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中华肺部疾病杂志(电子版) ›› 2023, Vol. 16 ›› Issue (06) : 877 -879. doi: 10.3877/cma.j.issn.1674-6902.2023.06.031

短篇论著

肿瘤标志物在肺癌鉴别诊断中的预测价值
洪俊(), 张春来, 鲍黄胜   
  1. 231500 庐江,安徽省庐江县人民医院肿瘤科
  • 收稿日期:2023-10-07 出版日期:2023-12-25
  • 通信作者: 洪俊

Predictive value of tumor markers in differential diagnosis of lung cancer

Jun Hong(), Chunlai Zhang, Huangsheng Bao   

  • Received:2023-10-07 Published:2023-12-25
  • Corresponding author: Jun Hong
引用本文:

洪俊, 张春来, 鲍黄胜. 肿瘤标志物在肺癌鉴别诊断中的预测价值[J]. 中华肺部疾病杂志(电子版), 2023, 16(06): 877-879.

Jun Hong, Chunlai Zhang, Huangsheng Bao. Predictive value of tumor markers in differential diagnosis of lung cancer[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2023, 16(06): 877-879.

肺癌(carcinoma of the lungs)是严重威胁人类生命健康的恶性肿瘤,发病率和病死率全球范围位居第一[1,2]。多数发现时已进入晚期,5年生存率低[3,4,5]。肺癌病理类型分为非小细胞肺癌(non-small cell lung cancer, NSCLC)及小细胞肺癌(small cell lung cancer, SCLC),快速确定病理分型是提高肺癌生存率、改善预后的关键[6,7]。血清肿瘤标志物为无创检查,对肺癌诊断、治疗及预后有临床意义[8,9,10]。癌胚抗原(carcinoembryonic antigen, CEA)、神经元特异性烯醇化酶(neuron specific enolase, NSE)、细胞角蛋白19片段(cytokeratin 19 fragment, CYFRA21-1)是原发性肺癌诊疗中常见血清肿瘤标志物,联合检测在鉴别诊断不同病理分型肺癌中报道尚少[11,12,13]。本文对我院收治的46例肺癌患者CEA、NSE、CYFRA21-1联合检测进行分析,报道如下。

表1 肺癌患者的一般资料结果比较[n(%)]
表2 CEA、NSE、CYFRA21-1水平比较(±s,ng/ml)
表3 多因素Logistic回归分析
表4 不同病理分型肺癌鉴别诊断价值
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