者临床资料,根据预后情况分为存活组与死亡组,回顾性分析两组患者临床资料,评价患者入院时生命体征及综合评分在判断该病预后中的临床价值。

结果

34例患者中,29例患者好转出院,5例患者死亡,死亡率为14.71%(5/34),死亡组及存活组中多器官功能障碍综合征(MODS)发生率依次为100%及55.17%(16/29);死亡组患者平均年龄、入院时呼吸频率、心率及APACHE Ⅱ评分均高于存活组(P<0.05),GCS评分低于存活组(P=0.014);死亡组患者总住院时间及ICU时间长于存活组(P<0.05),且呼吸衰竭和酸碱平衡紊乱发生率及呼吸机使用率均高于存活组(P< 0.05),但两组患者入院时体温及平均动脉压差异无统计学意义(P>0.05)。此外,入院时心率、APACHE Ⅱ评分及GCS评分在预测热射病患者死亡中的ROC曲线下面积均大于0.9,入院时呼吸频率、体温及平均动脉压在ROC曲线下面积依次为0.735、0.797及0.614。

结论

热射病患者入院时心率、APACHEⅡ评分及GCS评分在预测临床预后中具有较高诊断价值,呼吸频率、体温在预测临床预后中具有中等诊断价值。

Objective

To assess the values of vital signs and comprehensive scores in predicting the prognosis of the patients with thermoplegia.

Methods

The clinical data of 34 patients who were hospitalized and diagnosed as thermoplegia in our hospital from January 2012 to December 2018 were retrospectively studied. The patients were divided into a survival group and a death group according to their prognosis, and the clinical data of the two groups were analyzed to assess the value of each index in predicting the prognosis of thermoplegia.

Results

Among the 34 patients, 29 were discharged after improvement and 5 died, with the mortality rate of 14.71% (5/34). Furthermore, the incidence of multiple organ dysfunction syndrome (MODS) in the death group was 100%, while it was 55.17% (16/29) in the survival group. The average age and the respiratory rate, heart rate and APACHE Ⅱ score on admission in the death group were higher than those of the survival group (P<0.05). However, the GCS score of the death group was lower than that of the survival group (P=0.014). Moreover, the total length of stay in the hospital and in the ICU of the death group was longer than that of the survival group (P<0.05). However, the average body temperature and the arterial pressure of the two groups had no statistical significant difference (P>0.05). More importantly, the areas under the ROC curves of the heart rate, APACHE Ⅱ score and GCS score were greater than 0.9 in predicting the death of the patients with thermoplegia, while the areas under the ROC curves of the respiratory rate, temperature and arterial pressure were 0.735, 0.797 and 0.614, respectively.

Conclusion

Heart rate, APACHE Ⅱ score and GCS score can be adopted as the clinical prognostic indicators for the patients with thermoplegia.

表1 存活组与死亡组入院时生命体征比较
表2 存活组与死亡组住院时间及MODS发生率比较
图1 入院时心率、GCS评分及APACHE Ⅱ评分在评估热射病患者预后中的价值
表3 各指标在预测热射病患者死亡中的价值
1
Mozzini C, Xotta G, Garbin U, et al. Non-Exertional Heatstroke: A case report and review of the literature[J]. Am J Case Rep, 2017, 18: 1058-1065.
2
刘 军,邹桂娟,吴允孚,等. 中暑致多器官功能障碍综合征9例临床分析并文献复习[J]. 中华危重病急救医学,2015, 27(8): 695-699.
3
范纯泉,陈长青,唐卓夫,等. 军事训练致劳力性热射病28例临床救治体会[J]. 海南医学,2016, 27(2): 290-291.
4
Hifumi T, Kondo Y, Shimizu K, et al. Heat stroke[J]. J Intensive Care, 2018, 6: 30.
5
Argaud L, Ferry T, Le QH, et al. Short- and long-term outcomes of heatstroke following the 2003 heat wave in Lyon, France[J]. Arch Intern Med, 2007, 167(20): 2177-2183.
6
王海滔. 职业性中暑诊断标准[J]. 职业卫生与应急救援,2009, 27(4): 174.
7
周京江,赵佳佳,周飞虎,等. APACHEⅡ评分对劳力性热射病患者预后判断的价值[J]. 解放军医学院学报,2013, 25(11): 1141-1143.
8
Abdelmoety DA, El-Bakri NK, Almowalld WO, et al. Characteristics of heat illness during Hajj: A cross-sectional study[J]. Biomed Res Int, 2018, 2018: 5629474.
9
White JR, Berisha V, Lane K, et al. Evaluation of a novel syndromic surveillance query for heat-related illness using hospital data from maricopa county, Arizona, 2015[J]. Public Health Rep, 2017, 132(1_suppl): 31S-39S.
10
王洪萍,莎 宁,秦秀菊,等. 热射病的发病学特点及流行病学进展[J]. 中华危重病急救医学,2015, 27(8): 702-704.
11
丁国娟,任 疆,陈亚涛. 劳力性热射病合并多器官功能障碍综合征29例临床分析[J]. 中国医药导报,2014, 11(19): 59-61.
12
Leon LR, Helwig BG. Heat stroke: role of the systemic inflammatory response[J]. J Appl Physiol (1985), 2010, 109(6): 1980-1988.
13
李英华,刘淑红,郭素青,等. 热射病血液系统损害的临床分析[J]. 山东医药,2011, 51(44): 89-90.
14
汪正权,屠旭旦,陆 雯,等. 热射病患者临床预后的预测指标分析[J]. 中华急诊医学杂志,2016, 25(8): 1058-1061.
15
赵佳佳,周京江,胡 婕,等. 影响劳力性热射病预后的危险因素分析[J]. 中华危重病急救医学,2013, 25(9): 515-518.
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