切换至 "中华医学电子期刊资源库"

中华肺部疾病杂志(电子版) ›› 2021, Vol. 14 ›› Issue (01) : 114 -116. doi: 10.3877/cma.j.issn.1674-6902.2021.01.028

综述

他汀类药物在慢性阻塞性肺疾病及其合并症中的应用进展
张雯1, 李传伟2, 杨丽1, 李琦1,(), 王关嵩1,()   
  1. 1. 400037 重庆,陆军(第三)军医大学第二附属医院全军呼吸内科研究所、呼吸与危重症医学科
    2. 400042 重庆,陆军(第三)特色医学中心心血管内科
  • 收稿日期:2020-10-08 出版日期:2021-02-25
  • 通信作者: 李琦, 王关嵩
  • 基金资助:
    国家科技部重点研发计划(2016YFC1304503)

Progress of statins in chronic obstructive pulmonary disease and its complications

Wen Zhang1, Chuanwei Li2, Li Yang1   

  • Received:2020-10-08 Published:2021-02-25
引用本文:

张雯, 李传伟, 杨丽, 李琦, 王关嵩. 他汀类药物在慢性阻塞性肺疾病及其合并症中的应用进展[J]. 中华肺部疾病杂志(电子版), 2021, 14(01): 114-116.

Wen Zhang, Chuanwei Li, Li Yang. Progress of statins in chronic obstructive pulmonary disease and its complications[J]. Chinese Journal of Lung Diseases(Electronic Edition), 2021, 14(01): 114-116.

1
任成山,王关嵩,钱桂生. 慢性阻塞性肺疾病的成因及其治疗的困惑与希望[J/CD]. 中华肺部疾病杂志(电子版), 2019, 12(2): 127-141.
2
Lahousse L, Loth DW, Joos GF, et al. Statins, systemic inflammation and risk of death in COPD: the Rotterdam study[J]. Pulm Pharmacol Ther, 2013, 26(2): 212-217.
3
Ingebrigtsen TS, Marott JL, Nordestgaard BG, et al. Statin use and exacerbations in individuals with chronic obstructive pulmonary disease[J]. Thorax, 2015, 70(1): 33-40.
4
Fatehi Hassanabad A. Current perspectives on statins as potential anti-cancer therapeutics: clinical outcomes and underlying molecular mechanisms[J]. Transl Lung Cancer Res, 2019, 8(5):692-699.
5
Young RP, Hopkins RJ. The mevalonate pathway and innate immune hyperresponsiveness in the pathogenesis of COPD and Lung cancer: potential for chemoprevention[J]. Curr Mol Pharmacol, 2017, 10: 46-59.
6
Lam DC, Luo SY, Fu KH, et al. Nicotinic acetylcholine receptor expression in human airway correlates with lung function[J]. Am J Physiol Lung Cell Mol Physiol, 2016, 310: L232-L239.
7
Hopkins RJ, Young RP. Mevalonate signaling, COPD and cancer: the statins and beyond[J]. J Investig Med, 2019, 67(4): 711-714.
8
Walsh A, Perrem L, Khashan AS, et al. Statins versus placebo for people with chronic obstructive pulmonary disease[J]. Cochrane Database Syst Rev, 2019, 7: CD011959.
9
Lu Y, Chang R, Yao J, et al. Effectiveness of long-term using statins in COPD-a network meta-analysis[J]. Respir Res, 2019, 20(1): 17.
10
Vogelmeier CF, Criner GJ, Martinez FJ, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report. Gold executive summary[J]. Am J Respir Crit Care Med, 2017, 195: 557-582.
11
Zhang W, Zhang Y, Li CW, et al. Effect of statins on chronic obstructive pulmonary disease: a meta-analysis of randomized controlled trials[J]. Chest, 2017, 152(6): 1159-1168.
12
Thomson NC. Clinical Studies of Statins in Asthma and COPD[J]. Curr Mol Pharmacol, 2017, 10(1): 60-71.
13
Su VY, Yang YH, Perng DW, et al. Real-world effectiveness of medications on survival in patients with COPD-heart failure overlap[J]. Aging (Albany NY), 2019, 11(11): 3650-3667.
14
Chaouat A, Bugnet AS, Kadaoui N, et al. Severe pulmonary hypertension and chronic obstructive pulmonary disease[J]. Am J Respi Crit Care Med, 2005, 172: 189-194.
15
Oswald-Mammosser M, Weitzenblum E, Quoix E, et al. Prognostic factors in COPD patients receiving long-term oxygen therapy. Importance of pulmonary artery pressure[J]. Chest, 1995, 107: 1193-1198.
16
Katsiki N, Wierzbicki AS, Mikhailidis DP. Pulmonary arterial hypertension and statins: an update[J]. Curr Opin Cardiol, 2011, 26: 322,326.
17
Wang G, Shang W, Ren Y, et al. Benefits of statins in chronic obstructive pulmonary disease patients with pulmonary hypertension: A meta-analysis[J]. Eur J Intern Med, 2019, 70: 39-42.
18
Houghton AM. Mechanistic links between COPD and lung cancer[J]. Nat Rev Cancer, 2013, 13(4): 233-245.
19
Young RP, Hopkins RJ. The mevalonate pathway and innate immune hyper responsiveness in the pathogenesis of COPD and Lung cancer: potential for chemoprevention[J]. Curr Mol Pharmacol, 2017, 10: 46-59.
20
Ridker PM, MacFadyen JG, Thuren T, et al. Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial[J]. Lancet , 2017, 390: 1833-1842.
21
Ahern TP, Pedersen L, Tarp M, et al. Statin prescriptions and breast cancer recurrence risk: a Danish nationwide prospective cohort study[J]. J Natl Cancer Inst, 2011, 103: 1461-1468.
22
Nielsen SF, Nordestgaard BG, Bojesen SE. Statin use and reduced cancer related mortality[J]. N Engl J Med, 2012, 367: 1792-1802.
23
Chen YF, Li XL, Zhang R, et al. Effects of statin exposure and lung cancer survival: A meta-analysis of observational studies[J]. Pharmacol Res, 2019, 141: 357-365.
24
Xia DK, Hu ZG, Tian YF, et al. Statin use and prognosis of lung cancer: a systematic review and meta-analysis of observational studies and randomized controlled trials[J]. Drug Des Devel Ther, 2019, 13: 405-422.
[1] 马锦芳, 何正光, 郑劲平. 盐酸氨溴索雾化吸入治疗慢性阻塞性肺疾病黏痰症患者的疗效和安全性分析[J]. 中华肺部疾病杂志(电子版), 2024, 17(04): 568-574.
[2] 程炜炜, 张青, 张诚实, 冯契靓, 陈荣荣, 赵云峰. 全身免疫炎症指数与慢性阻塞性肺疾病急性加重期病情严重程度相关性分析[J]. 中华肺部疾病杂志(电子版), 2024, 17(04): 580-584.
[3] 杨万荣, 任治坤, 时新颍. 沙丁胺醇雾化吸入脾多肽治疗AECOPD的疗效分析[J]. 中华肺部疾病杂志(电子版), 2024, 17(04): 609-612.
[4] 赖乾德, 吕相琴, 蔺洋, 刘媛梅, 赵春艳, 李琦. 肝素结合蛋白对慢性阻塞性肺疾病预后预测分析[J]. 中华肺部疾病杂志(电子版), 2024, 17(04): 613-616.
[5] 王微, 丁霖, 陈茜, 呼延欣, 闫蓓. 综合治疗对慢性阻塞性肺疾病的疗效及转归影响分析[J]. 中华肺部疾病杂志(电子版), 2024, 17(04): 621-624.
[6] 方晓玉, 王婷, 赵珊, 陈锋. HALP指数对AECOPD并发呼吸衰竭患者ICU结局的预测意义[J]. 中华肺部疾病杂志(电子版), 2024, 17(04): 639-641.
[7] 郭少琳, 郭建英, 左秀萍, 高苗. 慢性阻塞性肺疾病康复训练依从性影响因素分析[J]. 中华肺部疾病杂志(电子版), 2024, 17(04): 652-654.
[8] 白若靖, 郭军. 维生素D对肺部疾病临床意义的研究进展[J]. 中华肺部疾病杂志(电子版), 2024, 17(04): 659-662.
[9] 孔令梅, 徐晓媛, 马丽颖. 慢性阻塞性肺疾病认知衰弱危险因素及预后分析[J]. 中华肺部疾病杂志(电子版), 2024, 17(03): 407-410.
[10] 袁广琴, 朱珠, 林云霞. 胸腺肽联合无创正压通气救治AECOPD并发Ⅱ型呼吸衰竭患者的临床分析[J]. 中华肺部疾病杂志(电子版), 2024, 17(03): 438-441.
[11] 徐艳, 江秀娟, 王超, 江圆满. 股直肌剪切波弹性成像对COPD并发肌少症的诊断意义[J]. 中华肺部疾病杂志(电子版), 2024, 17(03): 454-457.
[12] 黄映兰, 骆丽萍, 郭慧玲, 袁麟标. 慢性阻塞性肺疾病糖皮质激素治疗反应性的影响因素分析[J]. 中华肺部疾病杂志(电子版), 2024, 17(03): 469-471.
[13] 杨坤, 赵景成, 吴永强. 无创呼吸机在慢性阻塞性肺疾病并发呼吸衰竭救治的临床分析[J]. 中华肺部疾病杂志(电子版), 2024, 17(03): 481-483.
[14] 闫维, 张二明, 张克, 安欣华, 向平超. 北京市石景山区40岁及以上居民早期慢性阻塞性肺疾病异质性及影响因素分析[J]. 中华临床医师杂志(电子版), 2024, 18(06): 533-540.
[15] 何秀, 敖的, 杨郑, 林小华. 改良呼吸支持策略对慢性阻塞性肺疾病急性加重合并Ⅱ型呼吸衰竭患者的疗效[J]. 中华卫生应急电子杂志, 2024, 10(03): 140-144.
阅读次数
全文


摘要